Prostaglandin E2 stimulates the formation of mineralized bone nodules by a cAMP-independent mechanism in the culture of adult rat calvarial osteoblasts

Journal of Cellular Biochemistry

Volumn 73, Issue 1, 1999, Pages 36-48

  Kaneki, Hiroyuki ^a   Takasugi, Ikuko ^a   Fujieda, Masaki ^a   Kiriu, Michiaki ^a   Mizuochi, Shigeki ^a   Ide, Hayao ^a  

^a TOHO UNIVERSITY   (Japan)

Author keywords

Calmodulin; cAMP; Mineralized bone nodule; Osteoblasts; Phosphoinositide turnover; Prostaglandin E2 (PGE2)

Indexed keywords

ADENYLATE CYCLASE; ALKALINE PHOSPHATASE; CALMODULIN; COLLAGEN; CYCLIC AMP; FORSKOLIN; INOSITOL 1,4,5 TRISPHOSPHATE; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; PHOSPHATIDYLINOSITIDE; PHOSPHODIESTERASE; PROSTAGLANDIN E2; PROTEIN KINASE (CALCIUM,CALMODULIN); ISOBUTYLMETHYLXANTHINE; PHOSPHODIESTERASE INHIBITOR;

ANIMAL CELL; ARTICLE; BONE MINERALIZATION; CALCIUM CELL LEVEL; CALVARIA; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; COLLAGEN SYNTHESIS; DOSE RESPONSE; ENZYME ACTIVITY; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; RAT; ANIMAL; BONE; CYTOLOGY; DRUG EFFECT; FEMALE; METABOLISM; WISTAR RAT;

1-METHYL-3-ISOBUTYLXANTHINE; ANIMALS; BONE AND BONES; CELL DIFFERENTIATION; CELLS, CULTURED; CYCLIC AMP; DINOPROSTONE; FEMALE; OSTEOBLASTS; PHOSPHODIESTERASE INHIBITORS; RATS; RATS, WISTAR;

EID: 0033106493     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19990401)73:1<36::AID-JCB5>3.0.CO;2-F     Document Type: Article

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