Increases in the threshold for the development of epileptiform activity in field CA1 of Krushinskii-Molodnika rat hippocampal slices as an adaptive protective mechanism

Neuroscience and Behavioral Physiology

Volumn 29, Issue 4, 1999, Pages 467-474

  Sem'yanov, A V ^a   Morenkov, E D ^b   Kalemenev, S V ^a   Yaroshenko, V P ^a   Godukhin, O V ^a  

^a INSTITUTE OF THEORETICAL AND EXPERIMENTAL BIOPHYSICS   (Russian Federation)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

Audiogenic convulsions; Field CA1 of hippocampal slices; Field EPSP; In vitro kindling like state; Population spike

Indexed keywords

ADAPTATION; ANIMAL; ARTICLE; AUDITORY STIMULATION; EPILEPSY; EVOKED RESPONSE; GENETICS; HIPPOCAMPUS; IN VITRO STUDY; LONG TERM POTENTIATION; NERVE CELL NETWORK; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; RAT STRAIN; SEIZURE; SYNAPTIC TRANSMISSION; WISTAR RAT;

ACOUSTIC STIMULATION; ADAPTATION, PHYSIOLOGICAL; ANIMALS; EPILEPSY; EVOKED POTENTIALS; HIPPOCAMPUS; LONG-TERM POTENTIATION; NERVE NET; RATS; RATS, INBRED STRAINS; RATS, WISTAR; SEIZURES; SYNAPTIC TRANSMISSION;

EID: 0033155286     PISSN: 00970549     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02461087     Document Type: Article

References (16)

1. N. A. Veretennikov, D. A. Kulikova, V. M. Panin, and L. I. Korochkin, "Biological aspects of epilepsy: morphological and molecular studies of audiogenic epilepsy," Uspehkhi Sovrem. Biol., 116, No. 4, 401-417 (1996).
2. + in field CA1 of the rat hippocampus," Ros. Fiziol. Zh. im. I. M. Sechenova, 83, No. 8, 14-23 (1997).
3. G. V. Goddard, D. C. McIntyre, and C. K. Leech, "A permanent change in brain function resulting from daily electrical stimulation," Exp. Neurology, 15, 295-330 (1969).
4. G. C. Faas, M. Breugdenhill, and W. J. Wadman, "Calcium currents in pyramidal CA1 neurons in vitro after kindling epileptogenesis in the hippocampus of the rat," Neurosci., 75, No. 1, 57-67 (1996).
5. U. Heineman, H. Beck, J. P. Dreier, E. Picker, J. Stabel, and C. C. Zhang, "The dentate gyrus as a regulated gate for the propagation of epileptiform activity," Epilepsy Res., 7, 27-280 (1992).
6. P. C. Jobe, "Pharmacology of audiogenic seizures," in: The Pharmacology of Hearing. Experimental and Clinical Bases, R. D. Brown and E. A. Diagneault (Eds.), Wiley Intersci., New York (1981), pp. 271-304.
7. 2+-induced CA1 burst activity in rat hippocampal slices," Brain Res., 723, 196-198.
8. E. W. Lothmann and J. M. Williamson, "Closely spaced recurrent hippocampal seizures elicit two types of heightened epileptogenesis: a rapidly developing, transient kindling and slowly developing, enduring kindling," Brain Res., 649, 71-84 (1994).
9. J. L. Meyerhoff, M. B. Robinson, K. J. Koller, M. A. Bixler, and J. T. Coyle, "Kindling increases brain levels of NAAG and seizures reduce activity of a NAAG-hydrolyzing enzyme NAALADase," Epilepsy Res., 8, 297-396 (1992).
10. K. Morimoto and M. Sato, "NMDA receptor complex and kindling mechanisms," Epilepsy Res., 9, 297-305 (1992).
11. A. Nehlig, A. Pereira de Vasconcelos, M. Vergenes, S. Boyet, and C. Marescaux, "Interictal cerebral metabolic levels in Wistar rats sensitive to audiogenic seizures," Brain Res., 724, 97-102 (1996).
12. i needed to trigger LTD and LTP," Neuron, 16, 619-629 (1996).
13. J. C. Romaniva, Z. A. Zorina, and L. J. Korochkin, "A genetic, physiological and biochemical investigation of audiogenic seizures in rats," Behav. Genet., 23, 483-489 (1993).
14. A. Semyanov, E. Morenkov, and O. Godukhin, "The decreased susceptibility to the development of in vitro kindling-like state in hippocampal CA1 slice of rats sensitive to audiogenic seizures," Neurosci. Lett., 230, 187-190 (1997).
15. 2+ removals in Wistar CA1 hippocampal slices," Neurosci. Lett., in press (1998).
16. 2+-channels," Neurosci. Lett., 223, 177-180 (1977).