HLA genes and haplotypes in Ryukyuans suggest recent gene flow to the Okinawa islands

Human Biology

Volumn 71, Issue 3, 1999, Pages 353-365

  Hatta, Yoko ^a   Ohashi, Jun ^a   Imanishi, Tadashi ^b   Kamiyama, Haruo ^c   Iha, Masaharu ^c   Simabukuro, Tsuyoshi ^c   Ogawa, Atsuko ^d   Tanaka, Hidenori ^d   Akaza, Tatsuya ^d   Gojobori, Takashi ^b   Juji, Takeo ^d   Tokunaga, Katsushi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL INSTITUTE OF GENETICS   (Japan)

^c Japanese Red Cross Society   (Japan)

^d JAPANESE RED CROSS MEDICAL CENTER   (Japan)

Author keywords

Gene flow; Haplotype; HLA; Japanese; Okinawa

Indexed keywords

GENE FLOW; GENETIC POLYMORPHISM; HAPLOTYPE; HLA GENE; POLYMERASE CHAIN REACTION; PRINCIPAL COMPONENT ANALYSIS; SEROTYPING;

EID: 0033152069     PISSN: 00187143     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Akaza, T., T. Imanishi, K. Fujiwara et al. 1994. HLA alleles and haplotypes of Japanese population. MHC 1:219-226.
2. Bannai, M., K. Tokunaga, L. Lin et al. 1994. Discrimination of human HLA-DRB1 alleles by PCR-SSCP (single-strand conformation polymorphism) method. Eur. J. Immunogenet. 21:1-9.
3. Bannai, M., K. Tokunaga, T. Imanishi et al. 1996. HLA class II alleles in Ainu living in Hidaka district, Hokkaido, northern Japan. Am. J. Phys. Anthropol. 101:1-9.
4. Chandanayingyong, D., H.A.F. Stephens, R. Klaythong et al. 1997. HLA-A, -B. -DRB1, -DQA1, and -DQB1 polymorphism in Thais. Hum. Immunol. 53:174-182.
5. Chimge, N., K. Kashiwase, H. Tanaka et al. 1996. The HLA system in the population of Mongolia. Tissue Antigens 49:477-483.
6. Dodo, Y., and H. Ishida. 1990. Population history of Japan as viewed from cranial nonmetric variation. J. Anthropol. Soc. Nippon 98:269-287.
7. Dodo, Y., N. Doi, and O. Kondo. 1998. Ainu and Ryukyuan cranial nonmetric variation: Evidence which disputes the Ainu-Ryukyu common origin theory. Anthropol. Sci. 106:99-120.
8. Dodo, Y., O. Kondo, and N. Doi et al. 1997. Amami-Okinawans as viewed from cranial nonmetric traits. Anthropol. Sci. 105:79.
9. Hanihara, K. 1991. Dual structure model for the population history of the Japanese. Jpn. Rev. 2:1-33.
10. Horai, S., K. Murayama, K. Hayasaka et al. 1996. mtDNA polymorphism in East Asian populations, with special reference to the peopling of Japan. Am. J. Hum. Genet. 59:579-590.
11. Imanishi, T., T. Akaza, A. Kimura et al. 1992a. Allele and haplotype frequencies for HLA and complement loci in various ethnic groups. In HLA 1991, K. Tsuji, M. Aizawa, and T. Sasazuki, eds. Oxford, England: Oxford University Press, v. 1, 1065-1220.
12. Imanishi, T., T. Akaza, A. Kimura et al. 1992b. Estimation of allele and haplotype frequencies for HLA and complement loci. In HLA 1991, K. Tsuji, M. Aizawa, and T. Sasazuki, eds. Oxford, England: Oxford University Press, v. 1, 76-79.
13. Kawai, S., S. Maekawajiri, K. Tokunaga et al. 1994. A simple method of HLA-DRB typing using enzymatically amplified DNA and immobilized probes on microtiter plate. Hum. Immunol. 41:121-126.
14. Kawai, S., S. Maekawajiri, K. Tokunaga et al. 1996. Routine low and high resolution typing of the HLA-DRB gene using the PCR-MPH (microtitre plate hybridization) method. Eur. J. Immunogenet. 23:471-486.
15. Nei, M. 1995. The origins of human populations: Genetic, linguistic, and archeological data. In The Origin and Past of Modern Humans as Viewed from DNA, S. Brenner and K. Hanihara, eds. Singapore: World Scientific, 71-91.
16. Nei, M., F. Tajima, and Y. Tateno. 1983. Accuracy of estimated phylogenetic trees from molecular data. II. Gene frequency data. J. Molec. Evol. 19:153-170.
17. Omoto, K. 1992. Some aspects of the genetic composition of the Japanese. In Japanese As a Member of the Asian and Pacific Populations: International Symposium 4, K. Hanihara, ed. Kyoto, Japan: International Research Center for Japanese Studies, 139-145.
18. Omoto, K., and N. Saitou. 1997. Genetic origins of the Japanese: A partial support for the dual structure hypothesis. Am. J. Phys. Anthropol. 102:437-446.
19. Park, M.H., Y.-S. Hwang, K.S. Park et al. 1998. HLA haplotypes in Koreans based on 107 families. Tissue Antigens 51:347-355.
20. Saitou, N., and M. Nei. 1987. The neighbor-joining method: A new method for constructing phylogenetic trees. Molec. Biol. Evol. 4:406-425.
21. Serjeantson, S.W. 1989. HLA genes and antigens. In The Colonization of the Pacific, A.V.S. Hill and S.W. Serjeantson, eds. Oxford, England: Oxford University Press, 120-173.
22. Suzuki, H. 1969. Microevolutionary changes in the Japanese population from the prehistoric age to the present day. J. Fac. Sci. Univ. Tokyo, sec. V, 3:279-308.
23. Tanaka, H., K. Kashiwase, Y. Ishikawa et al. 1997. Distribution of HLA-B-DRB1 haplotypes in five ethnic groups in northeast Asia. In Genetic Diversity of HLA: Functional and Medical Implications, D. Charron, ed. Paris, France: EDK, v. 1, 285-291.
24. Tokunaga, K., T. Imanishi, K. Takahashi et al. 1996. On the origin and dispersal of East Asian populations as viewed from HLA haplotypes. In Prehistoric Mongoloid Dispersals, T. Akazawa and E.J.E. Szathmary, eds. Oxford, England: Oxford University Press, 187-197.
25. Tokunaga, K., H. Tanaka, G. Mauff et al. 1992. Complement studies of the Eleventh International Histocompatibility Workshop. In HLA 1991, K. Tsuji, M. Aizawa, and T. Sasazuki, eds. Oxford, England: Oxford University Press, v. 1, 947-954.
26. Tokunaga, K., E.W. Sideltseva, H. Tanaka et al. 1995. Distribution of HLA antigens and haplotypes in the Buryat population of Siberia. Tissue Antigens 45:98-102.
27. Yamaguchi, B. 1982. A review of the osteological characteristics of the Jomon population in prehistoric Japan. J. Anthropol. Soc. Nippon 90(suppl.):77-90.