Acetylator phenotype prevalence in HIV-infected patients without previous trimethoprim-sulfamethoxazole hypersensitivity

Biomedicine and Pharmacotherapy

Volumn 53, Issue 5-6, 1999, Pages 286-287

  Quirino, T ^a   Bonfanti, P ^a   Arcidiacono, M ^b   Pusterla, L ^c   Cagni, A ^d   Scaglione, F ^b   Milazzo, F ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c Sant'Anna Como Hospital   (Italy)

^d Department of Pediatrics   (Italy)

Author keywords

Acetylator phenotype; Drug hypersensitivity; HIV; Sulfa drugs

Indexed keywords

COTRIMOXAZOLE; CYTOCHROME P450;

ADULT; AIDS RELATED COMPLEX; ARTICLE; DRUG ACETYLATION; DRUG HYPERSENSITIVITY; FEMALE; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PNEUMOCYSTIS PNEUMONIA; PRIORITY JOURNAL;

EID: 0033150089     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0753-3322(99)80101-2     Document Type: Letter

References (9)

1. Carr A, Swason C, Penny R, Cooper DA. Clinical and laboratory markers of hypersensibility to trimethoprim-sulfamethoxazole in patients with Pneumocystis carinii pneumonia and AIDS. J Infect Dis 1993 ; 167 : 180-5.
2. Van der Ven AJ, Koopamns PP, Vree TB, Van der Men JW. Adverse reactions to cotrimoxazole in HIV infection. Lancet 1991 ; 338 : 431-3.
3. Koopmans PP, Van der Ven AJ, Vree TB, Van der Men JWM. Pathogenesis of hypersensitivity reactions to drugs in patients with HIV infection - Allergic or toxic? AIDS 1995 ; 9 : 217-22.
4. Mathelier-Fusade P, Leynadier F. Intollerance aux sulfamides chez les sujets infectes per le FHV. Press Med 1993 ; 22 : 1363-5.
5. Lee BI, Delahunty T, Safrin F. The hydroxilamine of sulfamethoxazole and adverse reactions in patients with acquired immunodeficiency syndrome. Clin Pharmacol Ther 1994 ; 56 : 184-90.
6. Van der Ven AI, Koopmans PP, Vree TB, Van der Meen JW. Adverse reactions to cotrimoxazole in HIV infection. Lancet 1991 ; 338 : 431-3.
7. Carr A, Gross AS, Hoskins JM, Penny R, Cooper DA. Acetylation phenotype and coetaneous hypersensitivity to trimethoprim-sulfamethoxazole in HIV-infected patients. AIDS 1994 ; 8 : 333-7.
8. Lee BL, Wong D, Benowits NL, Sullam PM. Altered patterns of drug metabolism in patients with acquired immunod-eficiency syndrome. Clin Pharmacol Ther 1993 ; 53 : 529-35.
9. Olson W, Miceli J, Weber W. Dose-dependent changes in sulphametazine kinetics in rapid and slow isoniazid acetylators. Clin Pharmacol Ther 1978 ; 23 : 204-11.