Atypical Mucocutaneous Leishmaniasis Caused by Leishmania braziliensis in an Acquired Immunodeficiency Syndrome Patient: T-cell Responses and Remission of Lesions Associated with Antigen Immunotherapy

Memorias do Instituto Oswaldo Cruz

Volumn 94, Issue 4, 1999, Pages 537-542

  Da Cruz, Alda M ^a   Filgueiras, Danilo V ^b   Coutinho, Ziadir ^b   Mayrink, Wilson ^c   Grimaldi Jr , Gabriel ^a   De Luca, Paula M ^a   Mendonça, Sergio C F ^a   Coutinho, Sergio G ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b HOSPITAL UNIVERSITÁRIO GAFFRÉE E GUINLE   (Brazil)

^c FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

Acquired immunodeficiency syndrome; CD8+ cells; Human mucocutaneous leishmaniasis; Immunotherapy; Interferon

Indexed keywords

LEISHMANIA BRAZILIENSIS;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL; ARTICLE; CELLULAR IMMUNITY; IMMUNOLOGY; IMMUNOTHERAPY; LEISHMANIA BRAZILIENSIS; SKIN LEISHMANIASIS; T LYMPHOCYTE;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANIMALS; IMMUNITY, CELLULAR; IMMUNOTHERAPY; LEISHMANIA BRAZILIENSIS; LEISHMANIASIS, MUCOCUTANEOUS; T-LYMPHOCYTES;

EID: 0033160478     PISSN: 00740276     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0074-02761999000400020     Document Type: Article

References (29)

1. Alvar J, Cañavate C, Gutiérrez-Solar B, Jiménez M, Laguna F, López-Vélez R, Molina R, Moreno J 1997. Leishmania and human immunodeficiency virus confection: the first 10 years. Clin Microbiol Rev 10: 298-319.
2. Badaró R 1997. When Leishmania and HIV interact, a new broad spectrum of leishmaniasis occurs. Braz J Infect Dis 1: 145-148.
3. CDC 1993. Revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults 1992. MMWR 41: 1-19.
4. Cimerman S, Gomes MCO 1993. AIDS associada a leishmaniose cutaneomucosa. J Bras Med 65: 212-213.
5. + cytotoxic T cell responses. Eur J Immunol 24: 2813-2817.
6. Carvalho EM, Johnson WD, Barreto E, Marsden PD, Costa JLM, Reed S, Rocha H 1985. Cell mediated immunity in American cutaneous and mucosal leishmaniasis. J Immunol 135: 4144-4148.
7. Convit J, Castellanos PL, Rondon JA, Pinardi ME, Ulich M, Castes M, Bloom B, Garcia L 1987. Immunotherapy versus chemotherapy in localized cutaneous leishmaniasis. Lancet i: 401-404.
8. Convit J, Pinardi ME, Rondon AJ 1972. Diffuse cutaneous leishmaniasis: a disease due to an immunological defect of the host. Trans R Soc Trop Med Hyg 66: 603-610.
9. Coura JR, Galvão-Castro B, Grimaldi Jr G 1987. Disseminated American cutaneous leishmaniasis in a patient with AIDS. Mem Inst Oswaldo Cruz 82: 581-582.
10. Coutinho SG, Oliveira MP, Da-Cruz AM, De Luca PM, Mendonça SCF, Bertho AL, Soong L, McMahon-Pratt D 1996. T-cell responsiveness of American cutaneous leishmaniasis patients to purified Leishmania pifanoi amastigote antigens and Leishmania braziliensis promastigote antigens: immunologic patterns associated with cure. Exp Parasitol 84: 144-155.
11. + T cells associated with cure of human cutaneous leishmaniasis. Infect Immun 62: 2614-2618.
12. Da-Cruz AM, Machado ES, Menezes JA, Menezes JA, Rutowitsch MS, Coutinho SG 1992. Cellular and humoral immune responses of a patient with American cutaneous leishmaniasis and AIDS. Trans R Soc Trop Med Hyg 86: 511-512.
13. Daudén E, Peñas PF, Rios L, Jimenez M, Fraga J, Alvar J, García-Diez A 1996. Leishmaniasis presenting as a dermatomyositis-like eruption in AIDS. J Am Acad Dermatol 35: 316-319.
14. Dedet JP, Lambert M, Pratlong F 1995. Leishmanioses et infection par le virus de l'immunodéficience humaine. Presse Med 24: 1036-1040.
15. Echevarría J, Campos P, Chang J, Cuéllar L, Gotuzzo E, Paz L, Llanos-Cuentas A 1993. Mucocutaneous leishmaniasis and AIDS: case report. Trans R Soc Trop Med Hyg 87: 186.
16. Genaro O, Toledo VPCP, Costa CA, Hermeto MV, Afonso LCC, Mayrink W 1996. Vaccine for prophylaxis and immunotherapy, Brazil. Clin Dermatol 14: 503-512.
17. Gonzalés-Rupérez J, Morlius MJ, Carazo AM 1997. Remission of localized cutaneous leishmaniasis in a HIV-positive patient using systemic terbinafine. Dermatol 194: 85-86.
18. Gorgolas M, Castrillo JM, Fernandez Guerrero ML 1993. Visceral leishmaniasis in patients with AIDS: report of three cases treated with pentavalent antimony and interferon-gamma. Clin Infect Dis 17: 56-58.
19. Grimaldi Jr G, Momen H, Naiff RD, McMahon-Pratt D, Barrett TV 1991. Characterization and classification of leishmanial parasites from humans, wild mammals and sand flies in the Amazon region of Brazil. Am J Trop Med Hyg 44: 645-661.
20. Hernandez D, Rodriguez N, Martinez C, Garcia L, Convit J 1993. Leishmania braziliensis causing visceral leishmaniasis in a patient with human immunodeficiency virus infection, identified with the aid of the polymerase chain reaction. Trans R Soc Trop Med Hyg 87: 627-628.
21. Kovacsovics-Bankowski M, Rock KL 1995. A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science 267: 243-246.
22. Machado ES, Braga MP, Da-Cruz AM, Coutinho SG, Vieira ARM, Rutowitsch MS, Cuzzi-Maya T, Grimaldi G, Menezes JA 1992. Disseminated American muco-cutaneous leishmaniasis caused by Leishmania braziliensis braziliensis in a patient with AIDS: a case report. Mem Inst Oswaldo Cruz 87: 487-492.
23. Mayrink W, Magalhães PA, Michalick MSM, Costa CA, Lima AO, Melo MN, Toledo VP, Nascimento E, Dias M, Genaro O 1992. Immunotherapy as a treatment of American cutaneous leishmaniasis: preliminary studies in Brazil. Parassitologia 34: 159-165.
24. Mendonça SCF, De Luca PM, Mayrink W, Restom TG, Conceição-Silva F, Da-Cruz AM, Bertho AL, Costa CA, Genaro O, Toledo VPCP, Coutinho SG 1995. Characterization of human T lymphocyte-mediated immune responses induced by a vaccine against American tegumentary leishmaniasis. Am J Trop Med Hyg 53: 195-201.
25. + T cells. Infect Immun 61: 3730-3738.
26. Ortigão-de-Sampaio MB, Shattock RJ, Hayes P, Griffin GE, Linhares-de-Carvalho MI, Leon AP, Lewis DJM, Castello-Branco LRR 1998. Increase in plasma viral load after oral cholera immunization of HIV-infected subjects. AIDS 12: 145-150.
27. Rubio FA, Robayna G, Herranz P, Torres E, Pena JM, Contreras F, De Lucas R, Casado M 1997. Leishmaniasis presenting as a psoriasiform eruption in AIDS. Br J Dermatol 136: 792-806.
28. Sasaki MGM, Carvalho MM, Ferreira MLS, Machado MP 1997. Cutaneous leishmaniasis coinfection in AIDS patients: case report and literature review. Braz J Infect Dis 1: 142-144.
29. Scott P, Farrell JP 1998. Experimental cutaneous leishmaniasis: induction and regulation of T cells following infection of mice with Leishmania major. Chem Immunol 70: 60-80.