Quantification of intracellular metabolic fluxes from fractional enrichment and 13C-13C coupling constraints on the isotopomer distribution in labeled biomass components

Metabolic Engineering

Volumn 1, Issue 2, 1999, Pages 166-179

  Schmidt, Karsten ^a,c   Nørregaard, Lars C ^a   Pedersen, Bent ^b   Meissner, Axel ^b   Duus, Jens Ø ^b   Nielsen, Jens Ø ^a   Villadsen, John ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b CARLSBERG LABORATORY   (Denmark)

^c DSM Deutschland GmbH   (Germany)

Author keywords

2D NMR spectroscopy; Aspergillus niger; Isotopomer mapping matrices; Isotopomer modeling; Metabolic flux analysis; Monte Carlo simulation; PCA

Indexed keywords

ASPERGILLUS NIGER;

CARBON; CHITIN; GLUCAN 1,4 ALPHA GLUCOSIDASE;

ARTICLE; ASPERGILLUS NIGER; BIOMASS; BIOSYNTHESIS; CITRIC ACID CYCLE; COMPUTER SIMULATION; ISOTOPE LABELING; METABOLISM; METHODOLOGY; MONTE CARLO METHOD; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PENTOSE PHOSPHATE CYCLE;

ASPERGILLUS NIGER; BIOMASS; CARBON ISOTOPES; CHITIN; CITRIC ACID CYCLE; COMPUTER SIMULATION; GLUCAN 1,4-ALPHA-GLUCOSIDASE; ISOTOPE LABELING; MAGNETIC RESONANCE SPECTROSCOPY; MONTE CARLO METHOD; PENTOSE PHOSPHATE PATHWAY; SUBSTRATE CYCLING;

EID: 0033107837     PISSN: 10967176     EISSN: None     Source Type: Journal    
DOI: 10.1006/mben.1999.0114     Document Type: Article

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