Apstatin analogue inhibitors of aminopeptidase P, a bradykinin-degrading enzyme

Journal of Medicinal Chemistry

Volumn 42, Issue 13, 1999, Pages 2394-2402

  Maggiora, Linda L ^a   Orawski, Arthur T ^b   Simmons, William H ^b  

^a PFIZER INC   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(3 AMINO 2 HYDROXY 5 METHYLHEXANOYL)PROLYLPROLYLALANILAMIDE; AMINOPEPTIDASE P; AMINOPEPTIDASE P INHIBITOR; APSTATIN; BRADYKININ; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CATTLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITOR INTERACTION; ESCHERICHIA COLI; HUMAN; HUMAN CELL; INHIBITION KINETICS; MONKEY; NONHUMAN; RAT; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; VASODILATATION;

AMINOPEPTIDASES; ANIMALS; BLOOD PLATELETS; BRADYKININ; CATTLE; CELL MEMBRANE; DIPEPTIDASES; ESCHERICHIA COLI; HUMANS; HYDROXAMIC ACIDS; ISOENZYMES; KIDNEY; LEUCYL AMINOPEPTIDASE; LUNG; MACACA FASCICULARIS; MYOCARDIUM; OLIGOPEPTIDES; PEPTIDES; PROTEASE INHIBITORS; RATS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SULFHYDRYL COMPOUNDS; SWINE;

EID: 0033168840     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9805642     Document Type: Article

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