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Volumn 35, Issue 4, 1999, Pages 634-640

Amifostine (WR2721) for dose escalation in marrow-ablative treatment of leukaemia

Author keywords

Amifostine; Bone marrow transplantation; Dose escalation; Leukaemia

Indexed keywords

AMIFOSTINE; CYCLOPHOSPHAMIDE; MYELOABLATIVE AGENT;

EID: 0033118645     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(98)00412-2     Document Type: Article
Times cited : (8)

References (48)
  • 1
    • 0025128617 scopus 로고
    • Autologous bone marrow transplantation in acute myeloid leukemia in first remission: Results of a Dutch prospective study
    • Löwenberg B., Verdonck L.J., Dekker A., et al. Autologous bone marrow transplantation in acute myeloid leukemia in first remission: results of a Dutch prospective study. J. Clin. Oncol. 8:1990;287-294.
    • (1990) J. Clin. Oncol. , vol.8 , pp. 287-294
    • Löwenberg, B.1    Verdonck, L.J.2    Dekker, A.3
  • 2
    • 0025819698 scopus 로고
    • Impact of pretransplant conditioning and donor T-cells on chimerism, graft-versus-host disease, graft-versus-leukemia reactivity and tolerance after bone marrow transplantation
    • Truitt R.L., Atasoylu A.A. Impact of pretransplant conditioning and donor T-cells on chimerism, graft-versus-host disease, graft-versus-leukemia reactivity and tolerance after bone marrow transplantation. Blood. 77:1991;2515-2523.
    • (1991) Blood , vol.77 , pp. 2515-2523
    • Truitt, R.L.1    Atasoylu, A.A.2
  • 3
    • 0027471156 scopus 로고
    • Gene-marking to trace origin of relapse after autologous bone-marrow transplantation
    • Brenner M.K., Rill D.R., Moen R.C., et al. Gene-marking to trace origin of relapse after autologous bone-marrow transplantation. Lancet. 341:1993;85-86.
    • (1993) Lancet , vol.341 , pp. 85-86
    • Brenner, M.K.1    Rill, D.R.2    Moen, R.C.3
  • 4
    • 0028059252 scopus 로고
    • A review of the use of chemoprotectants in cancer chemotherapy
    • Lewis C. A review of the use of chemoprotectants in cancer chemotherapy. Drug Safety. 11:1994;153-162.
    • (1994) Drug Safety , vol.11 , pp. 153-162
    • Lewis, C.1
  • 6
    • 0025949836 scopus 로고
    • Protection against late effects of radiation by S-2[3-aminopropyl-amino]ethylphosphorothioic acid
    • Grdina D.J., Carnes Grahn D., Sigdestad C.P. Protection against late effects of radiation by S-2[3-aminopropyl-amino]ethylphosphorothioic acid. Cancer Res. 51:1991;4125-4130.
    • (1991) Cancer Res. , vol.51 , pp. 4125-4130
    • Grdina, D.J.1    Carnes Grahn, D.2    Sigdestad, C.P.3
  • 7
    • 0026670669 scopus 로고
    • Radiation-induced lymphoid tumors and radiation lethality are inhibited by combined treatment with small doses of zinc aspartate and WR 2721
    • Floersheim G.L., Christ A., Koenig R., Racine C., Gudat F. Radiation-induced lymphoid tumors and radiation lethality are inhibited by combined treatment with small doses of zinc aspartate and WR 2721. Int. J. Cancer. 52:1992;604-608.
    • (1992) Int. J. Cancer , vol.52 , pp. 604-608
    • Floersheim, G.L.1    Christ, A.2    Koenig, R.3    Racine, C.4    Gudat, F.5
  • 8
    • 0027083052 scopus 로고
    • Cytostatic activity of cisplatin in the presence of WR2721 and its thiol metabolite WR1065 in OVCAR-3 human ovarian cancer cells as compared to V79 fibroblasts
    • Treskes M., Nijtmans L., Fichtinger-Schepman A.M., van der Vijgh W.J. Cytostatic activity of cisplatin in the presence of WR2721 and its thiol metabolite WR1065 in OVCAR-3 human ovarian cancer cells as compared to V79 fibroblasts. Anticancer Res. 12:1992;2261-2265.
    • (1992) Anticancer Res. , vol.12 , pp. 2261-2265
    • Treskes, M.1    Nijtmans, L.2    Fichtinger-Schepman, A.M.3    Van der Vijgh, W.J.4
  • 9
    • 0028323126 scopus 로고
    • Effects of the modulating agent WR2721 on myelotoxicity and antitumour activity in carboplatin-treated mice
    • Treskes M., Boven E., van de Loosdrecht A.A., et al. Effects of the modulating agent WR2721 on myelotoxicity and antitumour activity in carboplatin-treated mice. Eur. J. Cancer. 30:1994;183-187.
    • (1994) Eur. J. Cancer , vol.30 , pp. 183-187
    • Treskes, M.1    Boven, E.2    Van de Loosdrecht, A.A.3
  • 10
    • 0027517584 scopus 로고
    • WR2721 as a modulator of cisplatin- and carboplatin-induced side effects in comparison with other chemoprotective agents: A molecular approach. [Review]
    • Treskes M., van der Vijgh W.J. WR2721 as a modulator of cisplatin- and carboplatin-induced side effects in comparison with other chemoprotective agents: a molecular approach. [Review]. Cancer Chemother. Pharmacol. 33:1993;93-106.
    • (1993) Cancer Chemother. Pharmacol. , vol.33 , pp. 93-106
    • Treskes, M.1    Van der Vijgh, W.J.2
  • 11
    • 0029091758 scopus 로고
    • A phase I trial of amifostine (WR-2721) and melphalan in children with refractory cancer
    • Adamson P.C., Balis F.M., Belasco J.E., et al. A phase I trial of amifostine (WR-2721) and melphalan in children with refractory cancer. Cancer Res. 55:1995;4069-4072.
    • (1995) Cancer Res. , vol.55 , pp. 4069-4072
    • Adamson, P.C.1    Balis, F.M.2    Belasco, J.E.3
  • 12
    • 0023815322 scopus 로고
    • Influence of WR2721 on DNA cross-linking by nitrogen mustard in normal mouse bone marrow and leukemia cells in vivo
    • DeNeve W.J., Everett C.K., Suminski J.E., Valeriote F.A. Influence of WR2721 on DNA cross-linking by nitrogen mustard in normal mouse bone marrow and leukemia cells in vivo. Cancer Res. 48:1988;6002-6005.
    • (1988) Cancer Res. , vol.48 , pp. 6002-6005
    • DeNeve, W.J.1    Everett, C.K.2    Suminski, J.E.3    Valeriote, F.A.4
  • 13
    • 0019466844 scopus 로고
    • Modification of tumor and host response to cyclophosphamide by misonidasole and by WR-2721
    • Twentyman P.R. Modification of tumor and host response to cyclophosphamide by misonidasole and by WR-2721. Br. J. Cancer. 43:1981;745-755.
    • (1981) Br. J. Cancer , vol.43 , pp. 745-755
    • Twentyman, P.R.1
  • 15
    • 0026056374 scopus 로고
    • Intraoperative radiotherapy with localized radioprotection: Diminished duodenal toxicity with intraluminal WR2721
    • Halberg F.E., LaRue S.M., Rayner A.A., et al. Intraoperative radiotherapy with localized radioprotection: diminished duodenal toxicity with intraluminal WR2721. Int. J. Radiat. Oncol. Biol. Phys. 21:1991;1241-1246.
    • (1991) Int. J. Radiat. Oncol. Biol. Phys. , vol.21 , pp. 1241-1246
    • Halberg, F.E.1    LaRue, S.M.2    Rayner, A.A.3
  • 16
    • 0027967713 scopus 로고
    • Radioprotection of the rat small intestines with topical WR-2721
    • Delaney J.P., Bonsack M.E., Felemovicius I. Radioprotection of the rat small intestines with topical WR-2721. Cancer. 74:1994;2379-2384.
    • (1994) Cancer , vol.74 , pp. 2379-2384
    • Delaney, J.P.1    Bonsack, M.E.2    Felemovicius, I.3
  • 17
    • 0026585459 scopus 로고
    • A neurologist's approach to neuroblastoma
    • Schor N.F. A neurologist's approach to neuroblastoma. J. Child. Neurol. 7:1992;93-98.
    • (1992) J. Child. Neurol. , vol.7 , pp. 93-98
    • Schor, N.F.1
  • 18
    • 0021806845 scopus 로고
    • Late functional and biochemical changes in mouse lung after irradiation. Differential effects of WR2721
    • Travis E.L., Meistrich M.L., Finch-Meimeyer M.V., Watkins T.L., Kiss I. Late functional and biochemical changes in mouse lung after irradiation. Differential effects of WR2721. Radiat. Res. 103:1985;219-231.
    • (1985) Radiat. Res. , vol.103 , pp. 219-231
    • Travis, E.L.1    Meistrich, M.L.2    Finch-Meimeyer, M.V.3    Watkins, T.L.4    Kiss, I.5
  • 19
    • 0025856595 scopus 로고
    • New protective agents for bone marrow in cancer therapy
    • McCulloch W., Scheffler B.J., Schein P.S. New protective agents for bone marrow in cancer therapy. Cancer Invest. 9:1991;279-287.
    • (1991) Cancer Invest. , vol.9 , pp. 279-287
    • McCulloch, W.1    Scheffler, B.J.2    Schein, P.S.3
  • 20
    • 0013549259 scopus 로고
    • Differential protection against alkylating agent injury in tumors and normal tissues.
    • In Nygaard OF, Simic MG, eds. New York, Academic Press
    • Phillips TL, Yuhas JM, Wasserman TH. Differential protection against alkylating agent injury in tumors and normal tissues. In Nygaard OF, Simic MG, eds. Radioprotectors and Anticarcinogens. New York, Academic Press, 1983, 735-748.
    • (1983) Radioprotectors and Anticarcinogens. , pp. 735-748
    • Phillips TL1    Yuhas JM2    Wasserman, TH.3
  • 21
    • 0027943634 scopus 로고
    • Radiotherapeutic studies with amifostine (Ethyol) [Review]
    • Wasserman T.H. Radiotherapeutic studies with amifostine (Ethyol) [Review]. Semin. Oncol. 21:1994;21-25.
    • (1994) Semin. Oncol. , vol.21 , pp. 21-25
    • Wasserman, T.H.1
  • 22
    • 0029080096 scopus 로고
    • Amifostine plus granulocyte colony-stimulating factor therapy enhances recovery from supralethal radiation exposures: Preclinical experience in animal models
    • Patchen M.L. Amifostine plus granulocyte colony-stimulating factor therapy enhances recovery from supralethal radiation exposures: preclinical experience in animal models. Eur. J. Cancer. 31A:(Suppl):1995;S17-S21.
    • (1995) Eur. J. Cancer , vol.31 , Issue.SUPPL.
    • Patchen, M.L.1
  • 24
    • 0024364159 scopus 로고
    • Purging of small cell lung cancer cells from human bone marrow using Ethiofos (WR-2721) and light activated Merocyanine 540 phototreatment
    • Meagher R.C., Rothman S.A., Paul P., Koberna P., Willmer C., Baucco P.A. Purging of small cell lung cancer cells from human bone marrow using Ethiofos (WR-2721) and light activated Merocyanine 540 phototreatment. Cancer Res. 49:1989;3637-3641.
    • (1989) Cancer Res. , vol.49 , pp. 3637-3641
    • Meagher, R.C.1    Rothman, S.A.2    Paul, P.3    Koberna, P.4    Willmer, C.5    Baucco, P.A.6
  • 25
    • 0028364704 scopus 로고
    • Amifostine (WR-2721) shortens the engraftment period of 4-hydroperoxycyclophosphamide-purged bone marrow in breast cancer patients receiving high-dose chemotherapy with autologous bone marrow support
    • Shpall E.J., Stemmer S.M., Hami L., et al. Amifostine (WR-2721) shortens the engraftment period of 4-hydroperoxycyclophosphamide-purged bone marrow in breast cancer patients receiving high-dose chemotherapy with autologous bone marrow support. Blood. 83:1994;3132-3137.
    • (1994) Blood , vol.83 , pp. 3132-3137
    • Shpall, E.J.1    Stemmer, S.M.2    Hami, L.3
  • 26
    • 0029124737 scopus 로고
    • Amifostine (WR2721) protects normal haemopoietic stem cells against cyclophosphamide derivatives' toxicity without compromising their antileukemic effects
    • Douay L., Hu C., Giarratana M-C., Gorin N-C. Amifostine (WR2721) protects normal haemopoietic stem cells against cyclophosphamide derivatives' toxicity without compromising their antileukemic effects. Eur. J. Cancer. 31A:(Suppl):1995;S14-S16.
    • (1995) Eur. J. Cancer , vol.31 , Issue.SUPPL.
    • Douay, L.1    Hu, C.2    Giarratana, M-C.3    Gorin, N-C.4
  • 27
    • 0029162994 scopus 로고
    • Amifostine improves the antileukemic therapeutic index of mafosfamide: Implications for bone marrow purging
    • Douay L., Hu C., Giarratana M.C., et al. Amifostine improves the antileukemic therapeutic index of mafosfamide: implications for bone marrow purging. Blood. 86:1995;2849-2855.
    • (1995) Blood , vol.86 , pp. 2849-2855
    • Douay, L.1    Hu, C.2    Giarratana, M.C.3
  • 28
    • 0029090540 scopus 로고
    • Protection of normal tissues from the cytotoxic effects of chemotherapy and radiation by amifostine (WR-2721): Preclinical aspects
    • Peters G.J., van der Vijgh W.J. Protection of normal tissues from the cytotoxic effects of chemotherapy and radiation by amifostine (WR-2721): preclinical aspects. Eur. J. Cancer. 31A:(Suppl: S):1994;1-7.
    • (1994) Eur. J. Cancer , vol.31 A , Issue.SUPPL S , pp. 1-7
    • Peters, G.J.1    Van der Vijgh, W.J.2
  • 29
    • 0021914053 scopus 로고
    • Alkaline phosphatase promotes radioprotection and accumulation of WRA-1065 in V79-171 cells incubated in medium containing WR2721
    • Calabro-Jones P.M., Fahey R.C., Smoluk G.D., Ward J.F. Alkaline phosphatase promotes radioprotection and accumulation of WRA-1065 in V79-171 cells incubated in medium containing WR2721. Int. J. Radiat. Biol. 47:1985;23-27.
    • (1985) Int. J. Radiat. Biol. , vol.47 , pp. 23-27
    • Calabro-Jones, P.M.1    Fahey, R.C.2    Smoluk, G.D.3    Ward, J.F.4
  • 30
    • 0026716746 scopus 로고
    • The current status of toxicity protectants in cancer therapy
    • Schuchter L.M., Luginbuhl W.E., Meropol N.J. The current status of toxicity protectants in cancer therapy. Semin Oncol. 19:1992;742-751.
    • (1992) Semin Oncol , vol.19 , pp. 742-751
    • Schuchter, L.M.1    Luginbuhl, W.E.2    Meropol, N.J.3
  • 31
    • 0019119832 scopus 로고
    • Treatment of tumors with the combination of WR-2721 and cis-dicholordiammineplatinum (II) or cyclophosphamide
    • Yuhas J.M., Spellman J.M., Jordan S.W., Pardini M.C., Afzal S.M.H., Culo F. Treatment of tumors with the combination of WR-2721 and cis-dicholordiammineplatinum (II) or cyclophosphamide. Br. J. Cancer. 42:1980;574-585.
    • (1980) Br. J. Cancer , vol.42 , pp. 574-585
    • Yuhas, J.M.1    Spellman, J.M.2    Jordan, S.W.3    Pardini, M.C.4    Afzal, S.M.H.5    Culo, F.6
  • 32
    • 0022479445 scopus 로고
    • Potentiation of nitrogen mustard cytotoxicity to leukemia cells by sulfur-containing compounds administered in vivo
    • Valeriote F., Grates H.E. Potentiation of nitrogen mustard cytotoxicity to leukemia cells by sulfur-containing compounds administered in vivo. Int. J. Radiat. Oncol. Biol. Phys. 12:1986;1165-1169.
    • (1986) Int. J. Radiat. Oncol. Biol. Phys. , vol.12 , pp. 1165-1169
    • Valeriote, F.1    Grates, H.E.2
  • 33
    • 0025248059 scopus 로고
    • The BN acute myelocytic leukemia model. A model for studying human acute myelocytic leukemia (AML)
    • Martens A.C.M., van Bekkum D.W., Hagenbeek A. The BN acute myelocytic leukemia model. A model for studying human acute myelocytic leukemia (AML). Leukaemia. 4:1990;241-257.
    • (1990) Leukaemia , vol.4 , pp. 241-257
    • Martens, A.C.M.1    Van Bekkum, D.W.2    Hagenbeek, A.3
  • 34
    • 0019951693 scopus 로고
    • High dose cyclophosphamide treatment of acute myelocytic leukemia. Studies in the BNML rat model
    • Hagenbeek A., Martens A.C.M. High dose cyclophosphamide treatment of acute myelocytic leukemia. Studies in the BNML rat model. Eur. J. Cancer Clin. Oncol. 18:1982;763-769.
    • (1982) Eur. J. Cancer Clin. Oncol. , vol.18 , pp. 763-769
    • Hagenbeek, A.1    Martens, A.C.M.2
  • 35
    • 0020698235 scopus 로고
    • The efficacy of high dose cyclophosphamide in combination with total body irradiation in the treatment of acute myelocytic leukemia. Studies in a relevant rat model (BNML)
    • Hagenbeek A., Martens A.C.M. The efficacy of high dose cyclophosphamide in combination with total body irradiation in the treatment of acute myelocytic leukemia. Studies in a relevant rat model (BNML). Cancer Res. 43:1983;408-412.
    • (1983) Cancer Res. , vol.43 , pp. 408-412
    • Hagenbeek, A.1    Martens, A.C.M.2
  • 38
    • 0013548911 scopus 로고    scopus 로고
    • StatView.
    • Berkeley, California, U.S.A.
    • StatView. Abacus Concepts, Berkeley, California, U.S.A.
    • Abacus Concepts
  • 39
    • 0025734611 scopus 로고
    • Minimal residual disease in acute leukaemia: preclinical studies in a relevant rat leukaemia model (BNML).
    • In Proctor SJ, ed.
    • Hagenbeek A, Martens ACM. Minimal residual disease in acute leukaemia: preclinical studies in a relevant rat leukaemia model (BNML). In Proctor SJ, ed. Bailliére's Clinical Haematology, Vol. 4, No. 3, 1991, 609-635.
    • (1991) Bailliére's Clinical Haematology , vol.4 , Issue.3 , pp. 609-635
    • Hagenbeek A1    Martens, ACM.2
  • 40
    • 0019424730 scopus 로고
    • Differential protection against cytotoxic chemotherapeutic effects on bone marrow CFU-S by WR2721
    • Wasserman T.H., Phillips T.L., Ross G., Kane L.J. Differential protection against cytotoxic chemotherapeutic effects on bone marrow CFU-S by WR2721. Cancer Clin. Trials. 4:1981;3-6.
    • (1981) Cancer Clin. Trials , vol.4 , pp. 3-6
    • Wasserman, T.H.1    Phillips, T.L.2    Ross, G.3    Kane, L.J.4
  • 41
    • 0031427376 scopus 로고    scopus 로고
    • Amifostine protects normal tissues from paclitaxel toxicity while cytotoxicity against tumour cells is maintained
    • Taylor C.W., Wang L.M., List A.F., et al. Amifostine protects normal tissues from paclitaxel toxicity while cytotoxicity against tumour cells is maintained. Eur. J. Cancer. 33:1997;1693-1698.
    • (1997) Eur. J. Cancer , vol.33 , pp. 1693-1698
    • Taylor, C.W.1    Wang, L.M.2    List, A.F.3
  • 42
    • 0030735082 scopus 로고    scopus 로고
    • Stimulation of hematopoiesis by amifostine in patients with myelodysplastic syndrome
    • List A.F., Brasfield R., Heaton R., et al. Stimulation of hematopoiesis by amifostine in patients with myelodysplastic syndrome. Blood. 90:1997;3364-3369.
    • (1997) Blood , vol.90 , pp. 3364-3369
    • List, A.F.1    Brasfield, R.2    Heaton, R.3
  • 43
    • 0024990851 scopus 로고
    • Separation of pluripotent hematopoietic stem cells from spleen colony forming cells
    • Jones R.J., Wagner J.E., Celano P., Zicha M.S., Sharkis S.J. Separation of pluripotent hematopoietic stem cells from spleen colony forming cells. Nature. 347:1990;188.
    • (1990) Nature , vol.347 , pp. 188
    • Jones, R.J.1    Wagner, J.E.2    Celano, P.3    Zicha, M.S.4    Sharkis, S.J.5
  • 44
    • 0025003356 scopus 로고
    • Marrow repopulating cells but not CFU-S establish long term in vitro hematopoiesis on a marrow derived stromal layer
    • Van der Sluijs J.P., De Jong J.P., Brons N.H.C., Ploemacher R.E. Marrow repopulating cells but not CFU-S establish long term in vitro hematopoiesis on a marrow derived stromal layer. Exp. Hematol. 18:1990;893.
    • (1990) Exp. Hematol. , vol.18 , pp. 893
    • Van der Sluijs, J.P.1    De Jong, J.P.2    Brons, N.H.C.3    Ploemacher, R.E.4
  • 45
    • 0028358913 scopus 로고
    • Frequency analysis of human primitive haematopoietic subsets using a cobblestone area forming cell assay
    • Breems D.A., Blokland E.A.W., Neben S., Ploemacher R.E. Frequency analysis of human primitive haematopoietic subsets using a cobblestone area forming cell assay. Leukemia. 8:1994;1095-1104.
    • (1994) Leukemia , vol.8 , pp. 1095-1104
    • Breems, D.A.1    Blokland, E.A.W.2    Neben, S.3    Ploemacher, R.E.4
  • 47
    • 0031055257 scopus 로고    scopus 로고
    • Effects of amifostine (WR-2721, ethyol) on tumor growth and pharmacology of cytotoxic drugs in human xenotransplanted neuroblastomas
    • Fichtner I., Lemm M., Becker M., Berthold F. Effects of amifostine (WR-2721, ethyol) on tumor growth and pharmacology of cytotoxic drugs in human xenotransplanted neuroblastomas. Anticancer Drugs. 8:1997;174-181.
    • (1997) Anticancer Drugs , vol.8 , pp. 174-181
    • Fichtner, I.1    Lemm, M.2    Becker, M.3    Berthold, F.4
  • 48
    • 0030789852 scopus 로고    scopus 로고
    • Bone marrow protection with amifostine in the treatment of high-risk malignant lymphoma
    • Aviles A., Diaz M.J., Talavera A., Garcia E.L., Guzman R., Nambo M.J. Bone marrow protection with amifostine in the treatment of high-risk malignant lymphoma. Eur. J. Cancer. 33:1997;1323-1325.
    • (1997) Eur. J. Cancer , vol.33 , pp. 1323-1325
    • Aviles, A.1    Diaz, M.J.2    Talavera, A.3    Garcia, E.L.4    Guzman, R.5    Nambo, M.J.6


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