Effects of intragenic variability at 3 polymorphic sites of the apolipoprotein B gene on serum lipids and lipoproteins in a multiethnic Asian population

Human Biology

Volumn 71, Issue 3, 1999, Pages 381-397

  Choong, M L ^a   Sethi, S K ^a   Koay, E S C ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Chinese; Disease association; Genetic heterogeneity; Indians; Linkage disequilibrium; Malays; Singapore

Indexed keywords

ALLELE; APOLIPOPROTEIN B; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

EID: 0033152674     PISSN: 00187143     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Aburatani, H., A. Matsumoto, H. Itoh et al. 1988. A study of DNA polymorphism in the apolipoprotein B gene in a Japanese population. Atherosclerosis 72:71-76.
2. Boerwinkle, E., S.S. Lee, R. Butler et al. 1990. Rapid typing of the apolipoprotein B DNA polymorphisms by DNA amplification. Atherosclerosis 81:225-232.
3. Bøhn, M., and K. Berg. 1994. The XbaI polymorphism at the apolipoprotein B site and risk of atherosclerotic disease. Clin. Genet. 46:77-79.
4. Brown, M.S., and J.L. Goldstein. 1986. A receptor-mediated pathway for cholesterol homeostasis. Science 232:34-37.
5. Choong, M.L., E.S.C. Koay, M.C. Khaw et al. 1999. Apolipoprotein B 5′-Ins/Del and 3′-VNTR polymorphisms in Chinese, Malay, and Indian Singaporeans. Hum. Hered. 49:31-40.
6. Friedewald, W.T., R.I. Levy, and D.S. Fredrickson. 1972. Estimation of the concentration of low density lipoprotein cholesterol in plasma, without the use of the preparative ultracentrifuge. Clin. Chem. 18:499-502.
7. Friedlander, Y., N.A. Kaufmann, H. Cedar et al. 1993. The role of XbaI polymorphism of the apolipoprotein B gene in determining levels and covariability of lipid and lipoprotein variables in a sample of Israeli offspring with family history of myocardial infarction. Atherosclerosis 98:165-177.
8. Genest, J.J., J.M. Ordovas, J.R. McNamara et al. 1990. DNA polymorphisms of the apolipoprotein B gene in patients with premature coronary artery disease. Atherosclerosis 82:7-17.
9. Hansen, P.S., L.U. Gerdes, I.C. Klausen et al. 1993. Polymorphisms in the apolipoprotein B-100 gene contribute to normal variation in plasma lipid in 464 Danish men born in 1948. Hum. Genet. 91:45-50.
10. Hegele, R.A., L.S. Huang, P.N. Herbert et al. 1986. Apolipoprotein B gene polymorphisms associated with myocardial infarction. New Engl. J. Med. 315:1509-1515.
11. Humphries, S.E. 1988. DNA polymorphisms of the apolipoprotein genes: Their use in the investigation of the genetic component of hyperlipidemia and atherosclerosis. Atherosclerosis 72:89-108.
12. Innerarity, T.L., R.W. Mahley, K.H. Weisgraber et al. 1990. Familial defective apolipoprotein B-100: A mutation of the apolipoprotein B that causes hypercholesterolemia (review). J. Lipid Res. 31:1337-1349.
13. Juvonen, T., M.J. Savolainen, M.I. Kairaluoma et al. 1995. Polymorphisms of the apoB, apoA-I, and cholesteryl ester transfer protein gene sites in patients with gallbladder disease. J. Lipid Res. 36:804-812.
14. Law, A., L.M. Powell, N. Brunt et al. 1986. Common DNA polymorphism within coding sequence of apolipoprotein B gene: Association with altered lipid levels. Lancet 1:1301-1303.
15. Mendis, S., J. Shepherd, C.J. Packard et al. 1991. Restriction fragment length polymorphisms in the apoB gene in relation to coronary heart disease in a southern Asian population. Clin. Chim. Acta 196:107-117.
16. Miller, S.A., D.D. Dykes, and H.F. Polesky. 1988. A simple salting-out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16:1215.
17. Pan, J.P., A.N. Chiang, J.J. Tai et al. 1995. Restriction fragment length polymorphisms of apolipoprotein B gene in Chinese population with coronary heart disease. Clin. Chem. 41:424-429.
18. Paulweber, B., W. Friedl, E. Krempler et al. 1990. Association of DNA polymorphisms at the apoB gene site with coronary heart disease and serum very low density lipoprotein levels. Arteriosclerosis 10:17-24.
19. Peacock, R., A. Dunning, A. Hamsten et al. 1992. Apolipoprotein B polymorphisms, lipoproteins, and coronary atherosclerosis: A study of young myocardial infarction survivors and healthy population based individuals. Atherosclerosis 92:151-164.
20. Priestley, L., T. Knott, S. Wallis et al. 1985. RFLP for the human apolipoprotein B gene: I, BamHI; II. EcoRI; III, EcoRV; IV. MspI; V, XbaI. Nucleic Acids Res. 18:6789-6793.
21. Renges, H.H., R. Peacock, A.M. Dunning et al. 1992. Genetic relationship between the 3′-VNTR and diallelic apolipoprotein B gene polymorphisms: Haplotype analysis in individuals of European and South Asian origin. Ann. Hum. Genet. 56:11-33.
22. Saha, N., J.S.H. Tay, C.K. Heng et al. 1993. DNA polymorphisms of the apolipoprotein B gene are associated with obesity and serum lipids in healthy Indians in Singapore. Clin. Genet. 44:113-120.
23. Saha, N., M.C. Tong, J.S.H. Tay et al. 1992. DNA polymorphisms of the apolipoprotein B gene in Chinese coronary artery disease patients. Clin. Genet. 42:164-170.
24. Sambuugiin, N., V.N. Petrishchev, and I.U.G. Rychkov. 1991. DNA polymorphism in the Mongolian population: Restriction fragment length polymorphism analysis of DNA at seven loci of the nuclear genome. Genetika (MOSCOW) 27:2137-2142.
25. Stepanov, V.A., and V.P. Puzyrev. 1994. Apolipoprotein B gene polymorphism in a Russian population. Hum. Biol. 66:527-531.
26. Talmud, P.J., N. Barni, A.M. Kessling et al. 1987. Apolipoprotein B gene variants are involved in the determination of serum cholesterol levels: A study in normo- and hyperlipidemic individuals. Atherosclerosis 67:81-89.
27. Terwilliger, J.D., and J. Ott. 1994. Handbook of Human Genetic Linkage. Baltimore, MD: Johns Hopkins University Press.
28. Tybjærg-Hansen, A., B.C. Nordesgaard, L.U. Gerdes et al. 1991. Variation of apolipoprotein B gene is associated with myocardial infarction and lipoprotein levels in Danes. Atherosclerosis 89:69-81.
29. Vilella, E., J. Balanya, L. Masana et al. 1992. Low density lipoprotein ligand-receptor interactions in normal healthy individuals characterized by their XbaI apolipoprotein B DNA polymorphism. Atherosclerosis 93:145-153.
30. Visvikis, S., J.P. Cambou, D. Arveiler et al. 1993. Apolipoprotein B signal peptide polymorphisms in patients with myocardial infarction and controls. Hum. Genet. 90:561-565.