Therapeutic strategy for post-transfusion graft-vs.-host disease

International Journal of Hematology

Volumn 69, Issue 3, 1999, Pages 147-151

  Saigo, Katsuyasu ^a   Ryo, Ryukichi ^b  

^a KOBE UNIVERSITY HOSPITAL   (Japan)

^b KOBE UNIVERSITY   (Japan)

Author keywords

Adenosine deaminase inhibitor; Granzyme; Post transfusion graft vs. host disease; Serine protease inhibitor; Tumor necrosis factor

Indexed keywords

ANTIRHEUMATIC AGENT; CHLOROQUINE; ENZYME INHIBITOR; LIGAND; PENTOXIFYLLINE; TUMOR NECROSIS FACTOR ALPHA;

BLOOD TRANSFUSION; DRUG EFFECT; GRAFT VERSUS HOST REACTION; HUMAN; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; REVIEW; T LYMPHOCYTE;

ANTIRHEUMATIC AGENTS; BLOOD TRANSFUSION; CHLOROQUINE; ENZYME INHIBITORS; GRAFT VS HOST DISEASE; HUMANS; IMMUNOSUPPRESSION; LIGANDS; PENTOXIFYLLINE; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033108804     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Mori S, Matsushita H, Ozaki K, et al. Spontaneous resolution of transfusion-associated graft-versus-host disease. Transfusion 1995;35:431-5.
2. Friedman DF, Kwittken P, Cizman B, et al. DNA-based HLA typing of nonhematopoietic tissue used to select the marrow transplant donor for successful treatment of transfusion-associated graft-versus-host disease. Clin Diag Lab Immunol 1994;1:590-6.
3. Yasukawa M, Shinozaki F, Hato T, et al. Successful treatment of transfusion-associated graft-versus-host disease. Brit J Haematol 1994;86:831-6.
4. Yahagi H, Uchida S, Takahashi M, et al. Recovery of patient peripheral blood mononuclear cells after treatment with protease inhibitor in post-transfusion graft-versus- host disease. Proc Japan Acad 1997;73:79-84.
5. Ryo R, Saigo K, Hashimoto M, et al. Treatment of post-transfusion graft-versus-host disease with a serine protease inihibitor: A case report. Vox Sang (in press).
6. Nishimura M, Uchida S, Mitsunaga S, et al. Characterization of T-cell clones derived from peripheral blood lymphocytes of a patient with transfusion-associated graft-versus-host disease: Fas-mediated killing by CD4+ and CD8+ cytotoxic T-cell clones and tumor necrosis factor β production by CD4+ T-cell clones. Blood 1997;151:1440-5.
7. Epstein JLM, Deeg HJ. Graft-versus-host-disease. N Eng J Med 1991;324:667-74.
8. Nishimura M, Akaza T, Tadokoro K, Juji T. Potential usefulness of protease inhibitor and chloroquine in the treatment of transfusion-associated graft-versus-host disease. Transfusion 1997;37:768-70.
9. Shi L, Kam CM, Powers JC, Aebersold R, Greenberg AH. Purification of three cytotoxic lymphocytes granule serine proteases that induce apoptosis through distinct substrate and target cell interactions. J Exp Med 1992;176:1521-9.
10. Liu CC, Young LHY, Young JDE. Lymphocyte-mediated cytolysis and disease. New Eng J Med 1996;335:1651-9.
11. Liu CC, Rafii S, Granelli-Piperno A, Trapani JA, Young JDE. Perforin and serine protease gene expression in stimulated human T cells. Kinetics, mitogen requirements and effects of cyclosporin A. J Exp Med 1989;170:2105-18.
12. Darmon AJ, Nicholson DW, Bleackley RC. Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. Nature 1995;377:446-8.
13. Lipman ML, Stevens C, Bleackley C, et al. The strong correlation of cytotoxic T lymphocyte-specific serine protease gene transcriptions with renal allograft rejection. Transplantation 1992;53:73-9.
14. Heusel JW, Wesselschmidt RL, Shresta S, Russell JH, Ley TJ. Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell 1994;76:977-87.
15. Nishimura M, Uchida S, Mitsunaga S, Tokunaga K, Tadokoro K, Juji T. Evidence of involvement of cytotoxic antibodies directed against patient's HLA class II produced by transfused donorderived B cells in post-transfusion graft-versus-host disease. Brit J Haematol 1996;92:1011-13.
16. Wang L, Juji T, Tokunaga K, et al. Polymorphic microsatellite markers for the diagnosis of graft-versus-host disease. N Eng J Med 1994;330:398-401.
17. Ryo R, Hashimoto M, Fujioka T, Saigo K. Early diagnosis of post-transfusion graft-versus-host disease. Bull Allied Med Sci Kobe (in press).
18. Norton J, Sloane JP. ICAM-1 expression on epidermal keratinocytes in cutaneous graft-versus-host disease. Transplantation 1991;51:1203-6.
19. Antin JH, Ferrara JLM. Cytokine dysregulation and acute graft-versus-disease. Blood 1992;80:2964-8.
20. Herv P, Flesch M. Tiberghien P, et al. Phase I-II trial of a monoclonal anti-tumor necrosis factor α antibody for the treatment of refractory severe acute graft-versus-host disease. Blood 1992;79:3362-8.
21. Kalden-Nemeth D, Grebmeier J, Antoni C, Manger B, Wolf F, Kalden JR. NMR monitoring of rheumatoid arthritis patients receiving anti-TNF-alpha monoclonal antibody therapy. Rheumatol Int 1997;16:249-55.
22. Targan SR, Hanauer SB, van Deventer SJH, et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor a for Crohn's disease. N Eng J Med 1997;337:1029-35.