Coordinate Expression of Cytokeratins 7 and 20 in Feline and Canine Carcinomas

Veterinary Pathology

Volumn 36, Issue 3, 1999, Pages 179-190

  Espinosa De Los Monteros, A ^a   Fernandez A ^a   Millan M Y ^b   Rodriguez F ^a   Herraez P ^a   Martin De Las Mulas J ^b  

^a UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

^b UNIVERSITY OF CÓRDOBA   (Spain)

Author keywords

Carcinomas; Cats; CK 20; CK 7; Cytokeratins; Dogs; Immunohistochemistry

Indexed keywords

CANIS FAMILIARIS; FELIDAE; FELIS CATUS;

CYTOKERATIN 20; CYTOKERATIN 7; INTERMEDIATE FILAMENT PROTEIN; KERATIN; MONOCLONAL ANTIBODY;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLADDER; CARCINOMA; CAT; CAT DISEASE; CHEMISTRY; DOG; DOG DISEASE; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HYPOPHYSIS; IMMUNOHISTOCHEMISTRY; LARGE INTESTINE; LIVER; MALE; OVARY; PANCREAS TUMOR; PATHOLOGY; REFERENCE VALUE; STOMACH; TONGUE; UDDER;

ANIMALS; ANTIBODIES, MONOCLONAL; CARCINOMA; CAT DISEASES; CATS; DOG DISEASES; DOGS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT PROTEINS; INTESTINE, LARGE; KERATIN-20; KERATIN-7; KERATINS; LIVER; MALE; MAMMARY GLANDS, ANIMAL; OVARY; PANCREATIC NEOPLASMS; PITUITARY GLAND; REFERENCE VALUES; STOMACH; TONGUE; URINARY BLADDER;

EID: 0033125291     PISSN: 03009858     EISSN: None     Source Type: Journal    
DOI: 10.1354/vp.36-3-179     Document Type: Article

References (38)

1. Baars JH, De Ruijter JL, Smedts F, van Niekerk CC, Poels LG, Seldenrijk CA, Ramaekers FC: The applicability of a keratin 7 monoclonal antibody in routinely Papanicolaou-stained cytologic specimens for the differential diagnosis of carcinomas. Am J Clin Pathol 101: 257-261, 1994
2. Bartek J, Bartkova J, Taylor-Papadimitriou J, Rejthar A, Kovarik J, Lukas Z, Voijtesek B: Differential expression of keratin 19 in normal human epithelial tissues revealed by monospecific monoclonal antibodies. Histochem J 18: 565-575, 1986
3. Cooper D, Schermer A, Sun TT: Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: strategies, applications, and limitations. Lab Invest 52:243-256, 1985
4. Czernobilsky B, Moll R, Franke WW, Dallenbach-Hellweg G, Hohlweg-Majert P: Intermediate filaments of normal and neoplastic tissues of the female genital tract with emphasis on problems of differential tumor diagnosis. Pathol Res Pract 179:31-37, 1984
5. Debus E, Moll R, Franke WW, Weber K, Osborn M: Immunohistochemical distinction of human carcinomas by cytokeratin typing with monoclonal antibodies. Am J Pathol 114:121-130, 1984
6. Gown AM, Vogel AM: Monoclonal antibodies to human intermediate filament proteins. II. Distribution of filament protein in normal human tissue. Am J Pathol 114: 309-321, 1984
7. Harnden P, Allam A, Joyce AD, Patel A, Selby P, Southgate J: Cytokeratin 20 expression by non-invasive transitional cell carcinomas: potential for distinguishing recurrent from non-recurrent disease. Histopathology 27: 169-174, 1995
8. Ivanyi D, Minke JMHM, Hageman PC, Groeneveld E, van Doornewaard G: Patterns of expression of feline cytokeratins in healthy epithelia and mammary carcinoma cells. Am J Vet Res 53:304-314, 1992
9. Lehto VR Pontén J: Tumor markers in human biopsy material. Acta Oncol 28:743-762, 1989
10. Leong ASY: Diagnostic immunohistochemistry. Problems and solutions. Pathology 24:1-4, 1992
11. Loy TS, Calaluce RD: Utility of cytokeratin immunostaining in separating pulmonary adenocarcinomas from colonie adenocarcinomas. Am J Clin Pathol 102:764-767, 1994
12. Martín de las Mulas J, Espinosa de los Monteros A, Carrasco L, van Niel M, Fernández A: Immunohistochemical distribution pattern of intermediate filament proteins in 50 feline neoplasms. Vet Pathol 32:692-701, 1995
13. Miettinen M: Keratin 20: immunohistochemical marker for gastrointestinal, urothelial, and Merkel cell carcinomas. Mod Pathol 8:384-388, 1995
14. Moch H, Oberholzer M, Dalquen P, Wegmann W, Gudat F: Diagnostic tools for differentiating between pleural mesothelioma and lung adenocarcinoma in paraffin embedded tissue. I. Immunohistochemical findings. Virchows Arch A Pathol Anat 423:19-27, 1993
15. Moll R, Franke WW, Schiller DL, Geiger B, Krepler R: The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 31:11-24, 1982
16. Moll R, Levy R, Czernobilsky B, Hohlweg-Majert R Dallenbach-Hellweg G, Franke WW: Cytokeratins of normal epithelia and some neoplasms of the female genital tract. Lab Invest 49:599-610, 1983
17. Moll R, Löwe A, Laufer J, Franke WW: Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies. Am J Pathol 140:427-447, 1992
18. Moll R, Schiller DL, Franke WW: Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns. J Cell Biol 111:567-580, 1990
19. Moll R, Zimbelmann R, Goldschmidt MD, Keith M, Laufer J, Kasper M, Koch PJ, Franke WW: The human gene encoding cytokeratin 20 and its expression during fetal development and in gastrointestinal carcinomas. Differentiation 53:75-93, 1993
20. Nagle RB, McDaniel KM, Clark VA, Payne CM: The use of antikeratin antibodies in the diagnosis of human neoplasms. Am J Clin Pathol 79:458-466, 1983
21. Osborn M, van Lessen G, Weber K, Kloppel G, Altmannsberger M: Differential diagnosis of gastrointestinal carcinomas by using monoclonal antibodies specific for individual keratin polypeptides. Lab Invest 55:497-504, 1986
22. Osborn M, Weber K: Tumor diagnosis by intermediate filament typing: a novel tool for surgical pathology. Lab Invest 48:372-394, 1983
23. Pruss RM, Mirsky R, Raff MC, Thorpe R, Dowding AJ, Anderton BH: All classes of intermediate filaments share a common antigenetic determinant defined by a monoclonal antibody. Cell 27:419-428, 1981
24. Quinlan RA, Schiller DL, Hatzfeld M, Achtstaetter T, Moll R, Jorcano JL, Magin TM, Franke WW: Patterns of expression and organization of cytokeratin intermediate filaments. Ann NY Acad Sci 455:282-306, 1985
25. Ramaekers F, Huysmans A, Moesker O, Kant A, Jap P, Herman C, Vooijs GP: Monoclonal antibody to keratin filaments, specific for glandular epithelia and their tumors. Use in surgical pathology. Lab Invest 49:353-361, 1983
26. Ramaekers F, Huysmans A, Schaart G, Moesker O, Vooijs P: Tissue distribution of keratin 7 as monitored by a monoclonal antibody. Exp Cell Res 170:235-249, 1987
27. Ramaekers F, van Niekerk C, Poels L, Schaafsma E, Huijsmans A, Robben H, Schaart G, Vooijs P: Use of monoclonal antibodies to keratin 7 in differential diagnosis of adenocarcinomas. Am J Pathol 136:641-655, 1990
28. Savera AT, Torres FX, Linden MD, Bacchi CE, Gown AM, Zarbo RJ: Primary versus metastatic pulmonary adenocarcinoma. An immunohistochemical study using villin and cytokeratins 7 and 20. Appl Immunohistochem 4:86-94, 1996
29. Schröeder S, Wodzynski A, Padberg B: Cytokeratin expression of benign and malignant epithelial thyroid tumours. An immunohistochemical study of 154 neoplasias using 8 different monoclonal anti-cytokeratin antibodies. Pathologe 17:425-432, 1996
30. Tsubura A, Okada H, Senzaki L, Hatano T, Morii S: Keratin expression in the normal breast and in breast carcinoma. Histopathology 18:517-522, 1991
31. Ueda G, Sawada M, Ogawa H, Tanizawa O, Tsujimoto M: Immunohistochemical study of cytokeratin 7 for the differential diagnosis of adenocarcinomas in the ovary. Gynecol Oncol 51:219-223, 1993
32. Van Niekerk CC, Jap PHK, Ramaekers FCS, van de Molengraft F, Poels LG: Immunohistochemical demonstration of keratin 7 in routinely fixed paraffin-embedded human tissues. J Pathol 165:145-152, 1991
33. Vos JH, van den Ingh TSGAM, de Neijs M, van Mil FN, Ivanyi D, Ramaekers FCS: Immunohistochemistry with keratin and smooth muscle actin monoclonal antibodies in canine digestive tract and extramural glands. J Vet Med A 39:241-257, 1992
34. Vos JH, van den Ingh TSGAM, de Neijs M, van Mil FN, Ivanyi D, Ramaekers FCS: Immunohistochemistry with keratin monoclonal antibodies in canine tissues: urogenital tract, respiratory tract, (neuro-)endocrine tissues, chorioid plexus and spinal cord. J Vet Med A 39:721-740, 1992
35. Vos JH, van den Ingh TSGAM, Misdorp W, Molenbeek RF, van Mil FN, Rutteman GR, Ivanyi D, Ramaekers FCS: Immunohistochemistry with keratin, vimentin, desmin and alpha-smooth muscle actin monoclonal antibodies in canine mammary gland: malignant mammary tumours. Vet Q 15:96-102, 1993
36. Wang NP, Zee S, Zarbo RJ, Bacchi CE, Gown AM: Coordinate expression of cytokeratins 7 and 20 defines unique subsets of carcinomas. Appl Immunohistochem 3:99-107, 1995
37. Wauters C, Smedts F, Gerrits LG, Bosman FT, Ramaekers PCS: Keratins 7 and 20 as diagnostic markers of carcinomas metastatic to the ovary. Hum Pathol 26:852-855, 1995
38. World Health Organization: International Histological Classification of Tumours in Domestic Animals. World Health Organization, Geneva, Switzerland, 1974