Moderate doses of porcine somatotropin do not increase plasma insulin- like growth factor-I (IGF-I) or IGF binding protein-3

Domestic Animal Endocrinology

Volumn 16, Issue 3, 1999, Pages 149-157

  Dunshea, F R ^a   King, R H ^a   Owens, P C ^b   Walton, P E ^c  

^a VIC INSTITUTE OF ANIMAL SCIENCE   (Australia)

^b Div of Hlth Sciences and Nutrition   (Australia)

^c UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ANIMAL; ANIMAL EXPERIMENT; ARTICLE; BLOOD; BODY GROWTH; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FOOD INTAKE; GROWTH RATE; GROWTH, DEVELOPMENT AND AGING; HORMONE ACTION; LACTATION; MALE; METABOLISM; NONHUMAN; NURSING; RANDOMIZED CONTROLLED TRIAL; SWINE; WEANING; WEIGHT GAIN;

ANIMALS; ANIMALS, SUCKLING; GROWTH HORMONE; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; MALE; SWINE; WEANING; WEIGHT GAIN;

ANIMALIA; SUIDAE; SUS SCROFA;

EID: 0033119013     PISSN: 07397240     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0739-7240(99)00010-7     Document Type: Article

References (38)

1. Boyd D.R., Kensinger R.S., Harrell R.J., Bauman D.E. Nutrient uptake and endocrine regulation of milk synthesis in mammary tissue of lactating sows. J Anim Sci. 73:(Suppl. 2):1995;36-56.
2. Campbell R.G., Johnson R.J., Taverner M.R., King R.H. Interrelationships between exogenous porcine somatotropin (pST) administration and dietary protein and energy intake on protein deposition capacity and energy metabolism of pigs. J Anim Sci. 69:1991;1522-1531.
3. Harrell R.J., Thomas M.J., Boyd R.D., Czerwinski S.M., Steele N.C., Bauman D.E. Effect of porcine somatotropin administration in young pigs during the growth phase from 10 to 25 kilograms. J Anim Sci. 75:1997;3152-3160.
4. Buonomo F.C., Klindt J. Ontogeny of growth hormone (GH), insulin-like growth factors (IGF-I and IGF-II) and IGF binding protein-2 (IGFBP-2) in genetically lean and obese swine. Domest Anim Endocrinol. 10:1993;257-265.
5. Matteri R.L., Carroll J.A. Somatotroph function in the neonatal pig. Domest Anim Endocrinol. 14:1997;241-249.
6. Klindt J., Stone R.T. Porcine growth hormone and prolactin Concentrations in the fetus and secretory patterns in the growing pig . Growth. 48:1984;1-5.
7. Owens P.C., Conlon M.A., Campbell R.G., Johnson R.J., King R.H., Ballard F.J. Developmental changes in growth hormone, insulin-like growth factors (IGF-I and IGF-II) and IGF-binding proteins in plasma of young growing pigs. J Endocrinol. 128:1991;439-447.
8. Duchamp C., Butron K.A., Herpin P., Dauncey M.J. Perinatal ontogeny of porcine growth hormone receptor gene expression is modulated by thyroid status. Eur J Endocrinol. 134:1996;524-531.
9. Brameld J.M., Weller P.A., Pell J.M., Buttery P.J., Gilmour R.S. Hormonal control of insulin-like growth factor-1 and growth hormone receptor mRNA expression by porcine hepatocytes in culture. J Endocrinol. 146:1995;239-245.
10. Owens P.C., Johnson R.J., Campbell R.G., Ballard F.J. Growth hormone increases insulin-like growth factor-I (IGF-I) and decreases IGF-II in plasma of growing pigs. J Endocrinol. 124:1990;269-275.
11. Francis G.L., Owens P.C., McNeil K.A., Wallace J.C., Ballard F.J. Purification, amino-acid sequences and assay cross-reactivities of porcine insulin-like growth factor I and II. J Anim Sci. 72:(Suppl. 1):1989;253.
12. Carr J.M., Owens J.A., Grant P.A., Owens P.C., Wallace J.C. Circulating insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs) and tissue mRNA levels of IGFBP-2 and IGFBP-4 in the ovine fetus. J Endocrinol. 145:1995;545-557.
13. Walton P.E., Etherton T.D. Effects of porcine growth hormone and insulin-like growth factor-I (IGF-I) on immunoreactive IGF-binding protein concentration in pigs. J Endocrinol. 120:1989;153-160.
14. Baxter R.C., Martin J.L. Radioimmunoassay of growth hormone-dependent insulin-like growth factor binding protein in human plasma. J Clin Invest. 78:1986;1504-1512.
15. Lawes Agricultural Trust. GENSTAT V, Reference Manual. Clarendon Press, Oxford, UK, 1987.
16. Auldist D.E., Morrish L., Thompson M., King R.H. Response of sows to varying litter size. Proc Nutr Soc Aust. 18:1994;175.
17. Dunaiski V., Dunshea F.R., Clarke I.J., Goddard C., Owens P.C., Walton P.E. Endocrine regulation of somatotropin secretion by IGF-I and IGF-I analogues in pigs. Hennessy D.P., Cranwell P.D. Manipulating Pig Production V. 1995;86 Australian Pig Science Association, Werribee, Australia.
18. 3IGF-I) reduces growth, plasma growth hormone, IGFBP3 and endogenous IGF-I concentration in pigs. J Endocrinol. 155:1997;559-565.
19. Dunshea F.R., Birrell F., Gannon N.J., Kerton D.J., Shaw S.L., Parr R.A. Increased glucose production is not the cause of hyperglycemia during pST treatment of pigs. J Anim Sci. 74:(Suppl. 1):1996;144.
20. Robertson J.G., Walton P.E., Dunshea F.R., Ballard F.J., Belford D.A. Growth hormone but not insulin-like growth factor-I improves wound strength in pigs. Wound Repair Regen. 5:1997;168-174.
21. King R.H., Boyce J.M., Dunshea F.R. The effect of supplemental nutrients on the growth performance of suckling pigs. Aust J Agri Res. 49:1998;883-887.
22. Schnoebelen-Combes S., Louveau I., Postel-Vinay M.C., Bonneau M. Ontogeny of GH receptor and GH-binding protein in the pig. J Endocrinol. 148:1996;249-255.
23. Holl R.W., Snehotta R., Siegler B., Scherbaum W., Heinze E. Binding protein for hormone: Effects of age and weight. Horm Res. 35:1991;190-197.
24. Bernardini S., Spadoni G.L., Povoa G., Boscherini B., Hall K. Plasma levels of insulin-like growth factor binding protein-1, and growth hormone binding protein activity from birth to the third month of life. Acta Endocrinologica. 127:1992;313-318.
25. Harrell D.A., Matitashvili E., Bauman D.E. Effects of exogenous porcine somatotropin on adipose tissue metabolism in young growing pigs. J Anim Sci. 74:(Suppl. 1):1996;143.
26. Wester T.J., Davis T.A., Fioretto M.L., Burrin D.G. Exogenous growth hormone stimulates somatotropic axis function and growth in neonatal pigs. Amer J Physiol. 274:1998;E29-E37.
27. Dunshea F.R., Walton P.E. Potential of exogenous metabolic modifiers for the pig industry. Cranwell P.D., Hennessy D.P. Manipulating Pig Production V. 1995;42-51 Australian Pig Science Association, Werribee, Australia.
28. Morovat A., Burton K.A., Dauncey M.J. Short-term regulation of plasma IGF-I concentration by food intake in young growing pigs. Horm Meta Res. 26:1994;265-269.
29. Campbell R.G., Johnson R.J., King R.H., Taverner M.R., Meisinger D.J. Interaction of dietary protein content and exogenous porcine growth hormone administration on protein and lipid accretion rates in growing pigs. J Anim Sci. 68:1990;3217-3225.
30. Owens P.C., Campbell R.G., Francis G.L., Quinn K.J. Growth hormone, gender and insulin-like growth factors Relationship to growth performance in pigs . J Anim Sci. 72:(Suppl. 1):1994;253.
31. Owens P.C., Campbell R.G., Luxford B.G. Experimental correlations between insulin-like growth factors (IGFs) and growth rate show that endocrine IGF's are growth reporters, not drivers. Cranwell P.D. Manipulating Pig Production VI. 1997;171 Australian Pig Science Association, Werribee, Australia.
32. Luxford B.G., Bunter K.L., Owens P.C., Campbell R.G. Use of IGF-I as a selection criteria in pig breeding. Kratzmann S., Fearon P. Proceedings of the Pan Pacific Pork Expo. 1998;37-40 Australasian Pig Institute, Gatton, Australia.
33. Coleman M.E., Russell L., Etherton T.D. Porcine somatotropin (pST) increases IGF-I mRNA abundance in liver and subcutaneous (s.c.) adipose tissue but not in skeletal muscle of growing pigs. J Anim Sci. 72:1994;918-924.
34. Walton P.E., Dunshea F.R., Ballard F.J. In vivo actions of IGF analogues with poor affinities for IGFBPs Metabolic and growth effects in pigs of different ages and GH responsiveness . Proc Growth Fact Res. 6:1995;385-395.
35. Schoknecht P.A., Ebner S., Skottner A., Burrin D.G., Davis T.A., Ellis K., Pond W.G. Exogenous insulin-like growth factor-I increases weight gain in intrauterine growth-retarded neonatal pigs. Ped Res. 42:1997;201-207.
36. Fletcher T.P., Thomas G.B., Dunshea F.R., Moore L.G., Clarke I.J. IGF feedback effects on growth hormones secretion in ewes Evidence for action at the pituitary but not the hypothalamic level . J Endocrinol. 144:1995;323-331.
37. Tomas F.M., Knowles S.E., Chandler C.S., Francis G.L., Owens P.C., Ballard F.J. Anabolic effects of insulin-like growth factor-I (IGF-I) and an IGF-I variant in normal female rats. Endocrinology. 137:1993;413-421.
38. Elsaesser F., Granz S., Torronteras R. Ontogeny and control of growth hormone gene expression and secretion in the fetal pig. Reprod Domest Anim. 30:1995;163-169.