Processing, targeting, and antifungal activity of stinging nettle agglutinin in transgenic tobacco

Plant Physiology

Volumn 120, Issue 2, 1999, Pages 421-431

  Does, Mirjam P ^a   Houterman, Petra M ^a   Dekker, Henk L ^b   Cornelissen, Ben J C ^a  

^a Psychiatrisch Centrum Amsterdam   (Netherlands)

^b Medisch Centrum te Amsterdam   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; AGGLUTININ; ANTIFUNGAL ACTIVITY; CARBOXY TERMINAL SEQUENCE; CELL VACUOLE; FUNGAL GROWTH; FUNGAL SPORE; GENE TARGETING; GROWTH INHIBITION; LECTIN; MUTANT; PROTEIN LOCALIZATION; PROTEIN TARGETING; TRANSGENIC PLANT;

BOTRYOTINIA FUCKELIANA; BOTRYTIS; BOTRYTIS CINEREA; COLLETOTRICHUM LINDEMUTHIANUM; FUNGI; NICOTIANA OBTUSIFOLIA; NICOTIANA TABACUM; TABACUM; TRICHODERMA VIRIDE; URTICA DIOICA;

EID: 0033150357     PISSN: 00320889     EISSN: None     Source Type: Journal    
DOI: 10.1104/pp.120.2.421     Document Type: Article

References (79)

1. Altenbach SB, Pearson KW, Meeker G, Staraci LC, Sun SSM (1989) Enhancement of the methionine content of seed proteins by the expression of a chimeric gene encoding a methionine-rich protein in transgenic plants. Plant Mol Biol 13: 513-522
2. Archer BL (1960) The proteins of Hevea brasiliensis latex: isolation and characterization of crystalline hevein. Biochem J 75: 236-240
3. Bäumlein H, Müller A, Schiemann J, Helbing D, Manteuffel R, Wobus U (1987) A legumin B gene of Vicia faba is expressed in developing seeds of transgenic tobacco. Biol Zentbl 106: 569-575
4. Beachy RN, Chen ZL, Bray E, Lawton M, Komeda Y, Nakamura I, Naito S, Anderson E, Dube P, Rogers SG, and others (1986) Expression of subunits of beta-conglycinin in transgenic tobacco and petunia plants. In L Shannon, M Chrispeels, eds, Molecular Biology of Seed Storage Proteins and Lectins. American Society of Plant Physiologists, Rockville, MD, pp 193-201
5. Bednarek SY, Raikhel NV (1991) The barley lectin carboxylterminal propeptide is a vacuolar protein sorting determinant in plants. Plant Cell 3: 1195-1206
6. Bednarek SY, Wilkins TA, Dombrowski JE, Raikhel NV (1990) A carboxyl-terminal propeptide is necessary for proper sorting of barley lectin to vacuoles of tobacco. Plant Cell 2: 1145-1155
7. Beintema JJ (1994) Structural features of plant chitinases and chitin-binding proteins. FEBS Lett 350: 159-163
8. Beintema JJ, Peumans WJ (1992) The primary structure of stinging nettle (Urtica dioica) agglutinin: a two-domain member of the hevein family. FEBS Lett 299: 131-134
9. Blobel G (1980) Intracellular protein topogenesis. Proc Natl Acad Sci USA 77: 1496-1500
10. Broekaert W, Lee H-I, Kush A, Chua N-H, Raikhel N (1990) Wound-induced accumulation of mRNA containing a hevein sequence in laticifers of rubber tree (Hevea brasiliensis). Proc Natl Acad Sci USA 87: 7633-7637
11. Broekaert WF, Van Parijs J, Leyns F, Joos H, Peumans WJ (1989) A chitin-binding lectin from stinging nettle rhizomes with antifungal properties. Science 245: 1100-1102
12. Chapot MP, Peumans WJ, Strosberg AD (1986) Extensive homologies between lectins from non-leguminous plants. FEBS Lett 195: 231-234
13. Chrispeels MJ, Raikhel NV (1992) Short peptide domains target proteins to plant vacuoles. Cell 68: 613-616
14. De Clercq A, Vandewiele M, De Rycke R, Van Damme J, Van Montagu M, Krebbers E, Vandekerckhove J (1990) Expression and processing of an Arabidopsis 2S albumin in transgenic tobacco. Plant Physiol 92: 899-907
15. De Wit PJGM, Spikman G (1982) Evidence for the occurrence of race and cultivar-specific elicitors of necrosis in intercellular fluids of compatible interactions of Cladosporium fulvum and tomato. Physiol Plant Pathol 21: 1-11
16. Does MP, Ng DK, Dekker HL, Peumans WJ, Houterman PM, Van Damme EJM, Cornelissen BJC (1999) Characterization of Urtica dioica agglutinin isolectins and the encoding gene family. Plant Mol Biol 39: 335-347
17. Dombrowski JE, Gomez L, Chrispeels MJ, Raikhel NV (1994) Targeting of proteins to the vacuole. In S Gelvin, R Schilperoort, eds, Plant Molecular Biology Manual, Ed 2. Kluwer Academic Publishers, Dordrecht, The Netherlands, pp 1-29
18. Dombrowski JE, Schroeder MR, Bednarek SY, Raikhel NV (1993) Determination of the functional elements within the vacuolar targeting signal of barley lectin. Plant Cell 5: 587-596
19. Dorel C, Voelker TA, Herman EM, Chrispeels MJ (1989) Transport of proteins to the plant vacuole is not by bulk flow through the secretory system, and requires positive sorting information. J Cell Biol 108: 327-337
20. Gomord V, Faye L (1996) Signals and mechanisms involved in intracellular transport of secreted proteins in plants. Plant Physiol Biochem 34: 165-181
21. Greenwood JS, Chrispeels MJ (1985) Correct targeting of the bean storage protein phaseolin in the seeds of transformed tobacco. Plant Physiol 79: 65-71
22. Harris N, Henderson SJ, Abbot J, Mulcrone J, Davies JT (1993) Seed development and structure. Proc Phytochem Soc Eur 35: 3-21
23. Hattori T, Nakagawa T, Maeshima M, Nakamura K, Asahi T (1985) Molecular cloning and nucleotide sequence of cDNA for sporamin, the major soluble protein of sweet potato tuberous roots. Plant Mol Biol 5: 313-320
24. Hiraiwa N, Kondo M, Nishimura M, Hara-Nishimura I (1997) An aspartic endopeptidase is involved in the breakdown of propeptides of storage proteins in protein-storage vacuoles of plants. Eur J Biochem 246: 133-141
25. Holwerda BC, Padgett HS, Rogers JC (1992) Proaleurain vacuolar targeting is mediated by short contiguous peptide interactions. Plant Cell 4: 307-318
26. Hood EE, Gelvin SB, Melhers LS, Hoekema A (1993) New Agrobacterium helper plasmids for gene transfer to plants. Transgenic Res 2: 208-218
27. Horsch RB, Fry JE, Hofmann NL, Eichholtz D, Rogers SG, Fraley RT (1985) A simple and general method for transferring genes into plants. Science 227: 1229-1231
28. Jongedijk E, Tigelaar H, Van Roekel JSC, Bres-Vloemans SA, Dekker I, Van den Elzen PJM, Cornelissen BJC, Melchers LS (1995) Synergistic activity of chitinases and β-1,3-glucanases enhances fungal resistance in transgenic tomato plants. Euphytica 85: 173-180
29. Lee H-I, Broekaert WF, Raikhel NV (1991) Co-and posttranslational processing of the hevein preproprotein of latex of the rubber tree (Hevea brasiliensis). J Biol Chem 266: 15944-15948
30. Lerner DR, Raikhel NV (1989) Cloning and characterization of root-specific barley lectin. Plant Physiol 91: 124-129
31. Lerner DR, Raikhel NV (1992) The gene for stinging nettle lectin (Urtica dioica agglutinin) encodes both a lectin and a chitinase. J Biol Chem 267: 11085-11091
32. Linthorst HJM, Danhash N, Brederode FT, Van Kan JAL, De Wit PJGM, Bol JF (1991) Tobacco and tomato PR proteins homologous to win and pro-hevein lack the "hevein" domain. Mol Plant-Microbe Interact 4: 586-592
33. Mansfield MA, Peumans WJ, Raikhel NV (1988) Wheat-germ agglutinin is synthesized as a glycosylated precursor. Planta 173: 482-489
34. Matsuoka K, Matsumoto S, Hattori T, Machida Y, Nakamura K (1990) Vacuolar targeting and posttranslational processing of the precursor to the sweet potato tuberous root storage protein in heterologous plant cells. J Biol Chem 265: 19750-19757
35. Mauch F, Mauch-Mani B, Boller T (1988) Antifungal hydrolases in pea tissue. Plant Physiol 88: 936-942
36. Mauch F, Staehelin, LA (1989) Functional implications of the subcellular localization of ethylene-induced chitinase and β-1,3-glucanase in bean leaves. Plant Cell 1: 447-457
37. Melchers LS, Sela-Buurlage MB, Vloemans SA, Woloshuk CP, Van Roekel JSC, Pen J, Van den Elzen PJM, Cornelissen BJC (1993) Extracellular targeting of the vacuolar tobacco proteins AP24, chitinase and β-1,3-glucanase in transgenic plants. Plant Mol Biol 21: 583-593
38. Mishkind ML, Palevitz BA, Raikhel NV, Keegstra K (1983) Localization of wheat germ agglutinin-like lectins in various species of the Gramineae. Science 220: 1290-1292
39. Müntz K (1998) Deposition of storage proteins. Plant Mol Biol 38: 77-99
40. Nakamura K, Matsuoka K (1993) Protein targeting to the vacuole in plant cells. Plant Physiol 101: 1-5
41. Neuhaus J-M (1996) Protein targeting to the plant vacuole. Plant Physiol Biochem 34: 217-221
42. Neuhaus J-M, Fritig B, Linthorst HJM, Meins F, Mikkelsen JD, Ryals J (1996) A revised nomenclature for chitinase genes. Plant Mol Biol Rep 14: 102-104
43. Neuhaus J-M, Rogers JC (1998) Sorting of proteins to vacuoles in plant cells. Plant Mol Biol 38: 127-144
44. Neuhaus J-M, Sticher L, Meins F, Boiler T (1991) A short C-terminal sequence is necessary and sufficient for the targeting of chitinases to the plant vacuole. Proc Natl Acad Sci USA 88: 10362-10366
45. Paul W, Amiss J, Try R, Praekelt U, Scott R, Smith H (1995) Correct processing of the kiwifruit protease actinidin in transgenic tobacco requires the presence of the C-terminal propeptide. Plant Physiol 108: 261-268
46. Pen J, Molendijk L, Quax WJ, Sijmons PC, Van Ooyen AJJ, Van den Elzen PJM, Rietveld K, Hoekema A (1992) Production of active Bacillus licheniformis alpha-amylase in tobacco and its application in starch liquefaction. Bio/Technology 10: 292-296
47. Peumans WJ, De Ley M, Broekaert WF (1984) An unusual lectin from stinging nettle (Urtica dioica) rhizomes. FEBS Lett 177: 99-103
48. Praekelt UM, McKee A, Smith H (1988) Molecular analysis of actinidin, the cysteine protease of Actinidia chinensis. Plant Mol Biol 10: 193-202
49. Racusen D, Foote M (1980) A major soluble glycoprotein of potato tubers. J Food Biochem 4: 43-52
50. Raikhel NV, Lerner DR (1991) Expression and regulation of lectin genes in cereals and rice. Dev Genet 12: 255-260
51. Robinson DG, Hinz G, Holstein SEH (1998) The molecular characterization of transport vesicles. Plant Mol Biol 38: 49-76
52. Rodrigo I, Vera P, Van Loon LC, Conejero V (1991) Degradation of tobacco pathogenesis-related proteins. Plant Physiol 95: 616-622
53. Runeberg-Roos P, Kervinen J, Kovaleva V, Raikhel NV, Gal S (1994) The aspartic proteinase of barley is a vacuolar enzyme that processes probarley lectin in vitro. Plant Physiol 105: 321-329
54. Saalbach G, Jung R, Kunze G, Saalbach I, Adler K, Müntz K (1991) Different legumin protein domains act as vacuolar targeting signals. Plant Cell 3: 695-708
55. Saalbach G, Rosso M, Schumann U (1996) The vacuolar targeting signal of the 2S albumin from brazil nut resides at the C terminus and involves the C-terminal propeptide as an essential element. Plant Physiol 112: 975-985
56. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular Cloning: A Laboratory Manual, Ed 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
57. Sanger F, Nicklen S, Coulson AR (1977) DNA sequencing with chain-termination inhibitors. Proc Natl Acad Sci USA 74: 5463-5467
58. Schägger H, Von Jagow G (1987) Tricine-sodium dodecyl sulfatepolyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem 166: 368-379
59. Schlumbaum A, Mauch F, Vögeli V, Boller T (1986) Plant chitinases are potent inhibitors of fungal growth. Nature 324: 365-367
60. Sela-Buurlage MB (1996) In vitro sensitivity and tolerance of Fusarium solani towards chitinases and β-1,3-glucanases. PhD thesis. Landbouwuniversiteit Wageningen, Wageningen, The Netherlands
61. Sela-Buurlage MB, Ponstein AS, Bres-Vloemans SA, Melchers LS, Van den Elzen PJM, Cornelissen BJC (1993) Only specific tobacco (Nicotiana tabacum) chitinases and β-1,3-glucanases exhibit antifungal activity. Plant Physiol 101: 857-863
62. Shinshi H, Neuhaus J-M, Ryals J, Meins F (1990) Structure of a tobacco endochitinase gene: evidence that different chitinase genes can arise by transposition of sequences encoding a cysteine-rich domain. Plant Mol Biol 14: 357-368
63. Shinshi H, Wenzler H, Neuhaus J-M, Felix G, Hofsteenge J, Meins F (1988) Evidence for N-and C-terminal processing of a plant defense-related enzyme: primary structure of tobacco prepro-β-1,3-glucanase. Proc Natl Acad Sci USA 85: 5541-5545
64. Singh NK, Nelson DE, Kuhn D, Hasegawa PM, Bressan RA (1989) Molecular cloning of osmotin and regulation of its expression by ABA and adaptation to low water potential. Plant Physiol 90: 1096-1101
65. Smith JJ, Raikhel NV (1989) Nucleotide sequences of cDNA clones encoding wheat germ agglutinin isolectins A and D. Plant Mol Biol 13: 601-603
66. Soedjanaatmadja UMS, Subroto T, Beintema JJ (1995) Processed products of the hevein precursor in the latex of the rubber tree (Hevea brasiliensis). FEBS Lett 363: 211-213
67. Sonnewald U, Sturm A, Chrispeels MJ, Willmitzer L (1989) Targeting and glycosylation of patatin the major potato tuber protein in leaves of transgenic tobacco. Planta 179: 171-180
68. Sticher L, Hinz U, Meyer AD, Meins F (1992) Intracellular transport and processing of a tobacco vacuolar β-1,3-glucanase. Planta 188: 559-565
69. Stinissen HM, Peumans WJ, Chrispeels MJ (1984) Subcellular site of lectin synthesis in developing rice embryos. EMBO J 3: 1979-1985
70. Sturm A, Voelker TA, Herman EM, Chrispeels MJ (1988) Correct glycosylation, Golgi-processing, and targeting to protein bodies of the vacuolar protein phytohemagglutinin in transgenic tobacco. Planta 175: 170-183
71. Ten Kate TK, Van Balen R, Smeulders AWM, Groen FCA, Den Boer GA (1990) SCILIAM, a multi-level interactive image processing environment. Pattern Recogn Lett 11: 429-441
72. Van Damme EJM, Broekaert WF, Peumans WJ (1988) The Urtica dioica agglutinin is a complex mixture of isolectins. Plant Physiol 86: 598-601
73. Van Damme EJM, Peumans WJ (1987) lsolectin composition of individual clones of Urtica dioica: evidence for phenotypic differences. Physiol Plant 71: 328-334
74. Van Parijs J, Joosen HM, Peumans WJ, Geuns JM, Van Laere AJ (1992) Effect of the Urtica dioica agglutinin on germination and cell wall formation of Phycomyces blakesleeanus Burgeff. Arch Microbiol 158: 19-25
75. Walujono K, Scholma RA, Beintema JJ, Mariono A, Hahn AM (1975) Amino acid sequence of hevein. In Proceedings of the International Rubber Conference, Vol 2. Rubber Research Institute of Malays, Kuala Lumpur, Malaysia, pp 518-531
76. Wilkins TA, Bednarek SY, Raikhel NV (1990) Role of propeptide glycan in post-translational processing and transport of barley lectin to vacuoles in transgenic tobacco. Plant Cell 2: 301-313
77. Wilkins TA, Raikhel NV (1989) Expression of rice lectin is governed by two temporally and spatially regulated mRNAs in developing embryos. Plant Cell 1: 541-549
78. Woloshuk CP, Meulenhoff EJS, Sela-Buurlage MB, Van den Elzen PJM, Cornelissen BJC (1991) Pathogen-induced proteins with inhibitory activity toward Phytophthora infestans. Plant Cell 3: 619-628
79. Wright HT, Sandrasegaram G, Wright CS (1991) Evolution of a family of N-acetylglucosamine binding proteins containing the disulfide-rich domain of wheat germ agglutinin. J Mol Evol 33: 283-294