Physical training as an adjunct therapy in patients with congestive heart failure: Patient selection, training protocols, results, and future directions

Current Cardiology Reports

Volumn 1, Issue 1, 1999, Pages 38-46

  Hambrecht, R ^a   Gielen, S ^a   Schuler, G ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CLASSIFICATION; CONGESTIVE HEART FAILURE; FORECASTING; HEART ARRHYTHMIA; HEART VENTRICLE FUNCTION; HUMAN; KINESIOTHERAPY; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; RISK FACTOR; SKELETAL MUSCLE; SUDDEN DEATH; SURVIVAL;

ARRHYTHMIA; DEATH, SUDDEN, CARDIAC; EXERCISE THERAPY; FORECASTING; HEART FAILURE, CONGESTIVE; HUMANS; MUSCLE, SKELETAL; RISK FACTORS; SURVIVAL ANALYSIS; VENTRICULAR DYSFUNCTION;

EID: 0033123055     PISSN: 15233782     EISSN: 15343170     Source Type: Journal    
DOI: 10.1007/s11886-999-0041-9     Document Type: Article

References (72)

1. Sullivan MJ, Higginbotham MB, Cobb FR: Exercise training in patients with severe left ventricular dysfunction: Hemodynamic and metabolic effects. Circulation 1988, 78:506-515.
2. Coats AJS, Adamopoulos S, Meyer TE, et al.: Effects of physical training in chronic heart failure. Lancet 1990, 335:63-66.
3. Hambrecht R, Niebauer J, Fiehn E, et al.: Physical training in patients with stable chronic heart failure: Effects on cardiorespiratory fitness and ultrastructural abnormalities of leg muscle. J Am Coll Cardiol 1995, 25:1239-1249.
4. Adamopoulos S, Coats AJS, Brunotte F, et al.: Physical training improves skeletal muscle metabolism in patients with chronic heart failure. J Am Coll Cardiol 1993, 21:1101-1106.
5. Giannuzzi P, Temporelli P, Corrà U, et al.: Attenuation of unfavorable remodeling by exercise training in postinfarction patients with left ventricular dysfunction: Results of the Exercise in Left Ventricular Dysfunction (ELVD) Trial. Circulation 1997, 96:1790-1797.
6. Dubach P, Myers J, Dziekan G, et al.: Effect of exercise training on myocardial remodeling in patients with reduced left ventricular function after myocardial infarcation. Circulation 1997, 95:2060-2067.
7. Wilson JR, Groves J, Rayos G: Circulatory status and response to cardiac rehabilitation in patients with heart failure. Circulation 1996, 94:1567-1572.
8. Demopoulos L, Bijou R, Fergus I, et al.: Exercise training in patients with severe congestive heart failure: Enhancing peak aerobic capacity while minimizing the increase in ventricular wall stress. J Am Coll Cardiol 1997, 29:597-603.
9. Kavanagh T, Myers MG, Baigrie RS, et al.: Quality of life and cardiorespiratory function in chronic heart failure: Effects of 12 months aerobic training. Heart 1996, 76:42-49.
10. Hambrecht R, Fiehn E, Yu J, et al.: Effects of endurance training on mitochondrial ultrastructure and fiber type distribution in skeletal muscle of patients with stable chronic heart failure. J Am Coll Cardiol 1997, 29:1067-1073.
11. Stratton JR, Dunn J F, Adamopoulos S, et al.: Training partially reverses skeletal muscle metabolic abnormalities during exercise in heart failure. J Appl Physiol 1994, 76:1575-1582.
12. Terjung RL: Peripherial adaptions in skeletal muscle induced by exercise training. Heart Failure 1988, 3:93-100.
13. Hornig B, Maier V, Drexler H: Physical training improves endothelial function in patients with chronic heart failure. Circulation 1996, 93:210-214.
14. Katz SD, Yuen J, Bijou R, LeJemtel TH: Training improves endothelium-dependent vasodilation in resistance vessels of patients with heart failure. J Appl Physiol 1997, 82:1488-1492.
15. Hambrecht R, Fiehn E, Weigl C, et al.: Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure. Circulation 1998, 98:2709-2715.
16. Magnusson G, Gordon A, Kaijser L, et al.: High intensity knee extensor training in patients with chronic heart failure. Eur Heart J 1996, 17:1048-1055.
17. Koch M, Douard H, Broustet JP: The benefit of graded physical exercise in chronic heart failure. Chest 1998, 101: 231S-235S.
18. Piepoli M, Flather M, Coats AJS: Overview of studies of exercise training in chronic heart failure: The need for a prospective randomized multicentre European trial. Eur Heart J 1998, 19:830-841.
19. Jette M, Heller R, Landry F, Blümchen G: Randomized 4-week exercise program in patients with impaired left ventricular function. Circulation 1991, 84:1561-1567.
20. Ehsani AA, Biello DR, Schultz J, et al.: Improvement of left ventricular contractile function by exercise training in patients with coronary artery disease. Circulation 1986, 74:350-358.
21. Schuler G, Hambrecht R, Schlierf G, et al.: Myocardial perfusion and regression of coronary artery disease in patients on a regime of intensive physical exercise and low fat diet. J Am Coll Cardiol 1992, 19:34-42.
22. Schuler G, Hambrecht R, Schlierf G, et al.: Regular physical exercise and low-fat diet: Effects on progression of coronary artery disease. Circulation 1992, 86:1-11.
23. Galli M, Marcassa C, Bolli R, et al.: Spontaneous delayed recovery of perfusion and contraction after the first five weeks following anterior infarction: Evidence for the presence of hybernating myocardium in the infarcted area. Circulation 1994, 90:1386-1396.
24. Willich S, Lewis M, Löwel H, et al.: Physical exertion as a trigger of acute myocardial infarction. N Engl J Med 1993, 329:1684-1690.
25. Niebauer J, Hambrecht R, Hauer K, et al.: Identification of patients at risk during swimming by holter monitoring. Am J Cardiol 1994, 74:651-656.
26. Ornish D, Brown SE, Scherwitz LW, et al.: Can lifestyle changes reverse coronary heart disease? Lancet 1990, 336:129-133.
27. Jugdutt BI, Michorowski BL, Kappagoda CT: Exercise training after anterior Q wave myocardial infarction: Importance of regional left ventricular function and topography. J Am Coll Cardiol 1988, 12:362-372.
28. Arvan S: Exercise performance of high risk acute myocardial infarction patient after cardiac rehabilitation. Am J Cardiol 1988, 62:197-201.
29. Belardinelli R, Georgiou D, Scocco V, et al.: Low intensity exercise training in patients with chronic heart failure. J Am Coll Cardiol 1995, 26:975-982.
30. Kiilavuori K, Sovijärvi A, Näveri H, et al.: Effect of physical training on exercise capacity and gas exchange in patients with chronic heart failure. Chest 1996, 110:985-991.
31. Meyer K, Samek L, Schwaibold M, et al.: Physical response to different modes of interval exercise in patients with chronic heart failure: Application to exercise training. Eur Heart J 1996, 17:1040-1047.
32. Meyer TE, Casadei B, Coats AJS, et al.: Angiotensin-converting enzyme inhibition and physical training in heart failure. J Intern Med 1991, 230:407-413.
33. The Captopril-Digoxin Multicenter Research Group: Comparative effects of therapy with captopril and digoxin in patients with mild to moderate heart failure. JAMA 1988, 259:539-544.
34. Demopoulos L, Yeh M, Gentilucci M, et al.: Nonselective β-adrenergic blockade with carvedilol does not hinder the benefits of exercise training in patients with congestive heart failure. Circulation 1997, 95:1764-1767.
35. Franciosa JA, Park M, Levine TB: Lack of correlation between exercise capacity and indexes of resting left ventricular per formance in heart failure. Am J Cardiol 1981, 47:33-39.
36. Harrington D, Coats AJS: Mechanisms of exercise intolerance in congestive heart failure. Curr Opin Cardiol 1997, 12:224-232.
37. Wilson JR, Mancini DM, Dunkman WB: Exertional fatigue due to skeletal muscle dysfunction in patients with heart failure. Circulation 1993, 87:470-475.
38. Mancini DM, Coyle E, Coggan A, et al.: Contribution of intrinsic skeletal muscle changes to 31-P NMR skeletal muscle met abolic abnormalities in patients with chronic heart failure. Circulation 1989, 80:1338-1346.
39. Sullivan MJ, Green HJ, Cobb FR: Skeletal muscle biochemistry and histology in ambulatory patients with long term heart failure. Circulation 1990, 81:518-527.
40. Drexler H, Riede U, Münzel T, et al.: Alterations of skeletal muscle in chronic heart failure. Circulation 1992, 85:1751-1759.
41. Sullivan MJ, Green HJ, Cobb FR: Altered skeletal muscle metabolic response to exercise in chronic heart failure. Circulation 1991, 84:1597-1607.
42. Mancini DM, Walter G, Reichek N, et al.: Contribution of skeletal muscle atrophy to exercise intolerance and altered mus cle metabolism in heart failure. Circulation 1992, 85:1364-1373.
43. Massie BM, Conway M, Yonge R, et al.: Skeletal muscle metabolism in patients with congestive heart failure: Relation to clinical severity and blood flow. Circulation 1987, 78:1009-1019.
44. Stratton JR, Kemp GJ, Daly RC, et al.: Effects of cardiac transplantation on bioenergetic abnormalities of skeletal muscle in congestive heart failure. Circulation 1994, 89:1624-1631.
45. Adams V, Yu J, Möbius-Winkler S, et al.: Increased nitric oxide synthase in skeletal muscle biopsies from patients with chronic heart failure. Biochem Mol Med 1997, 61152-160.
46. Hambrecht R, Adams V, Gielen S, et al.: Exercise intolerance in patients with chronic heart failure and increased expression of inducible nitric oxide synthase in the skeletal muscle. J Am Coll Cardiol 1999, 33:174-179.
47. Minotti JR, Johnson EC, Hudson TL, et al.: Skeletal muscle response to exercise training in congestive heart failure. J Clin Invest 1990, 86:751-758.
48. Poole-Wilson PA, Ferrari R: Role of skeletal muscle in the syndrome of chronic heart failure. J Mol Cell Cardiol 1996, 28:2275-2285.
49. Carr J, Stevenson L, Walden J, Heber D: Prevalence and hemodynamic correlates of malnutrition in severe congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol 1989, 63:709-713.
50. Piepoli M, Clark AL, Coats AJS: Muscle metaboreceptors in hemodynamic, autonomic and ventilatory responses to exercise in men. Am J Physiol 1995, 269:H1428-H1436.
51. Tibes U: Reflex inputs to the cardiovascular and respiratory centers from dynamically working canine muscle. Circ Res 1977, 41: 332-341.
52. Piepoli M, Clark AL, Volterrani M, et al.: Contribution of muscle afferents to the hemodynamic, autonomic, and ventilatory responses to exercise in patients with chronic heart failure: Effects of physical training. Circulation 1996, 93:940-952.
53. Ferguson DW, Berg WJ, Sanders JS: Clinical and hemodynamic correlates of sympathetic nerve activity in normal humans and patients with heart failure. J Am Coll Cardiol 1990, 16:1125-1134.
54. Levine B, Kalman J, Mayer L, et al.: Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med 1990, 323:236-241.
55. Swan JW, Walton C, Godsland IE, et al.: Insulin resistance in chronic heart failure. Eur Heart J 1994, 15:1528-1532.
56. Kröncke KD, Fehsel K, Kolb-Bachofen V: Nitric oxide: Cytotoxicity versus cytoprotection: How, why, when, and where. Nitric Oxide: Biology and Chemistry 1997, 1:107-120.
57. Förstermann U, Closs EI, Pollock JS, et al.: Nitric oxide synthase isoenzymes: Characterization, purification, molecular cloning, and functions. Hypertension 1994, 23:1121-1131.
58. Sullivan MJ, Knigth JD, Higgenbotham MB, Cobb FR: Relation between central and peripherial hemodynamics during exercise in patients with chronic heart failure. Circulation 1989, 80:769-781.
59. Dubach P, Myers J, Dzienkan G, et al.: Effect of high intensity exercise training on central hemodynamic response to exercise in men with reduced left ventricular function. J Am Coll Cardiol 1997, 29:1591-1598.
60. Kubo N, Ohmura N, Nakada I, et al.: Exercise training induces left ventricular enlargement in patients with left ventricular dysfunction after anterior myocardial infarction. Circulation 1997, 96:I-345.
61. Belardinelli R, Georgiou D, Cianci G, et al.: Exercise training improves left ventricular diastolic filling in patients with dilated cardiomyopathy. Circulation 1995, 91:2775-2784.
62. Hambrecht R, Fiehn E, Yu J, et al.: Changes in central and peripheral hemodynamics induced by long-term physical exercise training in patients with chronic heart failure. J Am Coll Cardiol 1998, 31 (suppl A):197A.
63. Katz SD, Schwarz M, Yuen J, LeJemtel TH: Impaired acetylcholine-mediated vasodilation in patients with congestive heart failure: Role of endothelium-derived vasodilating and vasoconstricting factors. Circulation 1993, 88:55-61.
64. Katz SD, Biasucci L, Sabba C, et al.: Impaired endotheliummediated vasodilation in the peripheral vasculature of patients wih congestive heart failure. J Am Coll Cardiol 1992, 19:918-925.
65. Coats AJS, Adamopoulos S, Radaelli A, et al.: Controlled trial of physical training in chronic heart failure: Exercise performance, hemodynamics, ventilation, and autonomic function. Circulation 1992, 85:2119-2131.
66. Kiilavuori K, Toivonen L, Näveri H, Leinonen H: Reversal of autonomic derangements by physical training in chronic heart failure assessed by heart rate variability. Eur Heart J 1995, 16:490-495.
67. Cohen-Solal A: Improving exercise tolerance in patients with chronic heart failure: Should we treat the heart or the periphery? Eur Heart J 1989, 10: 866-871.
68. Mancini DM, Henson D, LaManca J, et al.: Benefit of selective respiratory muscle training on exercise capacity in patients with chronic congestive heart failure. Circulation 1995, 91:320-329.
69. Belardinelli R, Georgiou D, Cianci G, Purcaro A: Effects of exercise training on left ventricular filling at rest and during exercise in patients with ischemic cardiomyopathy and severe left ventricular systolic dysfunction. Am Heart J 1996, 132:61-70.
70. Keteyian SJ, Levine AB, Brawner CA, et al.: Exercise training in patients with heart failure: a randomized controlled trial. Ann Intern Med 1996, 124:1051-1057.
71. Meyer K, Schwaibold M, Westbrook S, et al.: Effects of exercise training and activity restriction on 6-minute walking test performance in patients with chronic heart failure. Am Heart J 1997, 133:447-453.
72. Sullivan MJ, Higginbotham MB, Cobb FR: Exercise training in patients with chronic heart failure delays ventilatory anaerobic threshold and improves submaximal exercise performance. Circulation 1989, 79:324-329.