Enantioselective synthesis of β-amino acid via asymmetric bromolactamization

Heterocycles

Volumn 50, Issue 2, 1999, Pages 677-680

  Jew, Sang Sup ^a   Cha, Kyung Hoi ^a   Kang, Sang Deog ^a   Woo, Yun Hee ^a   Kim, Hyung Ook ^a   Park, Hyeung Geun ^a  

^a Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; BETA AMINO ACID; BUTYRIC ACID; LACTAM; PYRROLIDINE DERIVATIVE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; ENANTIOMER; STEREOCHEMISTRY; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

EID: 0033117379     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-98-S(H)109     Document Type: Article

References (18)

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16. By careful analysis, we found that the six membered bromolactam was formed in 27% yield in this reaction.
17. 1; a = 6.0096 (0.1664) Å, b = 12.5852 (0.0795) Å, c = 17.0938 (0.0585) Å; R = 0.059.
18. 1H NMR, it was diastereomerically pure.