Involvement of the Ink4a gene (p16 and p19arf) in murine tumorigenesis

International Journal of Oncology

Volumn 15, Issue 1, 1999, Pages 17-24

  Cordón Cardó, Carlos ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Murine tumorigenesis; P16 gene; P19arf gene

Indexed keywords

DNA; PROTEIN; PROTEIN P14ARF; PROTEIN P16INK4A; RETINOBLASTOMA PROTEIN;

ANIMAL; ARTICLE; CELL CYCLE; CHEMICALLY INDUCED DISORDER; EXPERIMENTAL NEOPLASM; GENE DELETION; GENE TARGETING; GENETIC PREDISPOSITION; GENETICS; HETEROZYGOTE; MOUSE; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE;

ANIMALS; CELL CYCLE; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA, NEOPLASM; GENE DELETION; GENE TARGETING; GENES, P16; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; MICE; MICE, KNOCKOUT; NEOPLASMS, EXPERIMENTAL; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROTEINS; RETINOBLASTOMA PROTEIN; TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 0033158620     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (2)

1. Kamb A, Gruis N, Weaver-Feldhaus J, Liu Q, Harshman K, Tavtigian SV, Stockert E, Day RS III, Johnson BE and Skolnick MH: A cell cycle regulator potentially involved in genesis of many tumor types. Science 264: 436-440, 1994.
2. Nobori T, Miura K, Wu DJ, Lois A, Takabayashi K and Carson DA: Deletions of the cyclin-dependent kinase 4 inhibitor gene in multiple human cancers. Nature 368: 753-756, 1994.