Confronting Misconduct in Science in the 1980s and 1990s: What has and has not been accomplished?

Science and Engineering Ethics

Volumn 5, Issue 2, 1999, Pages 161-176

  Steneck, Nicholas H ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Ethics; Integrity; Misconduct; Policy; Research; Science

Indexed keywords

ARTICLE; BIOMEDICAL AND BEHAVIORAL RESEARCH; GOVERNMENT; GOVERNMENT REGULATION; HUMAN; LEGAL APPROACH; MEDICAL ETHICS; MEDICAL RESEARCH; PEER REVIEW; POLICY; RESEARCH; SCIENTIFIC MISCONDUCT; SOCIAL CHANGE; SOCIAL CONTROL; STATISTICS; UNITED STATES; UNIVERSITY;

BIOMEDICAL AND BEHAVIORAL RESEARCH; LEGAL APPROACH;

BIOMEDICAL RESEARCH; ETHICS, PROFESSIONAL; FEDERAL GOVERNMENT; GOVERNMENT; GOVERNMENT REGULATION; HUMANS; ORGANIZATIONAL POLICY; PEER REVIEW; RESEARCH; SCIENTIFIC MISCONDUCT; SOCIAL CHANGE; SOCIAL CONTROL, FORMAL; SOCIAL CONTROL, INFORMAL; STATISTICS; UNITED STATES; UNIVERSITIES;

EID: 0033107965     PISSN: 13533452     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11948-999-0005-x     Document Type: Article

References (100)

1. U.S. Congress, House. Committee on Science and Technology. Subcommittee on Investigations and Oversight (1981) Fraud in biomedical research. GPO, Washington, DC.
2. U.S. Congress (1985) Health Research Extension Act of 1985. GPO, Washington, DC.
3. Broad, W.J. and Wade, N. (1982) Betrayers of the truth: Fraud and deceit in the halls of science. Simon and Schuster, New York.
4. Hilts, P.J. (1981) Science confronted with "crime waves" of researchers faking data in experiments. Los Angeles Times (March 4): 6.
5. Broad, W.J. (1981) Fraud and the structure of science. Science 212 (April 10): 37.
6. Broad, W.J. and Wade, N. (1982) Science's faulty fraud detectors. Psychology Today 16 (November): 51.
7. Broad, W.J. (1982) Harvard delays in reporting fraud. Science 215 (January 29): 478-82.
8. Relman, A.S. (1983) Lessons from the Darsee affair. NEJM 308 (June 9): 1415-17.
9. Culliton, B.J. (1983) Coping with fraud: The Darsee case. Science 220 (April 1): 31-35.
10. Chalk, R. (1980) AAAS Professional Ethics Project: Professional ethics activities in the scientific and engineering societies. American Association for the Advancement of Science, Washington, DC.
11. AAMC (1982) The maintenance of high ethical standards in the conduct of research. Association of American Medical Colleges, Washington, DC.
12. AAU (1983) Report of the Association of American Universities Committee on the Integrity of Research. Association of American Universities, Washington, DC.
13. Sigma Xi (1984) Honor in science. Sigma Xi, New Haven, CN.
14. Steneck, N.H. (1984) Commentary: The university and research ethics. Science, Technology, and Human Values 94(4): 6-15.
15. U.S. Congress, House. Committee on Energy and Commerce (1985) Health services and research. GPO, Washington, DC.
16. U.S. Congress, Senate. Committee on Appropriations (1985) Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations, FY85, Part 2. GPO, Washington, DC.
17. Culliton, B.J. (1985) Congress passes NIH Bill. Science 230 (November 1): 525.
18. Wigodsky, H.S. (1984) Fraud and misrepresentation in research - Whose responsibility? IRB: A Review of Human Subjects Research 6(2): 1-5.
19. PHS (1986) Policies and procedures for dealing with possible misconduct in science. National Institutes of Health, Washington, DC.
20. NSF (1987) Misconduct in science and engineering research: Final regulations. Federal Register 52 (July 1): 24466-70.
21. Holden, C. (1986) Health Service unveils fraud policy. Science 233 (July 18): 278-79.
22. Hanson, D. (1987) Testing lab fraud crimps federal drug plans. Chemical & Engineering News 65(June29): 19.
23. Koshland, D.E.J. (1987) Fraud in science. Science 235 (January 9): 141.
24. Anon. (1989) Crack down on sloppy research. Christian Science Monitor (February 21): 20:3.
25. Greenberg, D.S. (1989) Issue of scientific fraud not easily faced. Chicago Tribune (August 16): Sec 1, p 17, col 2.
26. Koshland, D.J. (1989) Zero fraud - Only with zero science. New York Times (August 19): Sec A, p 23 col 2.
27. Leary, W.E. (1989) Anxiety over the science police. New York Time (May 14): Sec 4, p 6, col 1.
28. Pollack, R.E. (1989) In science, error isn't fraud. New York Times (May 2): Sec A, p 25, col 1.
29. Racker, E. (1989) A view of misconduct in science. Nature 339 (May 11): 91-93.
30. Relman, A.S. (1989) Fraud in science: Causes and remedies. Scientific American 260 (April): 126.
31. Rosenzweig, R.M. (1989) Public policy issues in scientific fraud and misconduct. Bioscience 39 (September): 552-54.
32. Sarasohn, J. (1993) Science on trial: The whistle blower, the accused, and the Nobel laureate. St. Martin's Press, New York.
33. Anon. (1996) Rarely pure, and never simple. Economist 339 (June 22): 79.
34. Kevles, D.J. (1998) The Baltimore case: A trial of politics, science, and character. W.W. Norton, New York.
35. PHS (1989) Responsibilities of awardee and applicant institutions for dealing with and reporting possible misconduct in science. Federal Register 54 (August 8): 32446-51.
36. PHS (1990) Scientific integrity activities of the Public Health Service. PHS, Washington, DC.
37. PHS (1991) Policies and procedures for dealing with possible scientific misconduct in extramural research. Federal Register 56 (June 13): 27383-94.
38. Hallum, J.V. and Hadley, S.W. (1990) OSI: Why, what, and how? ASM News 56 (12): 647-51.
39. Wheeler, D.L. (1991) NIH office that investigates scientist's misconduct is target of widespread charges of incompetence. The Chronicle of Higher Education (May 15): A5.
40. Zurer, P.S. (1993) Appeals hearing sheds little light on AIDS virus controversy. Chemical & Engineering News 71 (July 5): 16-17.
41. Crewdson, J. (1993) Panel clears AIDS researcher. Chicago Tribune (November 5): Sec 1, p 1, col 3.
42. Palca, J. (1996) Scientific misconduct: Ill-defined, redefined. Hastings Center Report 26(September):4-11.
43. Johnson, H. (1991) Policing science. Washington Post (March 29): Sec A, p 2, col 5.
44. Woolf, P.K. (1991) Accountability and responsibility in research. Journal of Business Ethics 10 (August): 595-600.
45. Abelson, P.H. (1992) Integrity of the research process. Science 256 (May 29): 1257.
46. Borman, S. (1992) Misconduct in science: Augmenting traditional safeguards urged. Chemical & Engineering News 70 (April 27): 4-5.
47. Cimons, M. (1992) Tougher pursuit of science fraud urged. Los Angeles Times (April 23): Sec A, p 23 col 1.
48. Maechling, C.J. (1992) Investigating scientific misconduct : The laboratory is not a courtroom. Brookings Review 10 (Summer): 44-47.
49. Nelson, W.D. (1992) Science conduct board proposed. Boston Globe (April 23): 3:5.
50. Anon. (1992) Defining misconduct. Nature 356 (April 30): 730-31.
51. Greenberg, D.S. (1992) NSF fuming over Academy's misconduct report. Science & Government Report (May 15): 5-6.
52. Greenberg, D.S. (1992) Washington Perspective: Cool response for Academy's misconduct study. Lancet 339 (May 16): 1219-20
53. Buzzelli, D.E. (1993) The definition of misconduct in science: A view from NSF. Science 259 (January 29): 584-85, 647-48.
54. Rennie, D. and Gunsalus, C.K. (1993) Scientific misconduct: New definition, procedures, and office-perhaps a new leaf. JAMA 269 (7): 915-17.
55. Schachman, H.K. (1993) What is misconduct in science? Science 261(July 9): 148-49, 183.
56. Zurer, P.S. (1993) Divisive dispute smolders over definition of scientific misconduct. Chemical & Engineering News 71 (April 5): 23-25.
57. Price, A.R. (1994) Definitions and boundaries of research misconduct: Perspectives from a federal government viewpoint. Journal of Higher Education 65 (May): 286-97.
58. Zurer, P. (1994) Commission gets earful on scientific misconduct. Chemical & Engineering News 72 (November 21): 41-4.
59. Kaiser, J. (1995) Commission proposes new definition of misconduct. Science 269 (September 29): 1811.
60. Zurer, P.S. (1995) Commission on Research Integrity reshaping definition of misconduct. Chemical & Engineering News 73 (July 3): 14-15.
61. Kaiser, J. (1996) HHS is still looking for a definition. Science 272 (June 21): 1735.
62. Hileman, B. (1997) Unending debate over definition of research misconduct. Chemical & Engineering News 75 (August 4): 28.
63. Kaiser, J. (1997) NSF stakes a position on misconduct. Science 276 (June 20): 1779.
64. Kaiser, J. (1997) Storm brewing over misconduct definition. Science 275 (January 24): 467.
65. PHS, Commission on Research Integrity (1995) Integrity and misconduct in research: Report of the Commission on Research Integrity. Commission on Research Integrity, Washington, DC.
66. Medawar, P.B. (1979) Advice to a young scientist. Harper & Row, New York.
67. Zuckerman, S. (1975) Advice and responsibility, Clarendon Press, Oxford, UK.
68. St. James-Roberts, I. (1976) Are researchers trustworthy? New Scientist 71: 481-83.
69. St. James-Roberts, I. (1976) Cheating in science. New Scientist 72: 466-69.
70. Zuckerman, H. (1977) Deviant behavior and social control in science, in: Wagarin, E. (ed.), Deviance and Social Change. Sage Publications, London, pp. 87-137.
71. Weinstein, D. (1979) Fraud in science. Social Science Quarterly 59 (March 4): 639-52.
72. National Academy of Science, Committee on the Conduct of Science (1995) On being a scientist, 2nd ed., National Academy Press, Washington, DC.
73. Guston, D.H. (1992) Mentorship and the research training experience, in: Responsible Science. National Academy Press, Washington, DC, pp. 50-65.
74. PHS, NIH & ADAMHA (1989) Requirement for programs on the responsible conduct of research in national research service award institutional training programs. NIH Guide for Grants and Contracts 18:1.
75. PHS, NIH & ADAMHA (1990) Reminder and update: requirement for programs on the responsible conduct of research in national research service award institutional training programs. NIH Guide for Grants and Contracts 19:1.
76. Berg, K. and Tranoy, K.E. (1983) Research ethics. Progress in Clinical and Biological Research. Vol. 128. A.P. Liss, New York.
77. Elliott, D., and Stern, J. E., eds. (1997) Research ethics: A reader. University Press of New England for the Institute for the Study of Applied and Professional Ethics at Dartmouth College, Hanover, NH.
78. Hook, S., Kurtz, P., and Todorovich, M., eds. (1977) The Ethics of teaching and scientific research. Prometheus Books, Buffalo, NY.
79. Macrina, F.L. (1995) Scientific integrity: an introductory text with cases. ASM Press, Washington, DC.
80. Penslar, R.L., ed. (1995) Research ethics: Cases and materials. Indiana University Press, Bloomington, IN.
81. Sieber, J.E. (1992) Planning ethically responsible research: A guide for students and internal review boards, Applied Social Research Methods Series, Vol. 31. Sage Publications, Newbury Park, NY.
82. ORI (1995) Annual Report, 1994. DHHS, PHS, OASH, ORI, Washington, DC.
83. ORI (n.d.) Scientific misconduct investigations, 1993-1997. [Online] http://ori.dhhs.gov/PDF/ scientific.pdf.
84. ORI (1999) Findings of scientific misconduct: 1996-99. [Online] http://ori.dhhs.gov/ findings.htm.
85. NSF, Office of the Inspector General (1989 ff.) Semiannual report to the Congress. National Science Foundation, Washington, DC.
86. Rennie, D. (1990) Editorial peer review in biomedical publications: The First International Congress. JAMA 263 (March 9): 1317.
87. Swazey, J.P. (1993) Ethical problems in academic research. American Scientist 81 (November/ December): 542-53.
88. National Academy of Sciences. Panel on Scientific Responsibility and the Conduct of Research. Committee on Science, Engineering and Public Policy (1992) Responsible science: Ensuring the integrity of the research process. 2 Vols. National Academy Press, Washington, D.C.
89. Gardner, M.J. (1990) An exploratory study of statistical assessment of papers published in the British Medical Journal. JAMA 263 (March 9): 1355-57.
90. McNutt, R.A., et al. (1990) The effects of blinding on the quality of peer review. JAMA 263 (March 9): 1371-76.
91. Stelfox, H.T., Chua, G., O'Rourke, K., and Detsky, A.S. (1998) Conflict of interest in the debate over calcium-channel antagonists. NEJM 338 (January 8): 101-06.
92. Anon. (1998) Correspondence: Conflict of interest in the debate over calcium-channel antagonists. NEJM 338 (June 4): 1696-98.
93. Campbell, E.G., Louis, K.S., and Blumenthal, D. (1998) Look a gift horse in the mouth: Corporate gifts supporting life sciences research. JAMA 279 (April 1): 995-99.
94. Gold, M. (1986) A conspiracy of cells. SUNY Press, Albany, NY.
95. Friedman, P.J. (1990) Correcting the literature following fraudulent publication. JAMA 263 (March 9): 1416-19.
96. Pfeifer, M.P. and Snodgrass, G.L. (1990) The continued use of retracted, invalid scientific literature. JAMA 263 (March 9): 1420-23.
97. Garfield, E. and Welljams-Dorof, A. (1990) The impact of fraudulent research on the scientific literature. JAMA 26 (March 9): 1424-27.
98. Kalichman, M.W. and Friedman, P.J. (1992) A pilot study of biomedical trainees' perceptions concerning research ethics. Academic Medicine 67 (November 11): 769-75.
99. Eastwood, S., Derish, P., Leash, E. and Ordway, S. (1996) Ethical issues in biomedical research: Perceptions and practices of postdoctoral research fellows responding to a survey. Science and Engineering Ethics 2 (1): 89-114.
100. Ehlers, V.J. (1998) The future of U.S. science policy. Science 279 (January 16): 302.