-
1
-
-
0030011909
-
Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: What we do and do not know about cytokine regulation
-
Bone RC: Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: what we do and do not know about cytokine regulation. Crit Care Med 24:163-172, 1996.
-
(1996)
Crit Care Med
, vol.24
, pp. 163-172
-
-
Bone, R.C.1
-
3
-
-
0028957549
-
Efficacy and safety of monoclonal antibody to human tumor necrosis factor a in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter clinical trial
-
TNF-alpha MAb Sepsis Study Group
-
Abraham E, Wunderink R, Silverman H, Perl TM, Nasraway S, Levy H, Bone R, Wenzel RP, Balk R, Allred R, et al.: Efficacy and safety of monoclonal antibody to human tumor necrosis factor a in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter clinical trial. TNF-alpha MAb Sepsis Study Group. JAMA 273:934-941, 1995.
-
(1995)
JAMA
, vol.273
, pp. 934-941
-
-
Abraham, E.1
Wunderink, R.2
Silverman, H.3
Perl, T.M.4
Nasraway, S.5
Levy, H.6
Bone, R.7
Wenzel, R.P.8
Balk, R.9
Allred, R.10
-
4
-
-
0029900294
-
Treatment of septic shock with the tumor necrosis factor/Fc fusion protein
-
Fischer CJ, Agosti JM, Opal SM, Lowry SF, Balk RA, Sadoff JC, Abraham E, Schein RM, Benjamin E: Treatment of septic shock with the tumor necrosis factor/Fc fusion protein. N Engl J Med 334:1697-1702, 1996.
-
(1996)
N Engl J Med
, vol.334
, pp. 1697-1702
-
-
Fischer, C.J.1
Agosti, J.M.2
Opal, S.M.3
Lowry, S.F.4
Balk, R.A.5
Sadoff, J.C.6
Abraham, E.7
Schein, R.M.8
Benjamin, E.9
-
5
-
-
0027297663
-
Mice deficient for the 55kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
-
Pfeffer K, Matsuyama T, Kundig TM, Wakeham A, Kishihara K, Shahinian A, Wiegemann K, Ohashi PS, Kronke M, Mak TW: Mice deficient for the 55kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 73:457-467, 1993.
-
(1993)
Cell
, vol.73
, pp. 457-467
-
-
Pfeffer, K.1
Matsuyama, T.2
Kundig, T.M.3
Wakeham, A.4
Kishihara, K.5
Shahinian, A.6
Wiegemann, K.7
Ohashi, P.S.8
Kronke, M.9
Mak, T.W.10
-
6
-
-
0028979703
-
Tumor necrosis factor-α is required in the protective immune response against Mycobacterium tuberculosis in mice
-
Flynn JL, Goldstein MM, Chan J, Triebold KJ, Pfeffer K, Lowenstein CJ, Schreiber R, Mak TW, Blom BR: Tumor necrosis factor-α is required in the protective immune response against Mycobacterium tuberculosis in mice. Immunity 2:561-572, 1995.
-
(1995)
Immunity
, vol.2
, pp. 561-572
-
-
Flynn, J.L.1
Goldstein, M.M.2
Chan, J.3
Triebold, K.J.4
Pfeffer, K.5
Lowenstein, C.J.6
Schreiber, R.7
Mak, T.W.8
Blom, B.R.9
-
7
-
-
0020459622
-
Regulation of macrophage-mediated tumor cell killing by prostaglandins: Comparison of the effects of PGE2 and PGI2
-
Taffet SM, Eurell TE, Russel SW: Regulation of macrophage-mediated tumor cell killing by prostaglandins: comparison of the effects of PGE2 and PGI2. Prostaglandins 24:763-774, 1982.
-
(1982)
Prostaglandins
, vol.24
, pp. 763-774
-
-
Taffet, S.M.1
Eurell, T.E.2
Russel, S.W.3
-
8
-
-
0025889028
-
IL-10 inhibits cytokine production by activated macrophages
-
Fiorentino DF, Zlotnik A, Mosman TR, Howard M, O'Garra A: IL-10 inhibits cytokine production by activated macrophages. J Immunol 147: 3815-3822, 1991.
-
(1991)
J Immunol
, vol.147
, pp. 3815-3822
-
-
Fiorentino, D.F.1
Zlotnik, A.2
Mosman, T.R.3
Howard, M.4
O'Garra, A.5
-
9
-
-
0028826247
-
Clinical and biological significance of interleukin-10 plasma levels in patients with septic shock
-
Marchant A, Alegre ML, Hakim A, Pierard G, Marecaux G, Friedman G, de Groote D, Kahn RJ, Vincent JL, Goldman M: Clinical and biological significance of interleukin-10 plasma levels in patients with septic shock. J Clin Immunol 15:266-273, 1995.
-
(1995)
J Clin Immunol
, vol.15
, pp. 266-273
-
-
Marchant, A.1
Alegre, M.L.2
Hakim, A.3
Pierard, G.4
Marecaux, G.5
Friedman, G.6
De Groote, D.7
Kahn, R.J.8
Vincent, J.L.9
Goldman, M.10
-
10
-
-
0026087202
-
Alterations in function and phenotype of monocytes from patients with septic disease: Predictive value and new therapeutic strategies
-
Volk HD, Thieme M, Heym S, Docke WD, Ruppe U, Tausch W, Manger D, Zuckermann S, Golosubow A, Nieter B, et al.: Alterations in function and phenotype of monocytes from patients with septic disease: predictive value and new therapeutic strategies. Behring Inst Mitt 208-215, 1991.
-
(1991)
Behring Inst Mitt
, pp. 208-215
-
-
Volk, H.D.1
Thieme, M.2
Heym, S.3
Docke, W.D.4
Ruppe, U.5
Tausch, W.6
Manger, D.7
Zuckermann, S.8
Golosubow, A.9
Nieter, B.10
-
11
-
-
0029848463
-
Endotoxin tolerance after severe injury and its regulatory mechanisms
-
Keel M, Schregenberger N, Streckholzer U, Ungethum U, Kenney J, Trentz O, Ertel W: Endotoxin tolerance after severe injury and its regulatory mechanisms. J Trauma 41(3):430-443, 1996.
-
(1996)
J Trauma
, vol.41
, Issue.3
, pp. 430-443
-
-
Keel, M.1
Schregenberger, N.2
Streckholzer, U.3
Ungethum, U.4
Kenney, J.5
Trentz, O.6
Ertel, W.7
-
12
-
-
0025748883
-
Dysregulation of in vitro cytokine production by monocytes during sepsis
-
Munoz C, Carlet J, Fitting C, Misset B, Blériot JP, and Cavaillon JM: Dysregulation of in vitro cytokine production by monocytes during sepsis. J Clin Invest 88:1747-1754, 1991.
-
(1991)
J Clin Invest
, vol.88
, pp. 1747-1754
-
-
Munoz, C.1
Carlet, J.2
Fitting, C.3
Misset, B.4
Blériot, J.P.5
Cavaillon, J.M.6
-
13
-
-
0028937425
-
Downregulation of proinflammatory cytokine release in whole blood from sepsis patients
-
Ertel W, Kremer JP, Kenney J, Steckholzer U, Jarrar D, Trentz O, Schildberg FW: Downregulation of proinflammatory cytokine release in whole blood from sepsis patients. Blood 85:1341-1347, 1995.
-
(1995)
Blood
, vol.85
, pp. 1341-1347
-
-
Ertel, W.1
Kremer, J.P.2
Kenney, J.3
Steckholzer, U.4
Jarrar, D.5
Trentz, O.6
Schildberg, F.W.7
-
14
-
-
0032931385
-
The extent of traumatic damage determines a graded depression of the endotoxin responsiveness of peripheral mononuclear cells from patients with blunt trauma
-
in press
-
Majetschak M, Flach R, Jennissen V, Kreuzfelder E, Heukamp T, Neudeck F, Obertacke U, Schmit-Neuerburg KP, Schade FU: The extent of traumatic damage determines a graded depression of the endotoxin responsiveness of peripheral mononuclear cells from patients with blunt trauma. Crit Care Med, 1998 in press.
-
(1998)
Crit Care Med
-
-
Majetschak, M.1
Flach, R.2
Jennissen, V.3
Kreuzfelder, E.4
Heukamp, T.5
Neudeck, F.6
Obertacke, U.7
Schmit-Neuerburg, K.P.8
Schade, F.U.9
-
15
-
-
0026538855
-
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF): Receptor biology, signal transduction, and neutrophil activation
-
Rapoport AP, Abboud CN, DiPersio JF: Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF): receptor biology, signal transduction, and neutrophil activation. Blood Rev 6:43-57, 1992.
-
(1992)
Blood Rev
, vol.6
, pp. 43-57
-
-
Rapoport, A.P.1
Abboud, C.N.2
Dipersio, J.F.3
-
16
-
-
0029034238
-
IFNγ priming of monocytes enhances LPS-induced TNF production by augmenting both transcription and MRNA stability
-
Hayes MP, Freeman SL, Donnelly RP: IFNγ priming of monocytes enhances LPS-induced TNF production by augmenting both transcription and MRNA stability. Cytokine 7:427-435, 1995.
-
(1995)
Cytokine
, vol.7
, pp. 427-435
-
-
Hayes, M.P.1
Freeman, S.L.2
Donnelly, R.P.3
-
17
-
-
0029072988
-
Administration of rHuGM-CSF activates monocyte reactive oxygen species secretion and adhesion molecule expression in vivo in patients following high-dose chemotherapy
-
Williams MA, Kelsey SM, Collins PW, Gutteridge CN, Newland AC: Administration of rHuGM-CSF activates monocyte reactive oxygen species secretion and adhesion molecule expression in vivo in patients following high-dose chemotherapy. Br J Haematol 90:31-40, 1995.
-
(1995)
Br J Haematol
, vol.90
, pp. 31-40
-
-
Williams, M.A.1
Kelsey, S.M.2
Collins, P.W.3
Gutteridge, C.N.4
Newland, A.C.5
-
19
-
-
0023622888
-
Effects of recombinant human granulocyte and macrophage colony-stimulating factors on signal transduction pathways in human granulocytes
-
Sullivan R, Griffin JD, Simons ER, Schafer AI, Meshulam T, Fredette JP, Maas AK, Gadenne A, Leavitt JL, Melnick DA: Effects of recombinant human Granulocyte and Macrophage Colony-Stimulating Factors on signal transduction pathways in human granulocytes. J Immunol 139:3422-3430, 1987.
-
(1987)
J Immunol
, vol.139
, pp. 3422-3430
-
-
Sullivan, R.1
Griffin, J.D.2
Simons, E.R.3
Schafer, A.I.4
Meshulam, T.5
Fredette, J.P.6
Maas, A.K.7
Gadenne, A.8
Leavitt, J.L.9
Melnick, D.A.10
-
20
-
-
0031569105
-
In vitro prevention and reversal of lipopolysaccharide desensitization by IFNγ, IL-12, and granulocyte-macrophage colony-stimulating factor
-
Randow F, Döcke WD, Bundschuh DS, Hartung T, Wendel A, and Volk HD: In vitro prevention and reversal of lipopolysaccharide desensitization by IFNγ, IL-12, and granulocyte-macrophage colony-stimulating factor. J Immunol 158:2911-2918, 1997.
-
(1997)
J Immunol
, vol.158
, pp. 2911-2918
-
-
Randow, F.1
Döcke, W.D.2
Bundschuh, D.S.3
Hartung, T.4
Wendel, A.5
Volk, H.D.6
-
21
-
-
0026740918
-
Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor
-
Lieschke GJ, Burgees AW: Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor. N Engl J Med 327:28-35, 1992.
-
(1992)
N Engl J Med
, vol.327
, pp. 28-35
-
-
Lieschke, G.J.1
Burgees, A.W.2
-
22
-
-
0015962447
-
The injury severity score: A method for describing patients with multiple injuries and evaluating emergency care
-
Baker SP, O'Neill B, Haddon W, Long W: The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma 14:187-196, 1974.
-
(1974)
J Trauma
, vol.14
, pp. 187-196
-
-
Baker, S.P.1
O'Neill, B.2
Haddon, W.3
Long, W.4
-
23
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM consensus conference committee
-
American College of Chest Physicians/Society of Critical Care Medicine
-
Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 101:1644-1655, 1992.
-
(1992)
Chest
, vol.101
, pp. 1644-1655
-
-
Bone, R.C.1
Balk, R.A.2
Cerra, F.B.3
Dellinger, R.P.4
Fein, A.M.5
Knaus, W.A.6
Schein, R.M.7
Sibbald, W.J.8
-
24
-
-
0020074254
-
Causes of death after blunt trauma
-
Goris RJA, Draaisma J: Causes of death after blunt trauma. J Trauma 22:141-146, 1982.
-
(1982)
J Trauma
, vol.22
, pp. 141-146
-
-
Goris, R.J.A.1
Draaisma, J.2
-
25
-
-
0029848463
-
Endotoxin tolerance after severe injury and its regulatory mechanisms
-
Keel M, Schregenberger N, Steckholzer U, Ungethum U, Kenney J, Trentz O, Ertel W: Endotoxin tolerance after severe injury and its regulatory mechanisms. J Trauma 41:430-437, 1996.
-
(1996)
J Trauma
, vol.41
, pp. 430-437
-
-
Keel, M.1
Schregenberger, N.2
Steckholzer, U.3
Ungethum, U.4
Kenney, J.5
Trentz, O.6
Ertel, W.7
-
26
-
-
0029032458
-
Reduced tumor necrosis factor production in endotoxin-spiked whole blood after trauma: Experimental results and clinical correlation
-
Fabian TC, Croce MA, Fabian MJ, Trenthem LL, Yockey JM, Boscarino R, Proctor KG: Reduced tumor necrosis factor production in endotoxin-spiked whole blood after trauma: experimental results and clinical correlation. Surgery 118:63-72, 1995.
-
(1995)
Surgery
, vol.118
, pp. 63-72
-
-
Fabian, T.C.1
Croce, M.A.2
Fabian, M.J.3
Trenthem, L.L.4
Yockey, J.M.5
Boscarino, R.6
Proctor, K.G.7
-
27
-
-
0030726308
-
Response of the cellular immune system to cardiopulmonary bypass in vivo
-
Misoph M, Babin-Ebell J, Schwender S, Grossmann R, Keller F, Elert O: Response of the cellular immune system to cardiopulmonary bypass in vivo. Thorac Cardiovasc Surg 45: 217-223, 1997.
-
(1997)
Thorac Cardiovasc Surg
, vol.45
, pp. 217-223
-
-
Misoph, M.1
Babin-Ebell, J.2
Schwender, S.3
Grossmann, R.4
Keller, F.5
Elert, O.6
-
28
-
-
0005441766
-
Evidence of a circulating cytokine synthesis inhibitor during cardiopulmonary bypass
-
Börgermann J, Friedrich I, Feldt T, Reidemeister JC, Schade FU: Evidence of a circulating cytokine synthesis inhibitor during cardiopulmonary bypass. Shock 7:403, 1997.
-
(1997)
Shock
, vol.7
, pp. 403
-
-
Börgermann, J.1
Friedrich, I.2
Feldt, T.3
Reidemeister, J.C.4
Schade, F.U.5
-
29
-
-
0027996241
-
Mechanism of enhanced susceptibility to sepsis following hemorrhage. Interleukin-10 suppression of T-cell response is mediated by eicosanoid-induced interleukin-4 release
-
Ayala A, Lehman DL, Herdon CD, Chaudry IH: Mechanism of enhanced susceptibility to sepsis following hemorrhage. Interleukin-10 suppression of T-cell response is mediated by eicosanoid-induced interleukin-4 release. Arch Surg 129:1172-1178, 1994.
-
(1994)
Arch Surg
, vol.129
, pp. 1172-1178
-
-
Ayala, A.1
Lehman, D.L.2
Herdon, C.D.3
Chaudry, I.H.4
-
30
-
-
0039214495
-
Relation of ex vivo stimulated cytokine synthesis to posttraumatic sepsis
-
in press
-
Flach R, Majetschak M, Heukamp T, Jennissen V, Flohé S, Börgermann J, Obertacke U, Schade FU: Relation of ex vivo stimulated cytokine synthesis to posttraumatic sepsis. Cytokine, 1998 in press.
-
(1998)
Cytokine
-
-
Flach, R.1
Majetschak, M.2
Heukamp, T.3
Jennissen, V.4
Flohé, S.5
Börgermann, J.6
Obertacke, U.7
Schade, F.U.8
-
31
-
-
0030917203
-
Monocyte deactivation in sepsis patients: Restoration by IFNγ treatment
-
Döcke WD, Randow F, Syrbe U, Krausch D, Asadullah K, Reinke P, Volk HD, Kox W: Monocyte deactivation in sepsis patients: restoration by IFNγ treatment. Nat Med 3:678-681, 1997.
-
(1997)
Nat Med
, vol.3
, pp. 678-681
-
-
Döcke, W.D.1
Randow, F.2
Syrbe, U.3
Krausch, D.4
Asadullah, K.5
Reinke, P.6
Volk, H.D.7
Kox, W.8
-
32
-
-
0023943626
-
Human granulocyte-monocyte colony-stimulating factor and interleukin 3 stimulate monocyte cytotoxicity through a tumor necrosis factor-dependent mechanism
-
Cannistra SA, Vellenga E, Groshek P, Rambaldi A, Griffin JD: Human granulocyte-monocyte colony-stimulating factor and interleukin 3 stimulate monocyte cytotoxicity through a tumor necrosis factor-dependent mechanism. Blood 73: 672-676, 1988.
-
(1988)
Blood
, vol.73
, pp. 672-676
-
-
Cannistra, S.A.1
Vellenga, E.2
Groshek, P.3
Rambaldi, A.4
Griffin, J.D.5
-
33
-
-
0027312592
-
Priming of human monocytes for enhanced lipopolysaccharide responses: Expression of alpha interferon, interferon regulatory factors, and tumor necrosis factor
-
Hayes MP, Zoon KC: Priming of human monocytes for enhanced lipopolysaccharide responses: expression of alpha interferon, interferon regulatory factors, and tumor necrosis factor. Infect Immun 61:3222-3227, 1993.
-
(1993)
Infect Immun
, vol.61
, pp. 3222-3227
-
-
Hayes, M.P.1
Zoon, K.C.2
-
34
-
-
0024563994
-
Recombinant human granulocyte/macrophage colony-stimulating factor enhances monocyte cytotoxicity and secretion of tumor necrosis factor and interferon in cancer patients
-
Wing EJ, Magee DM, Whiteside TL, Kaplan SS, Shaduck RK: Recombinant human granulocyte/macrophage colony-stimulating factor enhances monocyte cytotoxicity and secretion of tumor necrosis factor and interferon in cancer patients. Blood 73:643-646, 1989.
-
(1989)
Blood
, vol.73
, pp. 643-646
-
-
Wing, E.J.1
Magee, D.M.2
Whiteside, T.L.3
Kaplan, S.S.4
Shaduck, R.K.5
-
35
-
-
0024577605
-
Granulocyte-macrophage colony-stimulating factor indues cytokine secretion by human polymorphonuclear leukocytes
-
Lindemann A, Riedel D, Oster W, Ziegler-Heitbrock HWL, Mertelsmann R, Herrmann F: granulocyte-macrophage colony-stimulating factor indues cytokine secretion by human polymorphonuclear leukocytes. J Clin Invest 83:1308-1312, 1989.
-
(1989)
J Clin Invest
, vol.83
, pp. 1308-1312
-
-
Lindemann, A.1
Riedel, D.2
Oster, W.3
Ziegler-Heitbrock, H.W.L.4
Mertelsmann, R.5
Herrmann, F.6
-
36
-
-
0025282043
-
Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at seperate points in signaling pathway
-
Han J, Thompson P, Beutler B: Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at seperate points in signaling pathway. J Exp Med 172:391-394, 1990.
-
(1990)
J Exp Med
, vol.172
, pp. 391-394
-
-
Han, J.1
Thompson, P.2
Beutler, B.3
-
37
-
-
0023700112
-
Granulocyte-macrophage colony-stimulating factor activates macrophages derived from bone marrow cultures to synthesis of MHCII molecules and to augment antigen presentation function
-
Fischer HG, Frosch S, Reske K, Reske-Kunz AB: granulocyte-macrophage colony-stimulating factor activates macrophages derived from bone marrow cultures to synthesis of MHCII molecules and to augment antigen presentation function. J Immunol 141:3882-3888, 1988.
-
(1988)
J Immunol
, vol.141
, pp. 3882-3888
-
-
Fischer, H.G.1
Frosch, S.2
Reske, K.3
Reske-Kunz, A.B.4
-
38
-
-
0023769976
-
Depressed interferon gamma production and monocyte HLA-DR expression after severe injury
-
Livingston DH, Appel SH, Wellhausen SR, Sonnenfeld G, Polk HC: Depressed interferon gamma production and monocyte HLA-DR expression after severe injury. Arch Surg 123:1309-1312, 1988.
-
(1988)
Arch Surg
, vol.123
, pp. 1309-1312
-
-
Livingston, D.H.1
Appel, S.H.2
Wellhausen, S.R.3
Sonnenfeld, G.4
Polk, H.C.5
-
40
-
-
0029963961
-
Interleukin-10 is associated with the development of sepsis in trauma patients
-
Sherry RM, Cue JI, Goddard JK, Parramore JB, DiPiro JT: Interleukin-10 is associated with the development of sepsis in trauma patients. J Trauma 40:613-616, 1996.
-
(1996)
J Trauma
, vol.40
, pp. 613-616
-
-
Sherry, R.M.1
Cue, J.I.2
Goddard, J.K.3
Parramore, J.B.4
DiPiro, J.T.5
-
41
-
-
0029823055
-
Monocyte deactivation: Rationale for a new therapeutic strategy in sepsis
-
Volk HD, Reinke P, Krausch D, Zuckermann H, Asadullah K, Muller JM, Döcke WD, Kox WJ: Monocyte deactivation: rationale for a new therapeutic strategy in sepsis. Intensive Care Med 22 Suppl 4:S474-81, 1996.
-
(1996)
Intensive Care Med
, vol.22
, Issue.SUPPL. 4
-
-
Volk, H.D.1
Reinke, P.2
Krausch, D.3
Zuckermann, H.4
Asadullah, K.5
Muller, J.M.6
Döcke, W.D.7
Kox, W.J.8
-
42
-
-
0025915209
-
Eicosanoids regulate tumor necrosis factor synthesis after hemorrhage in vitro and in vivo
-
Ertel W, Morrison MH, Ayala A, Chaudry IH: Eicosanoids regulate tumor necrosis factor synthesis after hemorrhage in vitro and in vivo. J Trauma 31:609-615, 1991.
-
(1991)
J Trauma
, vol.31
, pp. 609-615
-
-
Ertel, W.1
Morrison, M.H.2
Ayala, A.3
Chaudry, I.H.4
-
43
-
-
0028892027
-
Clinical toxicity of cytokines used as haemopoietic growth factors
-
Vial T, Descotes J: Clinical toxicity of cytokines used as haemopoietic growth factors. Drug Saf 13:371-406, 1995.
-
(1995)
Drug Saf
, vol.13
, pp. 371-406
-
-
Vial, T.1
Descotes, J.2
|