Attenuation of brain hyperbaric oxygen toxicity by fasting is not related to ketosis

Undersea and Hyperbaric Medicine

Volumn 26, Issue 2, 1999, Pages 99-103

  Chavko, M ^a   Braisted, J C ^a   Harabin, A L ^a,b  

^a NAVAL MEDICAL RESEARCH CENTER   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Brain; Central nervous system oxygen toxicity; Convulsions; Glucose; Ketosis; Starvation

Indexed keywords

1,3 BUTANEDIOL; 1,3-BUTYLENE GLYCOL; 3 HYDROXYBUTYRIC ACID; BIOLOGICAL MARKER; BUTANEDIOL; KETONE BODY;

ANIMAL; ARTICLE; BLOOD; DIET RESTRICTION; ELECTROENCEPHALOGRAPHY; GERMFREE ANIMAL; GLUCOSE BLOOD LEVEL; HYPERBARIC OXYGEN; HYPOGLYCEMIA; KETOACIDOSIS; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PRESSURE; RAT; SEIZURE; SPRAGUE DAWLEY RAT;

3-HYDROXYBUTYRIC ACID; ANIMALS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; BUTYLENE GLYCOLS; ELECTROENCEPHALOGRAPHY; FASTING; HYPERBARIC OXYGENATION; HYPOGLYCEMIA; KETONE BODIES; KETOSIS; MALE; PARTIAL PRESSURE; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 0033143687     PISSN: 10662936     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Melamed Y, Shupak A, Bitterman H. Medical problems associated with underwater diving. N Engl J Med 1992; 26:30-35.
2. Tibbies PM, Edelsberg JS. Hyperbaric-oxygen therapy. N Engl J Med 1996; 34:1642-1648.
3. Lambertsen CJ. Effects of oxygen at high partial pressure. In: Fenn WO, Rahn H, eds. Handbook of physiology: respiration, vol II. Washington, DC: American Physiological Society, 1965:1027-1046.
4. Peterman MG. Epilepsy in childhood. JAMA 1948; 138:1012-1018.
5. DeVivo DC, Malas KL, Lackie MP. Starvation and seizures. Observations on the electroconvulsive threshold and cerebral metabolism of the starved adult rat. Arch Neurol 1975; 32: 755-760.
6. Mahoney AW, Hendricks DG, Bernhard N, Sisson DV. Fasting and ketogenic diet effects on audiogenic seizure susceptibility of magnesium deficient rats. Pharmacol Biochem Behav 1983; 18: 683-687.
7. Millichap JG, Jones JD, Rudis BR. Mechanism of anticonvulsant action of ketogenic diet. Am J Dis Child 1964; 107:593-604.
8. Uhlemann ER, Neims AH. Anticonvulsant properties of the ketogenic diet in mice. J Pharmacol Exp Ther 1972; 80:231-238.
9. Appleton DB, DeVivo DC. An animal model for the ketogenic diet. Electroconvulsive threshold and biochemical alterations consequent upon a high-fat diet. Epilepsia 1974; 15:211-227.
10. Prasad AN, Stafstrom CF, Holmes GL. Alternative epilepsy therapies: the ketogenic diet, immunoglobulins, and steroids. Epilepsia 1996; 37(suppl 1):S81-S95.
11. Campbell JA. Oxygen poisoning and tumor growth. Br J Exp Pathol 1937; 18:191-197.
12. Bitterman N, Skapa E, Gutterman A. Starvation and dehydration attenuates CNS oxygen toxicity in rats. Brain Res 1997; 761:146-150.
13. Carroll JJ, Smith N, Babson AL. A calorimetric serum glucose determination using hexokinase and glucose-6-phosphate dehydrogenase. Biochem Med 1970; 4:171-176.
14. Williamson DH, Mellanby J, Krebs HLA. Enzymic determination of D(-)-β-hydroxybutyric acid and acetoacetic acid in blood. Biochem J 1962; 82:90-95.
15. Tate RL, Mehlman MA, Tobin RB. Metabolic fate of 1,3-butanediol in the rat: conversion to β-hydroxybutyrate. J Nutr 1971; 101:1719-1726.
16. Kirsch JR, D'Alecy LG, Mongroo PB. Butanediol induced ketosis increases tolerance to hypoxia in the mouse. Stroke 1980; 11: 506-513.
17. Marie C, Bralet A-M, Bralet J. Protective action of 1,3-butanediol in cerebral ischemia. A neurologic, histologic, and metabolic study. J Cereb Blood Flow Metab 1987; 7:794-800.
18. Lundgren J, Smith M-J, Mans AM, Siesjo BK. Ischemic brain damage is not ameliorated by 1,3-butanediol in hyperglycemic rats. Stroke 1992; 23:719-724.
19. Huttlenlocher PR. Ketonemia and seizures: metabolic and anticonvulsant effects of two ketogenic diets in childhood epilepsy. Pediatr Res 1976; 10:536-540.
20. Torbati D, Greenberg J, Lambertsen CJ. Correlation of brain glucose utilization and cortical electrical activity during development of brain oxygen toxicity. Brain Res 1983; 262:267-273.
21. Beckman DL, Crittenden DJ, Overton DH, Blumenthal SJ. Influence of blood glucose on convulsive seizures from hyperbaric oxygen. Life Sci 1982; 31:45-49.
22. Habib MP, Dickerson F, Moradian AD. Ethane production rate in vivo is reduced with dietary restriction. J Appl Physiol 1990; 68:2588-2590.
23. Ueta Y, Levy A, Chowdrey HS, Lightman SL. Inhibition of hypothalamic nitric oxide synthase gene expression in the rat paraventricular nucleus by food deprivation is independent of serotonin depletion. J Neuroendocrinol 1995; 7:861-865.
24. Zhang J, Su Y, Oury TD, Piantadosi CA. Cerebral amino acids, norepinephrine and nitric oxide metabolism in CNS oxygen toxicity. Brain Res 1993; 606:56-62.
25. Chavko M, Braisted JC, Outsa NJ, Harabin AL. Role of cerebral blood flow in seizures from hyperbaric oxygen exposure. Brain Res 1998; 791:75-82.
26. Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990; 87:1620-1624.
27. Jung RT, Sherry PS, James WPT. Nutritional effects on thyroid arid catecholamine metabolism. Clin Sci 1980; 58:183-191.
28. Cross MH, Houlihan RT. Sympathoadrenomedullary response of the rat to high oxygen pressures. J. Appl Physiol 1969; 27:523-527.
29. Torbati D, Torbati A. Blood glucose as a predictive measure for central nervous system oxygen toxicity in conscious rats. Undersea Biomed Res 1986; 13:147-154.
30. Singh AK, Bannister FW, Effect of adrenalectomy on convulsions induced by high-pressure oxygen. Can J Physiol Pharmacol 1979; 57:688-694.
31. Torbati D. Effect of propranolol on brain electrical activity during hyperbaric oxygenation in the rat. Undersea Biomed Res 1985; 12:423-429.
32. Wronska D, Niezgoda J, Sechman A, Bobek S. Food deprivation suppresses stress-induced rise in catabolic hormones with a concomitant tendency to potentiate the increment of blood glucose. Physiol Behav 1990; 48:531-537.