On-bead combinatorial approach to the design of chiral stationary phases for HPLC

Analytical Chemistry

Volumn 71, Issue 7, 1999, Pages 1278-1284

  Murer, Peter ^a   Lewandowski, Kevin ^a   Svec, Frantisek ^a   Fréchet, Jean M J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANILIDE; PROLINE DERIVATIVE;

ANALYTIC METHOD; ARTICLE; CHEMICAL ANALYSIS; CHIRAL CHROMATOGRAPHY; CHIRALITY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR RECOGNITION;

AMINO ACIDS; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; INDICATORS AND REAGENTS; MICROSPHERES; STEREOISOMERISM;

EID: 0033119511     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac981143v     Document Type: Article

References (66)

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21. For recent reviews, see: Gallop, M. A.; Barrett, R. W.; Dower, W. J.; Fodor, S. P. A.; Gordon, E. M. J. Med. Chem. 1994, 37, 1233-1251, 1386-1401. Terrett, N. K.; Gardner, M.; Gordon, D. W.; Kobylecki, R. J.; Steele, J. Tetrahedron 1995, 51, 8135-8173. Thompson, L. A.; Ellman, J. A. Chem. Rev. 1996, 96, 555-600. Gordon, E. M.; Gallop, M. A.; Patel, D. V. Acc. Chem. Res. 1996, 29, 144-154. Balkenhohl, F.; von dem Bussche- Hünnefeld, C.; Lansky, A.; Zechel, C. Angew. Chem., Int. Ed. Engl. 1996, 35, 2288-2337. Lam, K. S.; Lebl, M.; Krchnak, V. Chem. Rev. 1997, 97, 411-448. Wilson, S. R., Czarnik, A. W., Eds. Combinatorial Chemistry; John Wiley & Sons: New York, 1997.
22. For recent reviews, see: Gallop, M. A.; Barrett, R. W.; Dower, W. J.; Fodor, S. P. A.; Gordon, E. M. J. Med. Chem. 1994, 37, 1233-1251, 1386-1401. Terrett, N. K.; Gardner, M.; Gordon, D. W.; Kobylecki, R. J.; Steele, J. Tetrahedron 1995, 51, 8135-8173. Thompson, L. A.; Ellman, J. A. Chem. Rev. 1996, 96, 555-600. Gordon, E. M.; Gallop, M. A.; Patel, D. V. Acc. Chem. Res. 1996, 29, 144-154. Balkenhohl, F.; von dem Bussche- Hünnefeld, C.; Lansky, A.; Zechel, C. Angew. Chem., Int. Ed. Engl. 1996, 35, 2288-2337. Lam, K. S.; Lebl, M.; Krchnak, V. Chem. Rev. 1997, 97, 411-448. Wilson, S. R., Czarnik, A. W., Eds. Combinatorial Chemistry; John Wiley & Sons: New York, 1997.
23. For recent reviews, see: Gallop, M. A.; Barrett, R. W.; Dower, W. J.; Fodor, S. P. A.; Gordon, E. M. J. Med. Chem. 1994, 37, 1233-1251, 1386-1401. Terrett, N. K.; Gardner, M.; Gordon, D. W.; Kobylecki, R. J.; Steele, J. Tetrahedron 1995, 51, 8135-8173. Thompson, L. A.; Ellman, J. A. Chem. Rev. 1996, 96, 555-600. Gordon, E. M.; Gallop, M. A.; Patel, D. V. Acc. Chem. Res. 1996, 29, 144-154. Balkenhohl, F.; von dem Bussche-Hünnefeld, C.; Lansky, A.; Zechel, C. Angew. Chem., Int. Ed. Engl. 1996, 35, 2288-2337. Lam, K. S.; Lebl, M.; Krchnak, V. Chem. Rev. 1997, 97, 411-448. Wilson, S. R., Czarnik, A. W., Eds. Combinatorial Chemistry; John Wiley & Sons: New York, 1997.
24. For recent reviews, see: Gallop, M. A.; Barrett, R. W.; Dower, W. J.; Fodor, S. P. A.; Gordon, E. M. J. Med. Chem. 1994, 37, 1233-1251, 1386-1401. Terrett, N. K.; Gardner, M.; Gordon, D. W.; Kobylecki, R. J.; Steele, J. Tetrahedron 1995, 51, 8135-8173. Thompson, L. A.; Ellman, J. A. Chem. Rev. 1996, 96, 555-600. Gordon, E. M.; Gallop, M. A.; Patel, D. V. Acc. Chem. Res. 1996, 29, 144-154. Balkenhohl, F.; von dem Bussche- Hünnefeld, C.; Lansky, A.; Zechel, C. Angew. Chem., Int. Ed. Engl. 1996, 35, 2288-2337. Lam, K. S.; Lebl, M.; Krchnak, V. Chem. Rev. 1997, 97, 411-448. Wilson, S. R., Czarnik, A. W., Eds. Combinatorial Chemistry; John Wiley & Sons: New York, 1997.
25. For recent reviews, see: Gallop, M. A.; Barrett, R. W.; Dower, W. J.; Fodor, S. P. A.; Gordon, E. M. J. Med. Chem. 1994, 37, 1233-1251, 1386-1401. Terrett, N. K.; Gardner, M.; Gordon, D. W.; Kobylecki, R. J.; Steele, J. Tetrahedron 1995, 51, 8135-8173. Thompson, L. A.; Ellman, J. A. Chem. Rev. 1996, 96, 555-600. Gordon, E. M.; Gallop, M. A.; Patel, D. V. Acc. Chem. Res. 1996, 29, 144-154. Balkenhohl, F.; von dem Bussche- Hünnefeld, C.; Lansky, A.; Zechel, C. Angew. Chem., Int. Ed. Engl. 1996, 35, 2288-2337. Lam, K. S.; Lebl, M.; Krchnak, V. Chem. Rev. 1997, 97, 411-448. Wilson, S. R., Czarnik, A. W., Eds. Combinatorial Chemistry; John Wiley & Sons: New York, 1997.
26. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace-Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
27. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
28. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
29. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
30. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
31. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
32. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
33. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
34. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
35. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
36. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
37. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
38. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
39. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
40. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
41. For drug discovery, see examples in ref 6. Superconducting materials: Xiang, X.-D.; Sun, X.; Briceno, G.; Lou, Y.; Wang, K. A.; Chang, H.; Wallace- Freedman, W. G.; Chen, S.-W.; Schultz, P. G. Science 1995, 268, 1738. Hsieh-Wilson, L. C.; Xiang, X.-D.; Schultz, P. G. Acc. Chem. Res. 1996, 29, 164. Magnetoresistant materials: Briceno, G.; Chang, H.; Sun, X.; Schultz, P. G., Xiang, X.-D. Science 1995, 270, 273. Phosphors: Sun, X.-D.; Gao, C.; Wang, J.; Xiang, X.-D. Appl. Phys. Lett. 1997, 70, 3353. Danielson, E.; Golden, J. H.; McFarland, E. W.; Reaves, C. M.; Weinberg, W. H.; Wu, X. D. Nature 1997, 389, 944. Metal complexing ligands: Burger, M. T.; Still, W. C. J. Org. Chem. 1995, 60, 7382. Francis, M. B.; Finney, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 1996, 118, 8983-8984. Catalysts: Menger, F. M.; Eliseev, A. V.; Migulin, V. A. J. Org. Chem. 1995, 60, 6666. Liu, G.; Ellman, J. A. J. Org. Chem. 1995, 60, 7712. Gilbertson, S. R., Wang, X. J. Org. Chem. 1996, 61, 434. Gilbertson, S. R.; Wang, X. Tetrahedron Lett. 1996, 37, 6475. Cole, B. M.; Shimizu, K. D.; Krueger, C. A.; Harrity, J. P. A.; Snapper, M. L.; Hoveyda, A. H. Angew. Chem., Int. Ed. Engl. 1996, 35, 1668. Taylor, S. J.; Morken, J. P. Science 1998, 280, 267. Gennari, C.; Ceccarelli, S.; Piarulli, U.; Monalbetti, C. H. G. N.; Jackson, R. F. W. J. Org. Chem. 1998, 63, 5312. Polymers: Brocchini, S.; James, K.; Tangpasuthadol, V.; Kohn, J. J. Am. Chem. Soc. 1997, 119, 4553-4554. Sensors: Dickinson, T. A.; Walt, D. R., White, J.; Kauer, J. S. Anal. Chem. 1997, 69, 3413-3418.
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