Non-separating effects in a centrifugal partition chromatographic reactor for the enzymatic production of L-amino acids

Chemical Engineering Science

Volumn 54, Issue 15-16, 1999, Pages 3207-3215

  Den Hollander, Jeroen L ^a   Yiu, Wai Wong ^a   Luyben, Karel Ch A M ^a   Van der Wielen, Luuk A M ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

Aqueous two phase systems; Centrifugal partition chromatography; Chromatographic reaction

Indexed keywords

AMINO ACIDS; ENZYME KINETICS; ENZYMES; HYDROLYSIS; MASS TRANSFER; MATHEMATICAL MODELS; PHASE COMPOSITION; REACTION KINETICS; STABILITY; SUBSTRATES;

AQUEOUS TWO PHASE SYSTEMS; CENTRIFUGAL PARTITION CHROMATOGRAPHY; CHIRAL AMINO ACIDS; CHROMATOGRAPHIC REACTOR; DAMKOHLERS NUMBER; DILUTION; SELECTIVE ENZYMATIC HYDROLYSIS;

LIQUID CHROMATOGRAPHY;

CHROMATOGRAPHY; LIQUID-LIQUID SEPARATION;

EID: 0033167017     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2509(98)00347-9     Document Type: Article

References (12)

1. Albertsson, P.Å. (1986). Partition of Cells, Particles and Macromolecules (3rd Ed.). New York: Wiley-Interscience.
2. Buel, M.J. van, Wielen L.A.M. van der, & Luyben, K.Ch.A.M. (1997). Effluent concentration profiles in centrifugal partition chromatography. A.I.Ch.E. J., 43 (3), 693-702.
3. Coca, J., Adrio, G., Jeng, C.-Y., Langer, S.H. (1993). In: G. Ganetsos, & P.E. Barker (Eds.), Preparative and Production Scale Chromatography (pp. 449-475). New York: Marcel Dekker.
4. Cohen, L.M., Eiteman, M.A., & Gainer, J.L. (1995). A model to predict the partition coefficient of amino acids in PEG/Salt aqueous two-phase systems. Sep. Sci. Technol., 30 (2), 225-237.
5. Foucault, A.P. (Ed.) (1995). Centrifugal Partition Chromatography. New York: Marcel Dekker.
6. Haynes, C.A., Benitez, F.J., Blanch, H.W., & Prausnitz, J.M. (1993). Application of integral-equation theory to aqueous two-phase partitioning systems. A.I.Ch.E. J., 39, 1539-1557.
7. Hollander, J.L. den, Stribos, B.I., Buel M.J. van, Luyben, K.Ch.A.M., & Wielen, L.A.M. van der (1998). J. Chromatogr. B., 711, 223-235.
8. Ito, Y. (1996). In: Y. Ito, & W.D. Conway (Eds.), High Speed Countercurrent Chromatography (pp. 3-44). New York: Wiley.
9. Jansen, M., Zessen, E. van, Straathof, A.J.J., Wielen, L.A.M. van der, Luyben, K.Ch.A.M., & Tweel, W.J.J. van (1996). Ann. N.Y. Acad. Sci., Enzyme Engng XIII.
10. Mazzotti, M., Neri, B., Gelosa, D., & Morbidelli, M. (1997). Ind. Engng Chem. Res., 36, 3163-3172.
11. Sardin, M., Schweich, D., & Villermaux, J. (1993). In: G. Ganetsos, & P.E. Barker (Eds.), Preparative and Production Scale Chromatography (pp. 477-521). New York: Marcel Dekker.
12. Wandrey, W., & Flaschel, E. (1979). In: T.K. Ghose, A. Fiechter, A., & N. Blakebrough (Eds.), Advances in Biochemical Engineering (Vol. 2, pp. 148-218). Heidelberg: Berlin.