Detailed localization of photoreceptor guanylate cyclase activating protein-1 and -2 in mammalian retinas using light and electron microscopy

Experimental Eye Research

Volumn 68, Issue 4, 1999, Pages 465-473

  Kachi, Shu ^a   Nishizawa, Yuji ^a   Olshevskaya, Elena ^b   Yamazaki, Akio ^b,c   Miyake, Yozo ^a   Wakabayashi, Takashi ^a   Dizhoor, Alexander ^b,c   Usukura, Jiro ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b WAYNE STATE UNIVERSITY   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

GCAP; Guanylate cyclase; Immunocytochemistry; Photoreceptors; Retina

Indexed keywords

GUANYLATE CYCLASE ACTIVATOR;

ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME ANALYSIS; ENZYME LOCALIZATION; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; MICROSCOPY; PHOTORECEPTOR; PRIORITY JOURNAL;

EID: 0033120924     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1998.0629     Document Type: Article

References (25)

1. Baylor, D. (1996). How photons start vision. Proc. Natl. Acad. Sci. USA 93, 560-5.
2. Cuenca, N., Lopez, S., Howes, K. and Kolb, H. (1998). The localization of guanylyl cyclase-activating proteins in the mammalian retina. Invest. Ophthalmol Vis. Sci. 39, 1243-50.
3. 2+- Induced 'activator-to-inhibitor' transition. J. Biol. Chem. 271, 19346-50.
4. Dizhoor, A. M., Lowe, D. G., Olshevskaya, E. V., Laura, R. P. and Hurley, J. B. (1994). The human photoreceptor membrane guanylyl cyclase, retgc, is present in outer segments and is regulated by calcium and a soluble activator. Neuron 12, 1345-52.
5. 2+-binding protein activating photoreceptor guanylyl cyclase. J. Biol. Chem. 270, 25200-6.
6. Dizhoor, A.M., Boikov, S. and Olshevskaya, E.V. (1998). Constitutive activation of photoreceptor guanylate cyclase by Y99C mutant of GCAP-1 : Possible role in causing human autosomal dominant cone degeneration. J. Biol. Chem. 273, 17311-14.
7. Frins, S., Bönigk, W., Müller, F., Kellner, R. and Koch, K. W. (1996). Functional characterization of a guanylyl cyclase-activating protein from vertebrate rods. Cloning, heterologous expression, and localization. J. Biol. Chem. 271, 8022-7.
8. Gorczyca, W. A., Polans, A. S., Surgucheva, I. G., SubBaraya, I., Baehr, W. and Palczewski, K. (1995). Guanylyl cyclase. A calcium-sensitive regulator of phototransduction. J. Biol. Chem. 270, 22029-36.
9. Howes, K., Bronson, J. D., Dang, Y. L., Li, N., Zhang, K., Ruiz, C., Helekar, B., Lee, M., Subbaraya, I., Chen, J. and Baehr, W. (1998). Gene array and expression of mouse retina guanylate cyclase activating proteins 1 and 2. Invest. Ophthalmol Vis. Sci. 39, 867-75.
10. Koch, K. W. and Stryer, L. (1988). Highly cooperative feedback control of retinal rod guanylate cyclase by calcium ions. Nature 334, 64-6.
11. 2+-binding protein related to mammalian guanylate- Cyclase-activating proteins. Eur. J. Biochem. 252, 591-9.
12. Liu, X., Seno, K., Nishizawa, Y., Hayashi, F., Yamazaki, A., Matsumoto, H., Wakabayashi, T. and Usukura, J. (1994). Ultrastructural localization of retinal guanylate cyclase in human and monkey retinas. Exp. Eye Res. 59, 761-8.
13. Lolley, R. N. and Racz, E. (1982). Calcium modulation of cyclic GMP synthesis in rat visual cells. Vis. Res. 22, 1481-6.
14. Lolley, R. N. and Lee, R. H. (1990). Cyclic GMP and photoreceptor function. FASEB. J. 4, 3001-8.
15. Milam, A. H., Dacey, D.M., Dizhoor, A.M. (1993). Recoverin immunoreactivity in mammalian cone bipolar cells. Vis. Neurosci. 9, 10, 1-12.
16. Olshevskaya, E. V., Hughes, R. E., Hurley, J. B. and Dizhoor, A. M. (1997). Calcium binding, but not a calcium- Myristoyl switch, controls the ability of guanylyl cyclase-activating protein GCAP-2 to regulate photoreceptor guanylyl cyclase. J. Biol. Chem. 272, 14327- 33.
17. Otto-Bruc, A., Fariss, R. N., Haeseleer, F., Huang, J., Buczylko, J., Surgucheva, I., Baehr, W., Milam, A. H. and Palczewski, K. (1997). Localization of guanylate cyclase-activating protein 2 in mammalian retinas. Proc. Natl. Acad. Sc. USA 94, 4727-32.
18. Palczewski, K., Subbaraya, I., Gorczyca, W. A., Helekar, B. S., Ruiz, C. C., Ohguro, H., Huang, J., Zhao, X., Crabb, J. W., Johnson, R. S., Walsh, K. A., Grey-Keller, M. P., Detwiler, P. B. and Baehr, W. (1994). Molecular cloning and characterization of retinal photoreceptor guanylyl cyclase-activating protein. Neuron 13, 395- 404.
19. Papermaster, D.S. and Dreyer, W. J. (1974). Rhodopsin content in the outer segment membranes of bovine and frog retinal rods. Biochemistry 13, 2438-44.
20. Payne, A. M., Downes, S. M., Bessant, D. A., Taylor, R., Holder, G. E., Warren, M. J., Bird, A. C. and BhattaCharya, S. S. (1998). A mutation in guanylate cyclase activator 1A (GUCA1A) in an autosomal dominant cone dystrophy pedigree mapping to a new locus on chromosome 6p21.1. Hum. Mol. Genet. 7, 273-7.
21. Pugh, E. N., Jr., Duda, T., Sitaramayya, A. and Sharma, R. K. (1997). Photoreceptor guanylate cyclases: A review. Biosci. Reports 17, 429-72.
22. Rudnicka-Nawrot, M., Surgucheva, I., Hulmes, J. D., Haeseleer, F., Sokal, I., Crabb, J. W., Baehr, W. and Palczewski, K. (1998). Changes in biological activity and folding of guanylate cyclase-activating protein 1 as a function of calcium. Biochemistry 37, 248-57.
23. Subbaraya, I., Ruiz, C. C., Helekar, B. S., Zhao, X., Gorczyca, W. A., Pettenati, M. J., Rao, P. N., Palczewski, K. and Baehr, W. (1994). Molecular characterization of human and mouse photoreceptor guanylate cyclase-activating protein (GCAP) and chromosomal localization of the human gene. J. Biol. Chem. 269, 31080-9.
24. Surguchov, A., Bronson, J. D., Banerjee, P., Knowles, J. A., Ruiz, C., Subbaraya, I., Palczewski, K. and Baehr, W. (1997). The human GCAP 1 and GCAP 2 genes are arranged in tail-to-tail array on the short arm of chromosome 6(p21.1). Genomics 39, 312-22.
25. Usukura, J. and Bok, D. (1987). Changes in the localization and content of opsin during retinal development in the rds mutant mouse: Immuno cytochemistry and immunoassay. Exp. Eye Res. 45, 501-15.