An in vitro study on the toxic effects of nonylphenols (NP) in mitochondria

Chemosphere

Volumn 38, Issue 9, 1999, Pages 1997-2001

  Bragadin, M ^a   Perni, G ^a   Iero, A ^c   Manente, S ^a   Rizzoli, V ^b   Scutari, G ^b  

^a CA' FOSCARI UNIVERSITY OF VENICE   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIA; NONYLPHENOLS; OXIDATIVE PHOSPHORYLATION; POLYETHOXILATEDALKYLPHENOLS DETERGENTS;

BIODEGRADATION; CELLS; COMPOSITION EFFECTS; DETERGENTS; PHENOLS;

TOXICITY;

ALKYLPHENOL; DETERGENT; NONYLPHENOL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIODEGRADATION; ECOTOXICITY; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; RAT;

ANIMALS; BIODEGRADATION, ENVIRONMENTAL; DETERGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; LIVER; MITOCHONDRIA; PHENOLS; RATS; RATS, WISTAR; UNCOUPLING AGENTS;

ANIMALIA;

EID: 0033136304     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0045-6535(98)00412-3     Document Type: Article

References (11)

1. M. Bragadin and P. Dell'Antone, Mitochondrial Bioenergetics as affected by cationic detergents, Arch. Environ. Contam. Toxicol., 30, 280-284 (1994)
2. M. Bragadin, G. Perin, S. Raccanelli and S. Manente, The accumulation in Lysosomes of the Anionic Detergent Linear Alkylbenzene Sulphonate (LAS) Arch. Environ. Contam. Toxicol. 15, 1749-1751 (1996)
3. G.A. Blondin, L.M. Knabeloch, H.W. Read and J.M. Arkin, Mammalian Mitochondria as "in vitro" monitors of water quality, Bull. Environ. Contam. Toxicol. 38, 467-474 (1987)
4. R.D. Shannon, G.D. Boarman, A.M. Dietrich and D.R. Bevan, Mitochondrial response to chlorophenols as a short-term toxicity assay, Environ. Toxicol. Chem. 10, 57-66 (1991).
5. M. Bragadin and P. Dell'Antone, A new in vitro toxicity test based on the response to toxic substances in solutions of mitochondria from beef heart, Arch. Environ. Contam. Toxicol. 27, 410-414 (1994).
6. B. Fell, Tenside: Aktueller Stand-Absehbare Entwicklungen, Tenside Surf. Det, 28, 385-395 (1991).
7. W. Giger, P.H. Brunner and C. Schaffer, Nonylphenol in Sewage Sludge: Accumulation of Toxic Metabolites from Nonionic Surfactants, Science (Washington D,C.) 225, 623 (1984).
8. W. Giger, M. Ahel, H.U. Coch, C. Laubscher, C. Schaffner and J. Schneider, Behaviour of Alkylphenol Polyethoxylate Surfactants and of Nitrilotriacetate in Sewage Treatement, Water Sci. Technol. 19, 449-460 (1987).
9. M. Ahel, W. Giger and T. Konrad, Persistent Organic Chemicals in Sewage Effluents. Determinations of Nonylphenoxy Carboxylic Acids by high-resolution Gas Chromatography Mass Spectrometry and High performance liquid Chromatography, Environ. Sci. Technol. 21, 697-703 (1987).
10. R.W. Estabrook, Mitochondrial Respiratory control and the Polarographic Measurement of ADP:O Ratios, in Methods in Enzymology Vol X Edited by Ronald W. Estabrook, Maynard E. Pullman Academic Press New York and London p.47 (1967).
11. M. Stockdale and M. Seldwin, Effects of ring substituents on the activity of phenols as inhibitors and uncouplers of mitochondrial respiration, Eur. J. Biochem. 21, 565-574 (1971).