Skin perfusion responses to surface pressure-induced ischemia: Implication for the developing pressure ulcer

Journal of Rehabilitation Research and Development

Volumn 36, Issue 2, 1999, Pages 109-120

  Herrman, Eric C ^a   Knapp, Charles F ^a   Donofrio, James C ^a,b   Salcido, Richard ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Animal model; Decubitus; Ischemia reperfusion; Pressure ulcer; Skin perfusion; Surface pressure

Indexed keywords

FLOW MEASUREMENT; HEMODYNAMICS; LASER DOPPLER VELOCIMETERS; PRESSURE EFFECTS; SKIN; TEMPERATURE MEASUREMENT; THERMISTORS;

PRESSURE ULCER; SKIN PERFUSION;

PATIENT REHABILITATION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DECUBITUS; HEMOPERFUSION; HYPEREMIA; ISCHEMIA; MALE; NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; RAT; REPERFUSION INJURY; SKIN TEMPERATURE; SKIN ULCER; VASODILATATION;

ANIMALS; CELL SURVIVAL; ISCHEMIA; MALE; PRESSURE ULCER; RATS; REGIONAL BLOOD FLOW; SKIN; VASODILATION;

EID: 0033108772     PISSN: 07487711     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. National Pressure Ulcer Advisory Panel. Pressure ulcers prevalence, cost and risk assessment: consensus development conference statement. Decubitus 1989;2:24-8.
2. Allman RM. Pressure sores among the elderly. New Eng J Med 1989;320:850-3.
3. Schubert V, Fagrell B. Local skin pressure and its effects on skin microcirculation as evaluated by laser-Doppler fluxmetry. Clin Physiol 1989;9:535-45.
4. Salcido R, Fisher SB, Donofrio JC, et al. An animal model and computer-controlled surface pressure delivery system for the production of pressure ulcers. J Rehabil Res Dev 1995;32(2):149-61.
5. Bergstrom N. A research agenda for pressure ulcer prevention. Decubitus 1992;5:22-30.
6. Colantuoni A, Bertuglia S, Intaglietta M. Microvascular vasomotion: origin of laser Doppler flux motion. Int J Microcirc 1994;14:151-8.
7. Agache PG, Dupond AS. Recent advances in non-invasive assessment of human skin blood flow. Acta Derm Venereol (Stockh) 1994;185:47-51.
8. Stacy DL, Joyner WL, Gilmore JP. Arteriolar reactivity to pressure stimuli in hamsters with renal hypertension. Hypertension 1987;10(1):82-92.
9. Wamsley D, Wiles PG. Reactive hyperemia in skin of the human foot using laser doppler flowmeter: effects of duration of ischemia and local heating. Int J Microcirc 1990;9:345-55.
10. Ring EFJ. Thermal imaging of skin temperature. In: Serup J, Jemec G, editors. Handbook of non-invasive methods and the skin. Boca Raton, FL: CRC Press, Inc.; 1995. p. 457-71.
11. Russ GH, Motta GH. Eliminating pressure: is less than 32 mmHg enough for wound healing? Ostomy Wound Manage 1991;34:60-3.
12. Myers ER, Armstrong CG, Mow VC. Swelling pressure and collagen tension. In: Hukins DWL, editor. Connective tissue matrix. London: Macmillan; 1986. p. 161-79.
13. Jochmann W, Mostbeck A, Partsch H. Postocclusive reactive hyperemia and postural vasoconstriction in different kinds of leg ulcers. Vasa 1993;22(4):306-15.
14. Sack FU, Funk W, Hammersen F, Messmer K. Microvascular injury in skeletal muscle and skin after different periods of pressure induced ischemia. In: Progress in Applied Microcirculation. Vol 12. Basel: S. Karger, AG; 1987. p. 282-8.
15. Baker CH, Sutton ET. Antagonism of acetylcholine and adenosine rat cremaster arteriolar vasodilation by combination of NO antagonists. Int J Microcirc: Clin Exp 1993;12:275-86.
16. Tur E, Politi Y, Rubinstein A. Cutaneous blood flow abnormalities in hypertriglyceridema. J Invest Dermatol 1994;103:(4)597-600.
17. Giraldez RR, Panda A, Xia Y, Sanders SP, Zweier JL. Decreased nitric-oxide Systhase activity causes impaired endothelium-dependent relaxation in the postischemic heart. J Biol Chem 1997;272:21240-6.
18. Gidlof A, Lewis DH, Hammersen F. The effect of prolonged total ischemia on the ultrastructure of human skeletal muscle capillaries: a morphometric analysis. Int J Microcirc: Clin Exp 1988;7:67-86.
19. Hansell P, Borgstrum P, Arfors K-E. Pressure-related capillary leukostasis following ischemia-reperfusion and hemorrhagic shock. Am J Physiol 1993;265 (Heart Circ Physiol 34):H381-8.
20. Rochester JR, Brown NJ, Reed MWR. Reperfusion of chronically ischemic skeletal muscle increases local white cell adhesion (abstract). Int J Microcirc 1995;15:202.
21. Park JB, Lakes RS. Tissue response to implants. In: Park JB, editor. Biomaterials: an introduction. 2nd ed. New York: Plenum Press; 1992. p. 223-44.
22. Schubert V, Fagrell B. Evaluation of the dynamic cutaneous post-ischemic hyperemia and thermal response in elderly subjects and in an area at risk for pressure sores. Clin Physiol 1991;11:169-82.
23. Hashimoto H. Impaired microvascular vasodilator reserve in chronic cigarette smokers: a study of postocclusive reactive hyperemia in the human finger. Jpn Circ J 1994;58:29-33.
24. Carlsson I, Sollevi A, Wennalm A. The role of myogenic relaxation, adenosine and prostaglandins in human forearm reactive hyperemia. J Physiol 1987;389:147-61.
25. Patel SS. Effects of temperature on surface pressure induced changes in perfusion (dissertation). Lexington, KY: University of Kentucky; 1996.
26. Sanada H, Nagakawa T, Yamamoto M, Higashidani K, Tsuru H, Sugama J. The role of skin blood flow in pressure ulcer development during surgery. Adv Wound Care 1997;10:29-34.