Genomic structure and chromosomal localization of the mouse persyn gene

Genomics

Volumn 56, Issue 2, 1999, Pages 224-227

  Alimova Kost, Maria V ^a,b   Ninkina, Natalia N ^c,d   Imreh, Stefan ^a   Gnuchev, Nikolai V ^c   Adu, Jimi ^d   Davies, Alun M ^d,e   Buchman, Vladimir L ^b,d  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^c INSTITUTE OF GENE BIOLOGY   (Russian Federation)

^d UNIVERSITY OF ST ANDREWS   (United Kingdom)

^e Neuropa Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 14; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOCATION; GENE SEQUENCE; MOLECULAR CLONING; MOUSE; NERVE DEGENERATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS; RODENTIA;

EID: 0033106425     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1998.5674     Document Type: Article

References (19)

1. Buchman V. L. Synucleins: Clues to mechanisms of neurodegenerative diseases? Mol. Biol. 32:1998;592-597.
2. Buchman V. L., Adu J., Pinõn L. G. P., Ninkina N. N., Davies A. M. Persyn, a member of the synuclein family, influences neurofilament network integrity. Nature Neurosci. 1:1998;101-103.
3. Buchman V. L., Hunter H. J. A., Pinõn L. G. P., Thompson J., Privalova E. M., Ninkina N. N., Lowe J., Davies A. M. Persyn, a member of the synuclein family, has a distinct pattern of expression in the developing nervous system. J. Neurosci. 18:1998;9335-9341.
4. Chase T. N. A gene for Parkinson disease. Arch. Neurol. 54:1997;1156-1157.
5. Clayton D. F., George J. M. The synucleins: A family of proteins involved in synaptic function, plasticity, neurodegeneration and disease. Trends Neurosci. 21:1998;249-254.
6. Cleveland D. W. Neuronal growth and death: Order and disorder in the axoplasm. Cell. 84:1996;663-666.
7. Donaghy M., King R. H., Thomas P. K., Workman J. M. Abnormalities of the axonal cytoskeleton in giant axonal neuropathy. J. Neurocytol. 17:1988;197-208.
8. Heintz N., Zoghbi H. α-synuclein - A link between Parkinson and Alzheimer diseases? Nat. Genet. 16:1997;325-327.
9. Hsu L. J., Mallory M., Xia Y., Veinbergs I., Hashimoto M., Yoshimoto M., Thal L. J., Saitoh T., Masliah E. Expression pattern of synucleins (non-Aβ component of Alzheimer's disease amyloid precursor protein/α-synuclein) during murine brain development. J. Neurochem. 71:1998;338-344.
10. Jakes R., Spillantini M. G., Goedert M. Identification of two distinct synucleins from human brain. FEBS Lett. 345:1994;27-32.
11. Ji H., Liu Y. E., Jia T., Wang M., Liu J., Xiao G., Joseph B. K., Rosen C., Shi Y. E. Identification of a breast cancer-specific gene, BCSG1, by direct differential cDNA sequencing. Cancer Res. 57:1997;759-764.
12. Maroteaux L., Scheller R. H. The rat brain synucleins: Family of proteins transiently associated with neuronal membrane. Mol. Brain Res. 11:1991;335-343.
13. Nakajo S., Shioda S., Nakai Y., Nakaya K. Localization of phosphoneuroprotein 14 (PNP 14) and its mRNA expression in rat brain determined by immunocytochemistry and in situ hybridization. Mol. Brain Res. 27:1994;81-86.
14. Ninkina N., Alimova-Kost M. V., Paterson J. W. E., Delaney L., Cohen B. B., Imreh S., Gnuchev N. V., Davies A. M., Buchman V. L. Organisation, expression and polymorphism of the human persyn gene. Hum. Mol. Genet. 7:1998;1417-1424.
15. Nussbaum R. L., Polymeropoulos M. H. Genetics of Parkinson's disease. Hum. Mol. Genet. 6:1997;1687-1691.
16. Petersen, K. Olesen, O. F. Perregaard, J. K. Mikkelsen, J. D. 1997, Synuclein/NACP mRNA expression in rat hippocampus and cerebral cortex during development, In, Abstracts of the 27th Annual Meeting of the Society for Neuroscience, New Orleans, LA, 23, 267.
17. Shibayama-Imazu T., Okahashi I., Omata K., Nakajo S., Ochiai H., Nakai Y., Hama T., Nakamura Y., Nakaya K. Cell and tissue distribution and developmental change of neuron specific 14 kDa protein (phosphoneuroprotein 14). Brain Res. 622:1993;17-25.
18. Trojanowski J. Q., Lee V. M. Aggregation of neurofilament and α-synuclein proteins in Lewy bodies: Implications for the pathogenesis of Parkinson disease and Lewy body dementia. Arch. Neurol. 55:1998;151-152.
19. Uéda K., Fukushima H., Masliah E., Xia Y., Iwai A., Yoshimoto M., Otero D. A. C., Kondo J., Ihara Y., Saitoh T. Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc. Natl. Acad. Sci. USA. 90:1993;11282-11286.