IL-8 degradation by Porphyromonas gingivalis proteases

Microbial Pathogenesis

Volumn 26, Issue 5, 1999, Pages 275-280

  Zhang, J ^a   Dong, H ^a   Kashket, S ^a   Duncan, M J ^a  

^a FORSYTH INSTITUTE   (United States)

Author keywords

Epithelial cells; IL 8; Porphyromonas gingivalis; Proteases

Indexed keywords

CYTOKINE; INTERLEUKIN 8; MESSENGER RNA; PROTEINASE; PROTEINASE INHIBITOR;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEGRADATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MESSENGER RNA SYNTHESIS; NORTHERN BLOTTING; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL;

NEGIBACTERIA; PORPHYROMONAS GINGIVALIS;

EID: 0033135922     PISSN: 08824010     EISSN: None     Source Type: Journal    
DOI: 10.1006/mpat.1998.0277     Document Type: Article

References (20)

1. Lamont RJ, Hsiao GW, Gil S. Identification of a molecule of Porphyromonas gingivalis that binds to Streptococcus gordonii. Micr Pathogen 1994; 17: 355-60.
2. Kamaguchi A, Baba H, Hoshi M, Inomata K. Co-aggregation between Porphyromonas gingivalis and mutans streptococci. Microbiol Immunol 1994; 38: 457-60.
3. Tokuda M, Duncan MJ, Cho M-I, Kuramitsu HK. Role of Porphyromonas gingivalis protease activity in colonization of oral surfaces. Infect Immun 1996; 64: 4067-73.
4. Wienberg A, Belton CM, Park Y, Lamont RJ. Role of fimbriae in Porphyromonas gingivalis invasion of epithelial cells. Infect Immun 1997; 65: 313-16.
5. Kohtani M, Ono H, Shibata H, Okamura Y, TAnaka T, Fujiwara T, Kimura S, Hamada S. Cysteine protease of Porphyromonas gingivalis 381 enhances binding of fimbriae to cultured human fibroblasts and matrix proteins. Infect Immun 1996; 64: 756-62.
6. Lantz MS, Allen RD, Vail TA, Switalski LM, Hook M. Specific cell components of Bacteroides gingivalis mediate binding and degradation of human fibrinogen. J BacTeriol 1991; 173: 495-504.
7. Pavloff N, Potempa J, Pike RN, Prochazka V, Kiefer MC, Travis J, Barr PJ. Molecular cloning and structural characterization of the arg-gingipain proteinase of Porphyromonas gingivalis. J Biol Chem 1994; 270: 1007-10.
8. Okamoto K, Kadowaki T, Nakayama K, Yamamoto K. Cloning and sequencing of the gene encoding a novel lysine-specific cysteine proteinase (lys-gingipain) in Porphyromonas gingivalis: Structural relationship with the arginine-specific cysteine proteinase (arg-gingipain). J Biochem 1996; 120: 398-406.
9. Lantz MS, Allen RD, Duck LW, Blume JL, Switalski LM, Hook M. Identification of Porphyromonas gingivalis components that mediate its interactions with fibronectin. J Bacteriol 1991; 173: 4263-70.
10. Imamura T, Pike RN, Potempa J, Travis J. Pathogenesis of periodontitis: A major arginine-specific cysteine proteinase from Porphyromonas gingivalis induces vascular permeability enhancement through activation of the kallikrein/kinin pathway. J Clin Invest 1994; 94: 361-7.
11. Nakayama K, Kadowaki T, Okamoto K, Yamamoto K. Construction and characterization of arginine-specific cysteine protease (arg-gingipain)-deficient mutants of Porphyromonas gingivalis. Evidence for significant contribution of arg-gingipain to virulence. J Biol Chem 1995; 270: 23619-26.
12. Schenkein H. The effect of periodontal proteolytic Bacteriodes spp. on proteins of the human complement system. J Periodont Res 1998; 23: 62-9.
13. Graves DT, Jiang Y. Chemokines, a family of chemotactic cytokines. Crit Rev Oral Biol Med 1995; 6: 109-18.
14. Kesavalu L, Holt SC, Ebersole JL. Trypsin-like activity of Porphyromonas gingivalas as a potential virulence factor in a murine lesion model. Microb Pathog 1996; 20: 1-10.
15. Eckmann L, Kagnoff ME, Fierer J. Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry. Infect Immun 1993; 61: 4569-74.
16. Lamont RJ, Chan A, Belton CM, Izutsu KT, Vasel D, Weinberg A. Porphyromonas gingivalis invasion of epithelial cells. Infect Immun 1995; 63: 3878-85.
17. Ciborowski P, Nishikata M, Allen RD, Lantz MS. Purification and characterization of two forms of a high-molecular weight cysteine protease (porphypain) from Porphyromonas gingivalis. J Bacteriol 1994; 176: 4549-57.
18. Madianos PN, Papapanou PN, Sandros J. Porphyromonas gingivalis infection of oral epithelium inhibits neutrophil transepithelial migration. Infect Immun 1997; 65: 3983-90.
19. Parmely M, Gale A, Clabaugh M, Horvat R, Zhou W-W. Proteolytic inactivation of cytokines by Pseudomonas aeruginosa. Infect Immun 1990; 58: 3009-14.
20. Fletcher J, Reddi K, Poole S, Nair S, Henderson B, Tabona P, Wilson M. Interactions between periodontopathic bacteria and cytokines. J Periodontal Res 1997; 32: 200-5.