-
1
-
-
0027945342
-
Discrimination of molecular signals by the olfactory receptor neuron
-
Shepherd GM: Discrimination of molecular signals by the olfactory receptor neuron. Neuron 1994, 13:771-790.
-
(1994)
Neuron
, vol.13
, pp. 771-790
-
-
Shepherd, G.M.1
-
2
-
-
0029939849
-
Information coding in the vertebrate olfactory system
-
Buck LB: Information coding in the vertebrate olfactory system. Annu Rev Neurosci 1996, 19:517-544.
-
(1996)
Annu Rev Neurosci
, vol.19
, pp. 517-544
-
-
Buck, L.B.1
-
3
-
-
0031043834
-
Mechanisms of olfactory discrimination: Converging evidence for common principles across phyla
-
Hildebrand JG, Shepherd GM: Mechanisms of olfactory discrimination: Converging evidence for common principles across phyla. Annu Rev Neurosci 1997, 20:595-631.
-
(1997)
Annu Rev Neurosci
, vol.20
, pp. 595-631
-
-
Hildebrand, J.G.1
Shepherd, G.M.2
-
4
-
-
0025825726
-
A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
-
Buck L, Axel R: A novel multigene family may encode odorant receptors: A molecular basis for odor recognition. Cell 1991, 65:175-187.
-
(1991)
Cell
, vol.65
, pp. 175-187
-
-
Buck, L.1
Axel, R.2
-
5
-
-
0032894070
-
Olfactory receptor database: A database of the largest eukaryotic gene family
-
Skoufos E, Healy MD, Singer MS, Nadkarni PM, Miller PL, Shepherd GM: Olfactory receptor database: A database of the largest eukaryotic gene family. Nucleic Acids Res 1999, 27:343-345. OR sequences are collected in a user-friendly format in the olfactory Receptor Database, which is accessible on the World Wide Web at http://crepe.med.yale.edu/ORDB/HTML
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 343-345
-
-
Skoufos, E.1
Healy, M.D.2
Singer, M.S.3
Nadkarni, P.M.4
Miller, P.L.5
Shepherd, G.M.6
-
6
-
-
0032965527
-
Molecular biology of odorant receptors in vertebrates
-
Mombaerts P: Molecular biology of odorant receptors in vertebrates. Annu Rev Neurosci 1999, 22:487-509. A general review of ORs, with emphasis on information from experimental vertebrate species such as mouse, rat, and zebrafish.
-
(1999)
Annu Rev Neurosci
, vol.22
, pp. 487-509
-
-
Mombaerts, P.1
-
7
-
-
0001263817
-
Olfactory receptors
-
Lancet D, Ben-Arie N : Olfactory receptors. Curr Biol 1993, 3:668-674.
-
(1993)
Curr Biol
, vol.3
, pp. 668-674
-
-
Lancet, D.1
Ben-Arie, N.2
-
8
-
-
0030046045
-
The chromosomal distribution of mouse odorant receptor genes
-
Sullivan SL, Adamson MC, Ressler KJ, Kozak CA, Buck LB: The chromosomal distribution of mouse odorant receptor genes. Proc Natl Acad Sci USA 1996, 93:884-888.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 884-888
-
-
Sullivan, S.L.1
Adamson, M.C.2
Ressler, K.J.3
Kozak, C.A.4
Buck, L.B.5
-
9
-
-
0031883174
-
Distribution of olfactory receptor genes in the human genome
-
Rouiquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D: Distribution of olfactory receptor genes in the human genome. Nat Genet 1998, 18:243-250. This is the most comprehensive analysis of the human OR gene repertoire published to date. Between 25-53 genomic sites were identified by FISH. 72% of isolated partial OR sequences are from pseudogenes.
-
(1998)
Nat Genet
, vol.18
, pp. 243-250
-
-
Rouiquier, S.1
Taviaux, S.2
Trask, B.J.3
Brand-Arpon, V.4
Van Den Engh, G.5
Demaille, J.6
Giorgi, D.7
-
10
-
-
0026877347
-
The olfactory multigene family
-
Buck LB: The olfactory multigene family. Curr Biol 1992, 2:467-473.
-
(1992)
Curr Biol
, vol.2
, pp. 467-473
-
-
Buck, L.B.1
-
11
-
-
0026501379
-
Novel G-protein-coupled receptors: A gene family of putative human olfactory receptor sequences
-
Selbie LA, Townsend-Nicholson A, Iismaa TP, Shine J: Novel G-protein-coupled receptors: A gene family of putative human olfactory receptor sequences. Mol Brain Res 1992, 13:159-163.
-
(1992)
Mol Brain Res
, vol.13
, pp. 159-163
-
-
Selbie, L.A.1
Townsend-Nicholson, A.2
Iismaa, T.P.3
Shine, J.4
-
12
-
-
0026502241
-
Expression of members of the putative olfactory receptor gene family in mammalian germ cells
-
Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gérard C, Perret J et al.: Expression of members of the putative olfactory receptor gene family in mammalian germ cells. Nature 1992, 355:453-455.
-
(1992)
Nature
, vol.355
, pp. 453-455
-
-
Parmentier, M.1
Libert, F.2
Schurmans, S.3
Schiffmann, S.4
Lefort, A.5
Eggerickx, D.6
Ledent, C.7
Mollereau, C.8
Gérard, C.9
Perret, J.10
-
13
-
-
0028069247
-
Olfactory receptor gene cluster on human chromosome 17: Possible duplication of an ancestral receptor repertoire
-
Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K, Sheer D, Lehrach H, North MA: Olfactory receptor gene cluster on human chromosome 17: Possible duplication of an ancestral receptor repertoire. Hum Mol Genet 1994, 3:229-235.
-
(1994)
Hum Mol Genet
, vol.3
, pp. 229-235
-
-
Ben-Arie, N.1
Lancet, D.2
Taylor, C.3
Khen, M.4
Walker, N.5
Ledbetter, D.H.6
Carrozzo, R.7
Patel, K.8
Sheer, D.9
Lehrach, H.10
North, M.A.11
-
14
-
-
0030588152
-
Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: Recombinatorial events affecting receptor diversity
-
Glusman G, Clifton S, Roe B, Lancet D: Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: Recombinatorial events affecting receptor diversity. Genomics 1996, 37:147-160.
-
(1996)
Genomics
, vol.37
, pp. 147-160
-
-
Glusman, G.1
Clifton, S.2
Roe, B.3
Lancet, D.4
-
15
-
-
0027287270
-
The OLFR1 gene encoding the HGMPO7E putative olfactory receptor maps to the 17p13→p12 region of the human genome and reveals an mspl restriction fragment length polymorphism
-
Schurmans S, Muscatelli F, Miot F, Mattei MG, Vassart G: The OLFR1 gene encoding the HGMPO7E putative olfactory receptor maps to the 17p13→p12 region of the human genome and reveals an mspl restriction fragment length polymorphism. Cytogenet Cell Genet 1993, 63:200-204.
-
(1993)
Cytogenet Cell Genet
, vol.63
, pp. 200-204
-
-
Schurmans, S.1
Muscatelli, F.2
Miot, F.3
Mattei, M.G.4
Vassart, G.5
-
16
-
-
6844242311
-
Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes
-
Trask BJ, Friedman C, Martin-Gallardo A, Rowen L, Akinbami C, Blankenship J, Collins C, Giorgi D, Iadonato S, Johnson F et al: Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes. Hum Mol Genet 1998, 7:13-26. A sequence of 36 kb contains three OR-like sequences, one of which may be functional. This 36 kb block is repeated polymorphically at various subtelomeric sites. This is an unususal case of genomic variation.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 13-26
-
-
Trask, B.J.1
Friedman, C.2
Martin-Gallardo, A.3
Rowen, L.4
Akinbami, C.5
Blankenship, J.6
Collins, C.7
Giorgi, D.8
Iadonato, S.9
Johnson, F.10
-
17
-
-
0032191174
-
Organization and evolution of olfactory receptor genes on human chromosome 11
-
Buettner JA, Glusman G, Ben-Arie N, Ramos P, Lancet D, Evans GA: Organization and evolution of olfactory receptor genes on human chromosome 11. Genomics 1998, 53:56-68. A total of 28 OR-like sequences are described in this report spread over seven regions on chromosome 11. Only seven (25%) may encode functional OR genes.
-
(1998)
Genomics
, vol.53
, pp. 56-68
-
-
Buettner, J.A.1
Glusman, G.2
Ben-Arie, N.3
Ramos, P.4
Lancet, D.5
Evans, G.A.6
-
18
-
-
0031659924
-
A gene recently inactivated in human defines a new olfactory receptor family in mammals
-
Rouquier S, Friedman C, Delettre C, van den Engh G, Blancher A, Crouau-Roy B, Trask BJ, Giorgi D: A gene recently inactivated in human defines a new olfactory receptor family in mammals. Hum Mol Genet 1998, 7:1337-1345.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1337-1345
-
-
Rouquier, S.1
Friedman, C.2
Delettre, C.3
Van Den Engh, G.4
Blancher, A.5
Crouau-Roy, B.6
Trask, B.J.7
Giorgi, D.8
-
19
-
-
0033557889
-
A genomic region encompassing a cluster of olfactory receptor genes and a myosin light chain kinase (MYLK) gene is duplicated on human chromosome regions 3q13-q21 and 3p13
-
Brand-Arpon V, Rouquier S, Massa H, de Jong PJ, Ferraz C, Ioannou PA, Demaille JG, Trask BJ, Giorgi D: A genomic region encompassing a cluster of olfactory receptor genes and a myosin light chain kinase (MYLK) gene is duplicated on human chromosome regions 3q13-q21 and 3p13. Genomics 1999, 56:98-110. A 250 kb genomic region reveals four OR pseudogenes. Additionally a pseudogene of myosin light chain kinase is in the immediate vicinity. This is the first example of a non-OR-like sequence embedded within or adjacent to an OR cluster.
-
(1999)
Genomics
, vol.56
, pp. 98-110
-
-
Brand-Arpon, V.1
Rouquier, S.2
Massa, H.3
De Jong, P.J.4
Ferraz, C.5
Ioannou, P.A.6
Demaille, J.G.7
Trask, B.J.8
Giorgi, D.9
-
20
-
-
7844234750
-
Large multi-chromosomal duplications encompass many members of the olfactory receptor gene family in the human genome
-
Trask BJ, Massa H, Brand-Arpon V, Chan K, Friedman C, Nguyen OT, Eichler E, van den Engh G, Rouquier S, Shizuya H, Giorgi D: Large multi-chromosomal duplications encompass many members of the olfactory receptor gene family in the human genome. Hum Mol Genet 1998, 7:2007-2020. A large-scale effort resulted in the isolation of 74 OR containing cosmids and BACs. Mapping by FISH revealed that many BACs hybridize at multiple sites. Intergenic regions apparently have extensive sequence homology with other regions in the genome which means that OR pseudogenes may not have arisen through retrotransposition but by divergence from duplicated clusters.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 2007-2020
-
-
Trask, B.J.1
Massa, H.2
Brand-Arpon, V.3
Chan, K.4
Friedman, C.5
Nguyen, O.T.6
Eichler, E.7
Van Den Engh, G.8
Rouquier, S.9
Shizuya, H.10
Giorgi, D.11
-
21
-
-
0029002299
-
Olfactory receptor-like genes are located in the human major histocompatibility comples
-
Fan W, Liu YC, Parimoo S, Weissman SM: Olfactory receptor-like genes are located in the human major histocompatibility comples. Genomics 1995, 27:119-1 23.
-
(1995)
Genomics
, vol.27
, pp. 119-123
-
-
Fan, W.1
Liu, Y.C.2
Parimoo, S.3
Weissman, S.M.4
-
22
-
-
0031033489
-
The evolution of mammalian olfactory receptor genes
-
Issel-Tarver L, Rine J: The evolution of mammalian olfactory receptor genes. Genetics 1997, 145:185-195.
-
(1997)
Genetics
, vol.145
, pp. 185-195
-
-
Issel-Tarver, L.1
Rine, J.2
-
23
-
-
0031834146
-
Location of mouse and human genes corresponding to conserved canine olfactory receptor gene families
-
Carver EA, Issel-Tarver L, Rine J, Olsen AS, Stubbs L: Location of mouse and human genes corresponding to conserved canine olfactory receptor gene families. Mamm Genome 1998, 9:349-354.
-
(1998)
Mamm Genome
, vol.9
, pp. 349-354
-
-
Carver, E.A.1
Issel-Tarver, L.2
Rine, J.3
Olsen, A.S.4
Stubbs, L.5
-
24
-
-
0030586949
-
A transcription map of the major histocompatibility complex (MHC) class I region
-
Gruen JR, Nalabolu SR, Chu TW, Bowlus C, Fan WF, Goei VL, Wei H, SivakamasundaRi R, Liu YC, Xu HX et al.: A transcription map of the major histocompatibility complex (MHC) class I region. Genomics 1996, 36:70-85.
-
(1996)
Genomics
, vol.36
, pp. 70-85
-
-
Gruen, J.R.1
Nalabolu, S.R.2
Chu, T.W.3
Bowlus, C.4
Fan, W.F.5
Goei, V.L.6
Wei, H.7
Sivakamasundari, R.8
Liu, Y.C.9
Xu, H.X.10
-
25
-
-
0030007375
-
Olfactory receptor-encoding genes and pseudogenes are expressed in humans
-
Crowe ML, Perry BN, Connerton IF: Olfactory receptor-encoding genes and pseudogenes are expressed in humans. Gene 1996, 169:247-249.
-
(1996)
Gene
, vol.169
, pp. 247-249
-
-
Crowe, M.L.1
Perry, B.N.2
Connerton, I.F.3
-
26
-
-
0027154580
-
A zonal organization of odorant receptor gene expression in the olfactory epithelium
-
Ressler KJ, Sullivan SL, Buck LB: A zonal organization of odorant receptor gene expression in the olfactory epithelium. Cell 1993, 73:597-609.
-
(1993)
Cell
, vol.73
, pp. 597-609
-
-
Ressler, K.J.1
Sullivan, S.L.2
Buck, L.B.3
-
27
-
-
0027328684
-
Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium
-
Vassar R, Ngai J, Axel R: Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium. Cell 1993, 74:309-318.
-
(1993)
Cell
, vol.74
, pp. 309-318
-
-
Vassar, R.1
Ngai, J.2
Axel, R.3
-
28
-
-
0028578697
-
Topographic organization of sensory projections to the olfactory bulb
-
Vassar R, Chao SK, Sitcheran R, Nuñez JM, Vosshall LB, Axel R: Topographic organization of sensory projections to the olfactory bulb. Cell 1994, 79:981 -991.
-
(1994)
Cell
, vol.79
, pp. 981-991
-
-
Vassar, R.1
Chao, S.K.2
Sitcheran, R.3
Nuñez, J.M.4
Vosshall, L.B.5
Axel, R.6
-
29
-
-
0028657579
-
Information coding in the olfactory system: Evidence for a stereotyped and highly organized epitope map in the olfactory bulb
-
Ressler KJ, Sullivan SL, Buck LB: Information coding in the olfactory system: Evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Cell 1994, 79:1245-1255.
-
(1994)
Cell
, vol.79
, pp. 1245-1255
-
-
Ressler, K.J.1
Sullivan, S.L.2
Buck, L.B.3
-
30
-
-
0030584078
-
Visualizing an olfactory sensory map
-
Mombaerts P, Wang F, Dulac C, Chao SK, Nemes A, Mendelsohn M, Edmondson J, Axel R: Visualizing an olfactory sensory map. Cell 1996, 87:675-686.
-
(1996)
Cell
, vol.87
, pp. 675-686
-
-
Mombaerts, P.1
Wang, F.2
Dulac, C.3
Chao, S.K.4
Nemes, A.5
Mendelsohn, M.6
Edmondson, J.7
Axel, R.8
-
31
-
-
0030960813
-
Selectivity and response characteristics of human olfactory neurons
-
Rawson NE, Gomez G, Cowart B, Brand JG, Lowry LD, Pribitkin EA, Restrepo D: Selectivity and response characteristics of human olfactory neurons. J Neurophys 1997, 77:1606-1613.
-
(1997)
J Neurophys
, vol.77
, pp. 1606-1613
-
-
Rawson, N.E.1
Gomez, G.2
Cowart, B.3
Brand, J.G.4
Lowry, L.D.5
Pribitkin, E.A.6
Restrepo, D.7
-
32
-
-
0032862870
-
Primate evolution of an olfactory receptor cluster: Diversification by gene conversion and recent emergence of pseudogenes
-
in press
-
Sharon D, Glusman G, Pilpel Y, Khen M, Gruetzner F, Haaf T, Lancet D: Primate evolution of an olfactory receptor cluster: Diversification by gene conversion and recent emergence of pseudogenes. Genomics 1999, in press. First detailed comparative characterization of an OR cluster in humans and chimpanzees.
-
(1999)
Genomics
-
-
Sharon, D.1
Glusman, G.2
Pilpel, Y.3
Khen, M.4
Gruetzner, F.5
Haaf, T.6
Lancet, D.7
-
33
-
-
0032498150
-
Functional expression of a mammalian odorant receptor
-
Zhao H, Ivic L, Otaki JM, Hashimoto M, Mikoshiba K, Firestein S: Functional expression of a mammalian odorant receptor. Science 1998, 279:237-242. Adenovirally-mediated gene transfer was here used to ectopically express the rat OR l7 in a large fraction of rat OSNs. Transepithelial potentials over broad areas of the infected epithelium were measured as a readout for receptor activation. A restricted set of short-chain aliphatic aldehydes were found to stimulate the infected cells, particularly octyl aldehyde. This paper is the first demonstration that the OR genes, isolated in 1991 by Buck and Axel [4], indeed encode receptors for odorants.
-
(1998)
Science
, vol.279
, pp. 237-242
-
-
Zhao, H.1
Ivic, L.2
Otaki, J.M.3
Hashimoto, M.4
Mikoshiba, K.5
Firestein, S.6
-
34
-
-
0032417641
-
Identification of ligands for olfactory receptors by functional expression of a receptor library
-
Krautwurst D, Yau KW, Reed RR: Identification of ligands for olfactory receptors by functional expression of a receptor library. Cell 1998, 95:917-926. Calcium imaging in fura-2 loaded HEK-293 cells was used as an assay for OR activation. The authors describe the first heterologous expression system for vertebrate ORs. The data obtained in [33••] are confirmed and extended in this report.
-
(1998)
Cell
, vol.95
, pp. 917-926
-
-
Krautwurst, D.1
Yau, K.W.2
Reed, R.R.3
-
35
-
-
0031081677
-
Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species
-
Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M: Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. Genomics 1997, 39:239-246.
-
(1997)
Genomics
, vol.39
, pp. 239-246
-
-
Vanderhaeghen, P.1
Schurmans, S.2
Vassart, G.3
Parmentier, M.4
-
36
-
-
0031577447
-
Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: Evidence for their wide distribution in the human genome
-
Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M: Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: Evidence for their wide distribution in the human genome. Biochem Biophys Res Comm 1997, 237:283-287.
-
(1997)
Biochem Biophys Res Comm
, vol.237
, pp. 283-287
-
-
Vanderhaeghen, P.1
Schurmans, S.2
Vassart, G.3
Parmentier, M.4
-
37
-
-
0025763426
-
Avian B-cell development: Generation of an immunoglobulin repertoire by gene conversion
-
McCormack WT, Tjoelker, LW, Thompson CB: Avian B-cell development: Generation of an immunoglobulin repertoire by gene conversion. Annu Rev Immunol 1991, 9:219-241.
-
(1991)
Annu Rev Immunol
, vol.9
, pp. 219-241
-
-
McCormack, W.T.1
Tjoelker, L.W.2
Thompson, C.B.3
|