Pharmacological properties of a novel gastrointestinal prokinetic benzamide selective for human 5-HT4 receptor versus human 5-HT3 receptor

Pharmacological Research

Volumn 39, Issue 5, 1999, Pages 375-382

  Nagakura, Yukinori ^a   Akuzawa, Shinobu ^a   Miyata, Keiji ^a   Kamato, Takeshi ^a   Suzuki, Takeshi ^a   Ito, Hiroyuki ^a   Yamaguchi, Tokio ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Human 5 HT3 receptor; Human 5 HT4 receptor; Intestinal propulsion

Indexed keywords

1 METHYL 3 INDOLECARBOXYLIC ACID [1 [2 (METHYLSULFONYLAMINO)ETHYL] 4 PIPERIDINYLMETHYL] ESTER; 2 CHLORO 5 METHOXY 4 [5 (2 PIPERIDYLMETHYL) 1,2,4 OXADIAZOL 3 YL]ANILINE; BENZAMIDE DERIVATIVE; CISAPRIDE; RENZAPRIDE; SEROTONIN 3 RECEPTOR; SEROTONIN 4 RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SPASMOLYTIC AGENT; UNCLASSIFIED DRUG; ZACOPRIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONSTIPATION; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; ESOPHAGUS; GASTROINTESTINAL DISEASE; INTESTINE CONTRACTION; INTESTINE MOTILITY; INTESTINE TRANSIT TIME; ISOTOPE LABELING; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RADIOASSAY; RAT; SMOOTH MUSCLE CONTRACTION; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0033136357     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1006/phrs.1998.0454     Document Type: Article

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