Design, synthesis and biological evaluation of aryl-substituted sialyl Lewis X mimetics prepared via cross-metathesis of C-fucopeptides

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 5, 1999, Pages 773-788

  Huwe, Christoph M ^a   Woltering, Thomas J ^a   Jiricek, Jan ^a   Weitz Schmidt, Gabriele ^b   Wong, Chi Huey ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUND; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; PADGEM PROTEIN; PEPTIDE DERIVATIVE; PHENYL GROUP; POLYSACCHARIDE; RUTHENIUM;

ARTICLE; BINDING AFFINITY; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

CARBOHYDRATE SEQUENCE; DRUG DESIGN; FUCOSE; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; OLIGOSACCHARIDES; PEPTIDES; SELECTINS;

EID: 0033135020     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00245-4     Document Type: Article

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