Unusual hydroxy-γ-sultone byproducts of steroid 21- methanesulfonylation. An efficient synthesis of mometasone 17-furoate (Sch 32088)

Tetrahedron

Volumn 55, Issue 11, 1999, Pages 3355-3364

  Draper, Richard W ^a   Bin, Hu ^a   McPhail, Andrew T ^a,b   Puar, Mohindar S ^a   Vater, Eugene J ^a   Weber, Lois ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

17ALPHA,21 DIHYDROXY 16ALPHA METHYL 9BETA,11BETA OXIDOPREGNA 1,4 DIENE 3,20 DIONE; 21 HYDROXY 20 KETOSTEROID; 4 DIMETHYLAMINOPYRIDINE; MOMETASONE FUROATE; SULTONE; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CRYSTALLIZATION; DRUG SYNTHESIS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

EID: 0033105294     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(98)01146-6     Document Type: Article

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