Antisense inhibition of the GDP-mannose pyrophosphorylase reduces the ascorbate content in transgenic plants leading to developmental changes during senescence

Plant Journal

Volumn 19, Issue 2, 1999, Pages 131-141

  Keller, Ruth ^a   Springer, Franziska ^a   Renz, Andreas ^a   Kossmann, Jens ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR PLANT PHYSIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; BIOCHEMICAL PATHWAY; BIOSYNTHESIS; CELL WALL; COMPLEMENTARY DNA; DNA ISOLATION; ENZYME INHIBITION; GLYCOSYLATION; MANNOSE 1 PHOSPHATE GUANYLYLTRANSFERASE; PHENOTYPE; PROMOTER REGION; SENESCENCE; TISSUE CULTURE; TRANSGENIC PLANT; WILD RELATIVE;

AMINO ACID SEQUENCE; ASCORBIC ACID; CARBOHYDRATE METABOLISM; CARRIER PROTEINS; CELL WALL; CELLULOSE; CLONING, MOLECULAR; COLLECTINS; DNA, ANTISENSE; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, PLANT; GLUCOSE; GLYCOSYLATION; LECTINS; MANNOSE; MOLECULAR SEQUENCE DATA; NUCLEOTIDYLTRANSFERASES; PHENOTYPE; PLANT LEAVES; PLANT LECTINS; PLANT PROTEINS; PLANTS, GENETICALLY MODIFIED; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SOLANUM TUBEROSUM; SOLUBILITY; STARCH; TISSUE DISTRIBUTION;

EMBRYOPHYTA; SOLANUM TUBEROSUM; TUBEROSUM;

EID: 0033166997     PISSN: 09607412     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-313X.1999.00507.x     Document Type: Article

References (42)

1. Altschul, S.F., Gish, W., Miller, W., Meyers, E.W. and Lipman, D.J. (1990) Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
2. Amasino, R.M. (1986) Acceleration of nucleic acid hybridization rate by polyethylene glycol. Anal. Biochem. 152, 304-307.
3. Barber, G.A. (1968) The synthesis of guanosine 5′-diphosphate D-rhamnose by enzymes of higher plants. Biochim. Biophys. Acta, 165, 68-75.
4. Barber, G.A. (1969) The synthesis of guanosin 5′-diphosphate D-rhamnose. Biochemistry, 8, 3692-3695.
5. 3H] Mannose incorporation in cultured plant cells: Investigation of L-galactose residues of the primary cell wall. J. Plant Physiol. 132, 484-490.
6. Benton, B.K., Plump, S.D., Roos, J., Lennarz, W.J. and Cross, F.R. (1996) Over-expression of S. cerevisiae G1 cyclins restores the viability of alg1 N-glycosylation mutants. Curr. Genet. 29, 106-113.
7. Bonin, C.P., Potter, I., Vanzin, G.F. and Reiter, W.D. (1997) The MUR1 gene of Arabidopsis thaliana encodes an isoform of GDP-D-mannose-4,6-dehydratase catalysing the first step in the de novo synthesis of GDP-L-fucose. Proc. Natl Acad. Sci. USA, 93, 12637-12642.
8. Bradford, M.M. (1976) Rapid and quantitative method for quantitation of microgramm quantities of protein utilizing the principle protein-dye binding. Anal. Biochem. 72, 248-252.
9. Brett, C.T. and Waldron, K.W. (1996). The molecular components of the wall. In Physiology and Biochemistry of Plant Cell Walls 2nd edition. London: Chapman & Hall, pp. 4-43.
10. Carpita, N.C. and Gibeaut, D.M. (1993) Structural models of the primary cell walls in flowering plants: consistency of molecular structure with the physical properties of the walls during growth. Plant J. 3, 1-30.
11. Conklin, P.L. (1998) Vitamin C: a new pathway for an old antioxidant. Trends Plant Sci. 3, 329-330.
12. Conklin, P.L., Norris, S.R., Wheeler, G.L., Williams, E.H., Smirnoff, N. and Last, R.L. (1999) Genetic evidence for the role of GDP-mannose in plant ascorbic acid (vitamin C) biosynthesis. Proc. Natl Acad. Sci. USA, 96, 4198-4203.
13. Conklin, P.L., Pallanca, J.E., Last, R.L. and Smirnoff, N. (1997) L-Ascorbic acid metabolism in the ascorbate-deficient Arabidopsis-mutant vtc1. Plant Physiol. 115, 1277-1285.
14. Conklin, P.L, Williams, E.H. and Last, R.L. (1996) Environmental stress sensitivity of an ascorbic acid-deficient Arabidopsis mutant. Proc. Natl Acad. Sci. USA, 93, 9970-9974.
15. Deblaere, R., Bytebier, B., de Greve, H., Debroek, F., Schell, J., van Montagu, M. and Leemans, J. (1985) Efficient octopine Ti plasmid-derived vectors of Agrobacterium mediated gene transfer to plants. Nucl. Acids Res. 13, 4777-4788.
16. Debray, H. and Montreul, J. (1989) Aleuria aurantia agglutinin. A new isolation procedure and further study of its specificity towards various glycopeptides and oligosaccharides. Carbohydr. Res. 185, 15-26.
17. Devereux, J., Haeberli, P. and Smithies, O. (1984) A comprehensive set of sequence analysis programs for the VAX. Nucl. Acids Res. 12, 387-395.
18. Dormann, P. and Benning, C. (1996) Functional expression of uridine 5′-diphospho-glucose-4-epimerase (EC 5.1.3.2) from Arabidopsis thaliana in Saccharomyces cerevisiae and Escherichia coli. Arch. Biochem. Biophys. 327, 27-34.
19. Feingold, D.S. and Avigad, G. (1980) Sugar nucleotide transformations in plants. In The Biochemistry of Plants (Preiss, J., ed.) New York: Academic Press, pp. 102-170.
20. Garg, O.P. and Kapoor, V. (1972) Retardation of leaf senescence by ascorbate. J. Exp. Bot. 23, 699-704.
21. nd edn. Oxford: Oxford University Press.
22. Höfgen, R. and Willmitzer, L. (1990) Biochemical and genetic analysis of different patatin isoforms expressed in various organs of potato (Solanum tuberosum L.). Plant Sci. 66, 221-230.
23. Kampfenkel, K., van Montagu, M. and Inzé, D. (1995) Extraction and determination of ascorbate and dehydroascorbate from plant tissue. Anal. Biochem. 225, 165-167.
24. Koßmann, J., Mueller-Roeber, B., Dyer, T.A., Raines, C.A., Sonnewald, U. and Willmitzer, L. (1992) Cloning and expression analysis of the plastidic fructose-1,6-bisphosphatase coding sequence from potato. Circumstantial evidence for the import of hexoses into chloroplasts. Planta, 188, 7-12.
25. Laemmli, U.K. (1970) Clevage of structural proteins during assembly of the head of bacteriophage T4. Nature, 277, 680-685.
26. Logemann, J., Schell, J. and Willmitzer, L. (1987) Improved method for the isolation of RNA from plant tissues. Anal. Biochem. 163, 16-20.
27. Marolda, C.L. and Valvano, M.A. (1993) Identification, expression and DNA sequence of the GDP-mannose biosynthesis genes encoded by the 07 rfb gene cluster of strain VW187 (Escherichia coli 07. K1). J. Bacteriol. 175, 148-158.
28. Müller-Röber, B., Sonnewald, S. and Willmitzer, L. (1992) Inhibition of the ADP-glucose pyrophosphorylase in transgenic potatoes leads to sugar-storing tubers and influences tuber formation and expression of tuber storage protein genes. EMBO J. 11, 1229-1238.
29. Pearson, W.R. and Lipman, D.J. (1988) Improved tools for biological sequence comparison. Proc. Natl Acad. Sci. USA, 85, 2444-2448.
30. Reiter, W.-D. (1998) The molecular analysis of cell wall components. Trends Plant Sci. 3, 27-32.
31. Reiter, W.-D., Chappie, C.C.S. and Sommerville, C.R. (1993) Altered growth and cell walls in a fucose-deficient mutant of Arabidopsis. Science, 261, 1032-1035.
32. del Rio, L.A., Pastori, G.M., Palma, J.M., Sandalio, L.M., Sevilla, F., Corpas, F.J., Jiménez, A., López-Huertas, E. and Hernández, J.A. (1998) The actvated oxygan role of peroxisomes in senescence. Plant Physiol. 116, 1195-1200.
33. Rocha-Sosa, M., Sonnewald, U., Frommer, W., Stratmann, M., Schell, J. and Willmitzer, L. (1989) Both developmental and metabolic signals activate the promoter of class I patatin gene. EMBO J. 8, 23-29.
34. nd edn Cold Spring Harbour: Cold Spring Harbour Laboratory Press.
35. Sanger, F., Nicklen, S. and Coulson, A.R. (1977) DNA sequencing with chain-termination inhibitors. Proc. Natl Acad. Sci. USA, 74, 5463-5467.
36. von Schéele, C., Swensson, G. and Rassmuson, J. (1937) Die Bestimmung des Stärkegehalts und der Trockensubstanz der Kartoffel mit Hlfe des spezifischen Gewichts. Landw. Vers. Sta. 127, 67-96.
37. Shibuya, N., Goldstein, I.J., Van Damme, E.J.M. and Peumans, W.J. (1988) Binding properties of a mannose-specific lectin from the snowdrop (Galanthus nivalis) bulb. J. Biol. Chem. 263, 728-734.
38. Shinabarger, D., Berry, A., May, T.B., Rothmel, R., Fialho, A. and Chakrabarty, A.M. (1991) Purification and characterization of phosphomannose isomerase-guanosine diphospho-D-mannose pyrophosphorylase. J. Biol. Chem. 266, 2080-2088.
39. Szumilo, T., Drake, R.R., York, J.L. and Elbein, A.D. (1993) GDP-mannose pyrophosphorylase. Purification to homogenity, properties, and utilization to prepare photoaffinity analogs. J. Biol. Chem. 268, 17943-17950.
40. Tenhaken, R. and Thulke, O. (1996) Cloning of an enzyme that synthesizes a key nucleotide-sugar precursor of hemicellulose biosynthesis from soybean: UDP-glucose dehydrogenase. Plant Physiol. 112, 1127-1134.
41. Vervliet, P., Holster, M., Teuchy, H., van Montagu, M. and Schell, J. (1975) Characterisation of different plaque-forming and defective temperante phages in Agrobacterium strains. J. Gen. Virol. 26, 33-48.
42. Wheeler, G.L., Jones, M.A. and Smirnoff, N. (1998) The biosynthetic pathway of vitamin C in higher plants. Nature, 393, 365-369.