Functional characterization of α1-adrenergic receptors in experimental vein grafts

Journal of Surgical Research

Volumn 84, Issue 1, 1999, Pages 40-45

  Davies, Mark G ^a   Huynh, Tam T T ^a   Hagen, Per Otto ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Function; Intimal hyperplasia; Rabbit; Smooth muscle cells; Vein grafts; 1 adrenoceptor

Indexed keywords

2 [[2 (2,6 DIMETHOXYPHENOXY)ETHYL]AMINOMETHYL] 1,4 BENZODIOXAN; 5 METHYLURAPIDIL; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; CHLOROETHYLCLONIDINE; GUANINE NUCLEOTIDE BINDING PROTEIN; PERTUSSIS TOXIN; PHENYLEPHRINE; PRAZOSIN; 5-METHYLURAPIDIL; ALPHA ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; BORDETELLA VIRULENCE FACTOR; DIOXANE DERIVATIVE; PIPERAZINE DERIVATIVE;

ALPHA ADRENERGIC STIMULATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY TONE; ARTICLE; COMMON CAROTID ARTERY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; JUGULAR VEIN; MALE; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; RABBIT; SIGNAL TRANSDUCTION; VEIN GRAFT; VEIN TONE; ANIMAL; CAROTID ARTERY; DRUG ANTAGONISM; DRUG EFFECT; OSMOLARITY; PATHOPHYSIOLOGY; PHYSIOLOGY; TRANSPLANTATION; VASOCONSTRICTION;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; CAROTID ARTERIES; CAROTID ARTERY, COMMON; DIOXANES; GTP-BINDING PROTEINS; JUGULAR VEINS; MALE; OSMOLAR CONCENTRATION; PERTUSSIS TOXIN; PHENYLEPHRINE; PIPERAZINES; PRAZOSIN; RABBITS; RECEPTORS, ADRENERGIC, ALPHA; VASOCONSTRICTION; VIRULENCE FACTORS, BORDETELLA;

EID: 0033137353     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1999.5600     Document Type: Article

References (25)

1. Davies M. G., Hagen P.-O. Pathophysiology of vein graft failure. Eur. J. Vasc. Endovasc. Surg. 9:1995;7.
2. Davies M. G., Hagen P.-O. Structural and functional consequences of bypass grafting with autologous vein. Cryobiology. 31:1994;63.
3. Makhoul R. G., Davis W. S., Mikat E. M., McCann R. L., Hagen P.-O. Responsiveness of vein grafts to stimulation with norepinephrine and 5 hydroxytryptamine. J. Vasc. Surg. 6:1987;32.
4. Waris T., Loefstedt T., Partanen S., Smitten K. V. Innervation of synergic vein grafts in the rat: The regeneration of adrenergic nerves. J. Surg. Res. 37:1984;472.
5. Soliman A. S., Tackett R. L. Altered responsiveness of saphenous vein grafts to norepinephrine and tyramine: Relation to tissue catecholamine stores. J. Cardiovasc. Pharmacol. 17:1991;154.
6. Soliman A. S., Tackett R. L. Early alterations in vascular reactivity of autogenous saphenous vein grafts. Coronary Artery Dis. 3:1992;523.
7. Mimura Y., Kobayashi S., Notoya K. Activation by alpha-1-adrenergic agonists of the progression phase in the proliferation of primary cultures of smooth muscle cells in mouse and rat aorta. Biol. Pharm. Bull. 18:1995;1373.
8. Noveral J. P., Grunstein M. M. Adrenergic receptor mediated regulation of cultured rabbit airway smooth muscle cell proliferation. Am. J. Physiol. 267:1994;PL291.
9. Li Y., Han C. D. Effects of alpha-1 adrenergic receptor subtype activation of proliferation of SMC in rabbit aorta. Sheng-Li-Hsueh-Pao [Acta Physiol. Sin.]. 47:1995;498.
10. Chen L. Q., Xin X. H., Eckhart A. D., Yang N. Y., Faber J. E. Regulation of vascular smooth muscle growth by alpha (1) adrenoceptor subtypes in vitro and in situ. J. Biol. Chem. 270:1995;30980.
11. Davies M. G., Barber L., Dalen H., Svendsen E., Hagen P.-O. Pharmacologic control of the structural and functional consequences of vein graft intimal hyperplasia by a 21-aminosteroid (U74389G). Eur. J. Vasc. Surg. 8:1994;156.
12. Finney D. J. Quantal responses and the tolerance distribution. Statistical Methods in Biological Assay. 1978;Charles Griffin, London. p. 349-369.
13. Kenakin T. Pharmacologic Analysis of Drug Receptor Interaction. 1993;Raven Press, New York. p. 483.
14. Davies M. G., Dalen H., Svendsen E., Hagen P.-O. The functional and morphological consequences of balloon catheter injury in veins. J. Surg. Res. 55:1994;122.
15. Hu Z. W., Shi X. Y., Lin R. Z., Hoffman B. B. Alpha adrenergic receptors activate phosphatidylinositol-3-kinase in human vascular smooth muscle cells: Role in mitogenesis. J. Biol. Chem. 271:1996;8977.
16. Allen L. F., Lefkowitz R. J., Caron M. G., Cotecchia S. G-protein coupled receptor genes as protooncogenes: Constitutively activating mutation of the alpha1B adrenergic receptor enhances mitogenesis and tumorigenesis. Proc. Natl. Acad. Sci. USA. 88:1991;11354.
17. O'Malley M. K., Hagen P.-O., Mikat E. M., Cole E. W., Radic Z. S., McCann R. L. Contraction and sensitivity to norepinephrine after endothelial denudation is inhibited by prazosin. Surgery. 99:1986;36.
18. Davies M. G., Hagen P.-O. Influence of perioperative storage solutions on long term vein graft function and morphology. Ann. Vasc. Surg. 8:1994;150.
19. Davies M. G., Klyachkin M. L., Massey M. F., Svendsen E., Hagen P.-O. A comparative study of EDRF-mediated relaxation and smooth muscle cell function in arterial and venous vein bypass grafts. Cardiovasc. Surg. 4:1996;150.
20. Davies M. G., Klyachkin M. L., Dalen H., Svendsen E., Hagen P.-O. Regression of intimal hyperplasia with restoration of EDRF-mediated relaxation in experimental vein grafts. Surgery. 114:1993;258.
21. Fann J. L., Sokoloff M. H., Sarris G. E., Yun K. L., Kosek J. C., Millar D. C. The reversibility of canine vein graft arterialization. Circulation. 82:1990;9.
22. 2in vitroin situ. FASEB J. 9:1995;A317.
23. Norman P. E., House A. K. Influence of prazosin on experimental vein graft intimal thickening. Br. J. Surg. 79:1992;276.
24. O'Malley M. K., McDermott E., Mehigan D., Mikat E. M., O'Higgins N. Role for prazosin in reducing the development of rabbit intimal hyperplasia after endothelial denudation. Br. J. Surg. 76:1989;936.
25. Davies M. G., Ramkumar V., Gettys T., Hagen P.-O. The expression and function of G-proteins in experimental vein grafts. J. Clin. Invest. 94:1994;1680.