Atherosclerosis of the ascending aorta is an independent predictor of long-term neurologic events and mortality

Journal of the American College of Cardiology

Volumn 33, Issue 5, 1999, Pages 1308-1316

  Dávila Román, Victor G ^a,b   Murphy, Suzan F ^b   Nickerson, Nancy J ^c   Kouchoukos, Nicholas T ^d   Schechtman, Kenneth B ^a   Barzilai, Benico ^c  

^a Department of Biostatistics ^*

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MISSOURI BAPTIST MEDICAL CENTER   (United States)

^d WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AORTA ATHEROSCLEROSIS; ARTICLE; DIABETES MELLITUS; FEMALE; FOLLOW UP; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; STROKE;

AGED; AGED, 80 AND OVER; AORTA; AORTIC DISEASES; ARTERIOSCLEROSIS; BRAIN; CAROTID STENOSIS; CEREBROVASCULAR DISORDERS; FEMALE; FOLLOW-UP STUDIES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; SURVIVAL RATE; TOMOGRAPHY, X-RAY COMPUTED; ULTRASONOGRAPHY, DOPPLER, DUPLEX; VASCULAR SURGICAL PROCEDURES;

EID: 0033117118     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(99)00034-0     Document Type: Article

References (60)

1. Sirna S, Biller J, Skorton DJ, Seabold JE. Cardiac evaluation of the patient with stroke. Stroke 1990;21:14-23.
2. Keating EC, Gross SA, Schlamowitz RA, et al. Mural thrombi in myocardial infarctions: Prospective evaluation by two-dimensional echocardiography. Am J Med 1983;74:989-95.
3. Greenland P, Knopman DS, Mikell FL, et al. Echocardiography in diagnostic assessment of stroke. Ann Intern Med 1981;95:51-3.
4. Adams PC, Cohen M, Chesebro JH, Fuster V. Thrombosis and embolism from cardiac chambers and infected valves. J Am Coll Cardiol 1986;8:(Suppl B)76B-87B.
5. Pop G, Sutherland GR, Koudstaal PJ, et al. Transesophageal echocardiography in the detection of intracardiac embolic sources in patients with transient ischemic attacks. Stroke 1990;21:560-5.
6. Wolf PA, Dawber TR, Thomas HE, Kannel WB. Epidemiologic assessment of chronic atrial fibrillation and risk of stroke: The Framingham study. Neurology 1978;28:973-7.
7. Wolf PA, Kannel WB, McGee DL, et al. Duration of atrial fibrillation and imminence of stroke: The Framingham study. Stroke 1983;14:664-7.
8. Benjamin EJ, Plehn JF, D'Agostino RB, et al. Mitral annular calcification and the risk of stroke in an elderly cohort. N Engl J Med 1992;327:374-9.
9. Barnett HJM, Jones MW, Boughner DR, Kostuk WJ. Cerebral ischemic events associated with prolapsing mitral valve. Arch Neurol 1976;33:777-82.
10. Daniel WG, Nellessen U, Schroder E, et al. Left atrial spontaneous echo contrast in mitral valve disease: an indicator for an increased thromboembolic risk. J Am Coll Cardiol 1988;11:1204-11.
11. North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med 1991;325:445-53.
12. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. Endarterectomy for asymptomatic carotid artery stenosis. JAMA 1995;273:1421-8.
13. Sacco RL, Ellenberg JH, Mohr JP, et al. Infarcts of undetermined cause: The NINCDS Stroke Data Bank. Ann Neurol 1989;25:382-90.
14. Winter WJ. Atheromatous emboli; a cause of cerebral infarction. Arch Pathol 1957;64:137-42.
15. Sturgill BC, Netsky MG. Cerebral infarction by atheromatous emboli. Arch Neurol 1963;76:185-96.
16. Soloway HB, Aronson SM. Atheromatous emboli to central nervous system. Arch Pathol 1964;11:657-67.
17. Beal MF, Williams RS, Richardson EP Jr, Fisher CM. Cholesterol embolism as a cause of transient ischemic attacks and cerebral infarction. Neurology 1981;31:860-5.
18. Flory CM. Arterial occlusions produced by emboli from eroded aortic atheromatous plaques. Am J Pathol 1945;21:549-58.
19. Hoye SJ, Teitelbaum S, Gore I, Warren R. Atheromatous embolization: a factor in peripheral gangrene. N Engl J Med 1959;261:128-31.
20. Gore I, Collins DP. Spontaneous atheromatous embolization: review of the literature and report of 16 additional cases. Am J Clin Pathol 1960;33:416-26.
21. Dávila-Román VG, Barzilai B, Wareing TH, et al. Intraoperative ultrasonographic evaluation of the ascending aorta in 100 consecutive patients undergoing cardiac surgery. Circulation 1991;84(Suppl III):47-53.
22. Hosoda Y, Watanabe M, Hirooka Y, et al. Significance of atherosclerotic changes of the ascending aorta during coronary bypass surgery with intraoperative detection by echography. J Cardiovasc Surg 1991;32:301-6.
23. Ohteki H, Itoh T, Natsuaki M, et al. Intraoperative ultrasonic imaging of the ascending aorta in ischemic heart disease. Ann Thorac Surg 1990;50:539-42.
24. Wareing TH, Dávila-Román VG, Barzilai B, et al. Management of the severely atherosclerotic ascending aorta during cardiac operations. J Thorac Cardiovasc Surg 1992;103:453-62.
25. Wareing TH, Dávila-Román VG, Daily BB, et al. Strategy for the prevention of stroke in cardiac surgical patients. Ann Thorac Surg 1993;55:1400-7.
26. Dávila-Román VG, Barzilai B, Wareing TH, et al. Atherosclerosis of the ascending aorta: Prevalence and role as an independent predictor of cerebrovascular events in cardiac patients. Stroke 1994;25:2010-6.
27. Dávila-Román VG, Schechtman KB, Kouchoukos NT, Barzilai B. Atherosclerosis of the ascending aorta is a predictor of renal dysfunction after cardiac operations. J Thorac Cardiovasc Surg 1999;117:111-6.
28. Amarenco P, Duyckaerts C, Tzourio C, et al. The prevalence of ulcerated plaques in the aortic arch in patients with stroke. N Engl J Med 1992;362:221-5.
29. Tunick PA, Perez JL, Kronzon I. Protruding atheromas in the thoracic aorta and systemic embolization. Ann Intern Med 1991;115:423-7.
30. Karalis DG, Krishnaswamy C, Victor MF, et al. Recognition and embolic potential of intraaortic atherosclerotic debris. J Am Coll Cardiol 1991;17:73-8.
31. Rubin DC, Plotnick GD, Hawke MW. Intraaortic debris as a potential source of embolic stroke. Am J Cardiol 1992;15:819-20.
32. Dávila-Román VG, Westerhausen D, Hopkins WE, et al. Transesophageal echocardiography in the detection of cardiovascular sources of peripheral vascular embolism. Ann Vasc Surg 1995;9:252-60.
33. Tunick PA, Rosenzweig BP, Katz ES, et al. High risk for vascular events in patients with protruding aortic atheromas: a prospective study. J Am Coll Cardiol 1994;23:1085-90.
34. The French Study of aortic plaques in stroke group. Atherosclerotic disease of the aortic arch as a risk factor for recurrent ischemic stroke. N Engl J Med 1996;334:1216-21.
35. Mitusch R, Doherty C, Wucherpfenning H, et al. Vascular events during follow-up in patients with arch atherosclerosis. Stroke 1997;28:36-9.
36. Hartman GS, Yao F-S F, Bruefach M, et al. Severity of aortic atheromatous disease diagnosed by transesophageal echocardiography predicts stroke and other outcomes associated with coronary artery surgery: a prospective study. Anesth Analg 1996;83:701-8.
37. Kennedy JW, Kaiser GC, Fisher LD, et al. Clinical and angiographic predictors of operative mortality from the collaborative Study in Coronary Artery Surgery (CASS). Circulation 1981;63:793-802.
38. Dávila-Román VG, Phillips KJ, Daily BB, et al. Intraoperative transesophageal echocardiography and epiaortic ultrasound for assessment of atherosclerosis of the thoracic aorta. J Am Coll Cardiol 1996;28:942-7.
39. Berens ES, Kouchoukos NT, Murphy SF, Wareing TH. Preoperative carotid artery screening in elderly patients undergoing cardiac surgery. J Vasc Surg 1992;15:313-27.
40. Steinke W, Kloetzsch C, Hennerici M. Carotid artery disease assessed by color Doppler flow imaging: Correlation with standard Doppler sonography and angiography. Am J Radiol 1990;154:1061-8.
41. Kannel WB, Wolf PA, Verter J, McNamara PM. Epidemiologic assessment of the role of blood pressure in stroke. The Framingham Study. JAMA 1970;214:301-10.
42. Whisnant JP. Epidemiology of stroke: emphasis on transient cerebral ischemic attacks and hypertension. Stroke 1974;5:68-70.
43. MacMahon S, Rodgers A. Blood pressure, antihypertensive treatment and stroke risk. J Hypertens 1994(Suppl);12:5-14.
44. Collins R, Peto R, MacMahon S, et al. Blood pressure, stroke, and coronary heart disease, part 2: Short-term reductions in blood pressure. Overview of randomised drug trials in their epidemiological context. Lancet 1990;335:827-38.
45. SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA 1991;265:3255-64.
46. Weinberger J, Biscarra V, Weisberg MK, Jacobson JH. Factors contributing to stroke in patients with atherosclerotic disease of the great vessels: the role of diabetes. Stroke 1983;14:709-12.
47. Kjell A, Erik H, Claes H, et al. The natural history of stroke in diabetic patients. Acta Med Scand 1980;207:417-24.
48. Helgason CM. Blood glucose and stroke. Stroke. 1988;18:1049-53.
49. Moldveen-Geronimus M, Merriam JC Jr. Cholesterol embolization: from pathological curiosity to clinical entity. Circulation 1967;35:946-53.
50. Smith MC, Ghose MK, Henry AR. The clinical spectrum of renal cholesterol embolization. Am J Med 1981;71:174-80.
51. Feder W, Auerbach R. "Purple toes": an uncommon sequela of oral coumarin drug therapy. Ann Intern Med 1961;55:913-7.
52. Bruns FJ, Segel DP, Adler S. Control of cholesterol embolization by discontinuation of anticoagulant therapy. Am J Med Sci 1978;275:105-8.
53. Blauth CI, Cosgrove DM, Webb BW, et al. Atheroembolism from the ascending aorta: an emerging problem in cardiac surgery. J Thorac Cardiovasc Surg 1992;103:1104-12.
54. Harrington JT, Sommers SC, Kassirer JP. Atheromatous emboli with progressive renal failure: renal arteriography as the probable inciting factor. Ann Intern Med 1968;68:152-60.
55. Konstadt SN, Reich DL, Quintana C, Levy M. The Ascending Aorta: How Much Does Transesophageal Echocardiography See? Anesth Analg 1994;78:240-4.
56. Laupacis A, Albers G, Dalen J, et al. Antithrombotic therapy in atrial fibrillation. Chest 1995;(Suppl)108:352-9.
57. Rokey R, Rolak LA, Harati Y, et al. Coronary artery disease in patients with cerebrovascular disease: a prospective study. Ann Neurol 1984;16:50-3.
58. Kannel WB, Wolf PA, Verter J. Manifestations of coronary disease predisposing to stroke. The Framingham study. JAMA 1983;250:2942-6.
59. Dressler FA, Craig WR, Castello R, Labovitz AJ. Mobile aortic atheroma and systemic emboli: efficacy of anticoagulation and influence of plaque morphology on recurrent stroke. J Am Coll Cardiol 1998;31:134-8.
60. Fisher M, Jones S, Sacco RL. Prophylactic neuroprotection for cerebral ischemia. Stroke 1994;25:1075-80.