Antigenic variation in Porphyromonas gingivalis ribotypes recognized by serum immunoglobulin G of adult periodontitis patients

Oral Microbiology and Immunology

Volumn 14, Issue 2, 1999, Pages 73-85

  Sims, T J ^a   Ali, R W ^c   Brockman, E S ^a   Skaug, N ^c   Page, Roy C ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c NONE

Author keywords

Cluster analysis; Immunoglobulin G; Periodontitis; Porphyromonas gingivalis; Ribotype; Western blot

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL POLYSACCHARIDE; BACTERIAL PROTEIN; BACTERIAL VACCINE; BACTERIUM ANTIBODY; EPITOPE; IMMUNOGLOBULIN G; K ANTIGENS; MEMBRANE ANTIGEN;

ADULT; ANTIGENIC VARIATION; ARTICLE; BACTERIUM IDENTIFICATION; BLOOD; CLUSTER ANALYSIS; GENETIC VARIABILITY; GENETICS; HUMAN; IMMUNOLOGY; MICROBIOLOGY; NONPARAMETRIC TEST; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; PROTEIN BINDING; WESTERN BLOTTING;

ADULT; ANTIBODIES, BACTERIAL; ANTIGENIC VARIATION; ANTIGENS, BACTERIAL; ANTIGENS, SURFACE; BACTERIAL PROTEINS; BACTERIAL TYPING TECHNIQUES; BACTERIAL VACCINES; BLOTTING, WESTERN; CLUSTER ANALYSIS; EPITOPES; HUMANS; IMMUNOGLOBULIN G; PERIODONTITIS; POLYSACCHARIDES, BACTERIAL; PORPHYROMONAS GINGIVALIS; PROTEIN BINDING; STATISTICS, NONPARAMETRIC; VARIATION (GENETICS);

EID: 0033120786     PISSN: 09020055     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-302X.1999.140201.x     Document Type: Article

References (47)

1. American Academy of Periodontology. Consensus report. Periodontal diseases: pathogenesis and microbial factors. Ann Periodontol 1996: 1: 926-932.
2. Ali RW, Martin L, Haffajee AD, Socransky SS. Detection of identical ribotypes of Porphyromonas gingivalis in patients residing in the United States, Sudan, Romania and Norway. Oral Microbiol Immunol 1997: 12: 106-111.
3. Ali RW, Velcescu C, Jivanescu MC, Lofthus B, Skaug N. Prevalence of 6 putative periodontal pathogens in subgingival plaque samples from Romanian adult periodontitis patients. J Clin Periodontol 1996: 23: 133-139.
4. Chen HA, Johnson BD, Sims TJ, Darveau RP, Moncla BJ, Whitney CW, Engel D, Page RC. Humoral immune responses to Porphyromonas gingivalis before and following therapy in rapidly progressive periodontitis patients. J Periodontol 1991: 62: 781-791.
5. Curtis MA. Analysis of the protease and adhesin domains of the PrpRI of Porphyromonas gingivalis. J Periodont Res 1997: 32: 133-139.
6. Curtis MA, Aduse O-J, Slaney JM, Rangarajan M, Booth V, Cridland J, Shepherd P. Characterization of an adherence and antigenic determinant of the ArgI protease of Porphyromonas gingivalis which is present on multiple gene products. Infect Immun 1996: 64: 2532-2539.
7. DeCarlo AA, Harber GJ. Hemagglutinin activity and heterogeneity of related Porphyromonas gingivalis proteinases. Oral Microbiol Immunol 1997: 12: 47-56.
8. Ebersole JL, Steffen MJ. Human antibody responses to outer envelope antigens of Porphyromonas gingivalis serotypes. J Periodont Res 1995: 30: 1-14.
9. Evans RT, Klausen B, Sojar HT, Bedi GS, Sfintescu C, Ramamurthy NS, Golub LM, Genco RJ. Immunization with Porphyromonas (Bacteroides) gingivalis fimbriae protects against periodontal destruction. Infect Immun 1992: 60: 2926-2935.
10. Greenstein G, Lamster I. Bacterial transmission in periodontal diseases: a critical review. J Periodontol 1997: 68: 421-431.
11. Grossi SG, Zambon JJ, Ho AW, Koch G, Dunford RG, Machtei EE, Norderyd OM, Genco RJ. Assessment of risk for periodontal disease. I. Risk indicators for attachment loss. J Periodontol 1994: 65: 260-267.
12. Gunsolley JC, Tew JG, Gooss C, Marshall DR, Burmeister JA, Schenkein HA. Serum antibodies to periodontal bacteria. J Periodontol 1990: 61: 412-419.
13. Han N, Whitlock J, Progulske F-A. The hemagglutinin gene A (hagA) of Porphyromonas gingivalis 381 contains four large, contiguous, direct repeats. Infect Immun 1996: 64: 4000-4007.
14. Ishikawa I, Nakashima K, Koseki T, Nagasawa T, Watanabe H, Arakawa S, Nitta H, Nishihara T. Induction of the immune response to periodontopathic bacteria and its role in the pathogenesis of periodontitis. Periodontol 2000 1997: 14: 79-111.
15. Kojima T, Yano K, Ishikawa I. Relationship between serum antibody levels and subgingival colonization of Porphyromonas gingivalis in patients with various types of periodontitis. J Periodontol 1997: 68: 618-625.
16. Laine ML, Appelmelk BJ, van Winkelhoff AJ. Novel polysaccharide capsular serotypes in Porphyromonas gingivalis. J Periodont Res 1996: 31: 278-284.
17. Laine ML, Appelmelk BJ, van Winkelhoff AJ. Prevalence and distribution of six capsular serotypes of Porphyromonas gingivalis periodonlitis patients. J Dent Res 1997: 76: 1840-1844.
18. Lantz MS. Are bacterial proteases important virulence factors? J Periodont Res 1997: 32: 126-132.
19. Lantz MS. New insights into mechanisms of bacterial pathogenesis in periodontitis. Curr Opin Periodontol 1996: 3: 10-18.
20. Lee JY, Sojar HT, Amano A, Genco RJ. Purification of major fimbrial proteins of Porphyromonas gingivalis. Protein Expression Purification 1995: 6: 496-500.
21. Lee JY, Sojar HT, Bedi GS, Genco RJ. Porphyromonas (Bacteroides) gingivalis fimbrillin: size, amino-terminal sequence, and antigenic heterogeneity. Infect Immun 1991: 59: 383-389.
22. Loos BG, Dyer DW, Whittam TS, Selander RK. Genetic structure of populations of Porphyromonas gingivalis associated with periodontitis and other oral infections. Infect Immun 1993: 61: 204-212.
23. Lopatin DE, Blackburn E. Avidity and titer of immunoglobulin G subclasses to Porphyromonas gingivalis in adult periodontitis patients. Oral Microbiol Immunol 1992: 7: 332-337.
24. M'Enard C, Mouton C. Clonal diversity of the taxon Porphyromonas gingivalis assessed by random amplified polymorphic DNA fingerprinting. Infect Immun 1995 63: 2522-3531.
25. Moller AJR. Microbial examination of root canals and periapical tissues of human teeth. Odontol Tidskr 1966: 74: 1-380.
26. Nagata A, Man-yoshi T, Sato M, Nakamura R. Serological studies of Porphyromonas (Bacteroides) gingivalis and correlation with enzyme activity. J Periodont Res 1991: 26: 184-190.
27. Nakagawa S, Machida Y, Nakagawa T, Fujii H, Yamada S, Takazoe I, Okuda K. Infection by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans, and antibody responses at different ages in humans. J Periodont Res 1994: 29: 9-16.
28. Nakagawa T, Nakagawa S, Ishihara K, Yamada S, Machida Y, Okuda K. Reactive antibodies in sera from pubertal and adult gingivitis patients against various Porphyromonas gingivalis antigens. J Periodont Res 1995: 30: 396-403.
29. Ogawa T. The potential protective immune responses to synthetic peptides containing conserved epitopes of Porphyremonas gingivalis fimbrial protein. J Med Microbiol 1994: 41: 349-358.
30. Ogawa T, McGhee ML, Moldoveanu Z, Hamada S, Mestecky J, McGhee JR, Kiyono H. Bacteroides-specific IgG and IgA subclass antibody-secreting cells isolated from chronically inflamed gingival tissues. Clin Exp Immunol 1989: 76: 103-110.
31. Ogawa T, Tarkowski A, McGhee ML, Moldoveanu Z, Mestecky J, Hirsch HZ, Koopman WJ, Hamada S, McGhee JR, Kiyono H. Analysis of human IgG and IgA subclass antibody-secreting cells from localized chronic inflammatory tissue. J Immunol 1989: 142: 1150-1158.
32. Page RC, Genco R. Mucosal immunity and periodontitis. In: Kiyono, ed. Mucosal immunity. New York: Academic Press, 1996: 437-449.
33. Persson GR, Engel D, Whitney C, Darveau R, Weinberg A, Brunsvold M, Page RC. Immunization against Porphyromonas gingivalis inhibits progression of experimental periodontitis in nonhuman primates. Infect Immun 1994: 62: 1026-1031.
34. Peterman JH, Butler JE. Application of theoretical considerations to the analysis of ELISA data. Biotechniques 1989: 7: 608-815.
35. Schenck K, Helgeland K, Tollefsen T. Antibodies against lipopolysaccharide from Bacteroides gingivalis before and after periodontal treatment. Scand J Dent Res 1987: 95: 112-118.
36. Schenck K, Michaelsen TE. IgG subclass distribution of serum antibodies against lipopolysaccharide from Bacteroides gingivalis in periodontal health and disease. APMIS 1987: 95: 41-46.
37. Schifferle RE. Purification of P. gingivalis polysaccharide and LPS. J Dent Res 1997: 76: 223 (abstr 1675).
38. Schifferle RE, Chen PB, Davern LB, Aguirre A, Genco RJ, Levine MJ. Modification of experimental Porphyromonas gingivalis murine infection by immunization with a polysaccharide-protein conjugate. Oral Microbiol Immunol 1993: 8: 266-271.
39. Sharma A, Nagata H, Hamada N, Sojar HT, Hruby DE, Kuramitsu HK, Genco RJ. Expression of functional Porphyromonas gingivalis fimbrillin polypeptide domains on the surface of Streptococcus gordonii. Appl Environ Microbiol 1996: 62: 3933-3938.
40. Sims TJ, Moncla BJ, Darveau RP, Page RC. Antigens of Actinobacillus actinomycetemcomitans recognized by patientswith juvenile periodontitis and peri-odontally normal subjects. Infect Immun 1991: 59: 913-924.
41. Socransky SS, Haffajee AD, Cugini MA, Smith C, Kent RL. Microbial complexes in subgingival plaque. J Dent Res 1997: 76: 51 (abstr 302).
42. Sojar HT, Hamada N, Genco RJ. Isolation and characterization of fimbriae from a sparsely fimbriated strain of Porphyromonas gingivalis. Appl Environ Microbiol 1997: 63: 2318-2323.
43. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A 1979: 76: 4350-4354.
44. van Winkelhoff AJ, Appelmelk BJ, Kippuw N, de-Graaff J. K-antigens in Porphyromonas gingivalis are associated with virulence. Oral Microbiol Immunol 1993: 8: 259-265.
45. Vasel D, Sims TJ, Bainbridge B, Houston L, Darveau R, Page RC. Shared antigens of Porphyromonas gingivalis and Bacteroides forsythus. Oral Microbiol Immunol 1996: 11: 226-235.
46. Weidner MF, Grenier D, Mayrand D. Proteolytic artifacts in SDS-PAGE analysis of selected periodontal pathogens. Oral Microbiol Immunol 1996: 11: 103-108.
47. Wilton JM, Hurst TJ, Sterne JA. Elevated opsonic activity for Porphyromonas (Bacteroides) gingivalis in serum from patients with a history of destructive periodontal disease. A case: control study. J Clin Periodontol 1993: 20: 563 569.