Labeled carcinoembryonic antigen antibodies excitable by infrared rays: A novel diagnostic method for micro cancers in the digestive tract

Internal Medicine

Volumn 38, Issue 7, 1999, Pages 537-542

  Muguruma, Naoki ^b   Ito, Susumu ^f   Bando, Terumi ^f   Taoka, Satoko ^f   Kusaka, Yoshihiro ^f   Hayashi, Shigehito ^f   Ichikawa, Soichi ^f   Matsunaga, Yuko ^f   Tada, Yoshie ^f   Okamura, Seisuke ^a   Ii, Kunio ^b   Imaizumi, Katsuichi ^f   Nakamura, Kazunari ^c   Takesako, Kazuhiro ^d   Shibamura, Seiichi ^e  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c OLYMPUS CORPORATION   (Japan)

^d Dojindo Laboratories   (Japan)

^e DAIICHI PURE CHEMICALS CO LTD   (Japan)

^f NONE

Author keywords

Immunofluorescence; Infrared ray fluorescence; Infrared ray microscope; Labeled monoclonal antibody

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; DIAGNOSTIC AGENT; DRUG DERIVATIVE; FLUORESCENT DYE; INDOCYANINE GREEN; INDOCYANINE GREEN SULFO OSU; INDOCYANINE GREEN-SULFO-OSU; MONOCLONAL ANTIBODY; PARAFFIN;

ADENOCARCINOMA; ANIMAL; ARTICLE; COLON TUMOR; CROSS REACTION; FLUORESCENCE MICROSCOPY; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; INFRARED RADIATION; INSTRUMENTATION; METABOLISM; MOUSE;

ADENOCARCINOMA; ANIMALS; ANTIBODIES, MONOCLONAL; CARCINOEMBRYONIC ANTIGEN; COLONIC NEOPLASMS; CROSS REACTIONS; FLUORESCENT DYES; HUMANS; IMMUNOHISTOCHEMISTRY; INDOCYANINE GREEN; INFRARED RAYS; MICE; MICROSCOPY, FLUORESCENCE; PARAFFIN EMBEDDING;

EID: 0033158799     PISSN: 09182918     EISSN: None     Source Type: Journal    
DOI: 10.2169/internalmedicine.38.537     Document Type: Article

References (14)

1. Paganelli G, Malcovati M, Fazio F. Monoclonal antibody pretargetting techniques for tumour localization: avidin-biotin system. International Workshop on Techniques for Amplification of Tumour Targetting. Nucl Med Commun 12: 211-234, 1991.
2. Patt YZ, Podoloff DA, Curley S, et al. Monoclonal antibody imaging in patients with colorectal cancer increasing levels of serum carcinoembryonic antigen. Experience with ZCE-025 and IMMU-4 monoclonal antibodies and proposed directions for clinical trials. Cancer 71: 4293-4297, 1993.
3. Pelegrin A, Folli S, Buchegger F, et al. Antibody fluorescein conjugates for photoimmunodiagnosis of human colon carcinoma in nude mice. Cancer 67: 2529-2537, 1991.
4. Keller R, Winde G, Eisenhawer C, et al. Immunoscopy-a technique combining endoscopy and immunofluorescence for diagnosis of colorectal carcinoma. Gastrointest Endosc 47: 154-161, 1998.
5. Tatsuta M, Iishi H, Ichii M, et al. Diagnosis of gastric cancers with fluorescein-labeled monoclonal antibodies to carcinoembryonic antigen. Lasers Surg Med 9: 422-426, 1989.
6. Davies RJ. Ultraviolet radiation damage in DNA. Biochem Soc Trans 23: 407-418, 1995.
7. Williams RJ, Narayanan N, Casay GA, et al. Instrument to detect near-infrared fluorescence in solid-phase immunoassay. Anal Chem 66: 3102-3107, 1994.
8. Ito S, Muguruma N, Kakehashi Y, et al. Development of fluorescence-emitting antibody labeling substance by near-infrared ray excitation. Bioorg Med Chem Letters 5: 2689-2694, 1995.
9. Muguruma N, Ito S, Hayashi S, et al. Antibodies labeled with fluorescence-agent excitable by infrared rays. J Gastroenterol 33: 467-461, 1998.
10. Leevy CM, Stein SW, Cherrick GR, et al. Indocyanine green clearance: A test of liver excretory function. Clin Res 7: 290-296, 1959.
11. Mordon S, Devoisselle JM, Soulie-Begu-S, et al. Indocyanine green: physiochemical factors affecting its fluorescence in vivo. Microvasc Res 55: 146-152, 1998.
12. Ito S, Muguruma N, Hayashi S, et al. Development of an imaging system using fluorescent labeling substances excited by infrared rays. Dig Endosc 9: 278-282, 1997.
13. Ito S, Muguruma N, Hayashi S, et al. Development of agents for reinforcement of fluorescence on near-infrared ray excitation for immuhistological staining. Bioorg Med Chem 6: 613-618, 1998.
14. Heatley NG. Mucosubstance as a barrier to diffusion. Gastroenterology 37: 313-317, 1959.