Early effects of hormone replacement therapy on bone

Bone

Volumn 24, Issue 3, 1999, Pages 245-248

  Patel, S ^a,b   Pazianas, M ^c   Tobias, J ^d   Chambers, T J ^e   Fox, S ^e   Chow, J ^e  

^a ST HELIER HOSPITAL   (United Kingdom)

^b ST GEORGE S HOSPITAL   (United Kingdom)

^c University of Philadelphia   (United States)

^d BRISTOL ROYAL INFIRMARY   (United Kingdom)

^e ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Bone formation; Estrogen; Hormone replacement therapy; Postmenopausal osteoporosis

Indexed keywords

BIOCHEMICAL MARKER; DYDROGESTERONE; ESTRADIOL VALERATE; ESTROGEN; TETRACYCLINE;

ADULT; AGED; ARTICLE; BONE BIOPSY; BONE TURNOVER; CHEMICAL LABELING; CLINICAL ARTICLE; CONTROLLED STUDY; ESTROGEN THERAPY; FEMALE; HORMONE SUBSTITUTION; HUMAN; ILIAC CREST; MORPHOMETRICS; OSSIFICATION; OSTEOLYSIS; POSTMENOPAUSE OSTEOPOROSIS; STATISTICAL ANALYSIS;

AMINO ACIDS; BIOLOGICAL MARKERS; BONE DENSITY; BONE DEVELOPMENT; DENSITOMETRY, X-RAY; DRUG THERAPY, COMBINATION; DYDROGESTERONE; ESTRADIOL; ESTROGEN REPLACEMENT THERAPY; FEMALE; FEMUR NECK; FOLLICLE STIMULATING HORMONE; HUMANS; ILIUM; LUMBAR VERTEBRAE; LUTEINIZING HORMONE; MIDDLE AGED; OSTEOPOROSIS, POSTMENOPAUSAL; TETRACYCLINE;

EID: 0033105075     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(98)00177-X     Document Type: Article

References (26)

1. Abe T., Chow J.W.M., Lean J.M., Chambers T.J. Estrogen does not restore bone lost after ovariectomy in the rat. J Bone Miner Res. 8:1993;831-838.
2. Cann, C. E., Arnaud, C. D., Roe, B., and Sanchez, S. Localized bone response to drugs may be modulated by local strains. In: 27th International Sun Valley Workshop on Hard Tissue Biology, Sun Valley, ID, 1997.
3. Chow J., Lean J.M., Chambers T.J. 17 beta-estradiol stimulates cancellous bone formation in female rats. Endocrinology. 130:1992;3025-3032.
4. Chow J., Tobias J.H., Colston K.W., Chambers T.J. Estrogen maintains trabecular bone volume in rats not only by suppression of bone resorption but also by stimulation of bone formation. J Clin Invest. 89:1992;74-78.
5. Dhuper S., Warren M.P., Brooks-Gunn J., Fox R. Effects of hormonal status on bone density in adolescent girls. J Clin Endocrinol Metab. 71:1990;1083-1088.
6. Hannon R., Blumsohn A., Naylor K., Eastell R. Response of biochemical markers of bone turnover to hormone replacement therapy Impact of biological variability . J Bone Miner Res. 13:1998;1124-1133.
7. Hodsman A.B., Steer B.M. Early hisotmorphometric changes in response to parathyroid hormone therapy in osteoporosis Evidence for de novo bone formation on quiescent cancellous surfaces . Bone. 14:1993;523-527.
8. Jagger C.J., Chow J.W.M., Chambers T.J. Estrogen suppresses activation but enhances formation phase of osteogenic response to mechanical stimulation in rat bone. J Clin Invest. 98:1996;2351-2357.
9. Jee W.S., Ma Y.F. The in vivo anabolic actions of prostaglandins in bone. Bone. 21:1997;297-304.
10. Lufkin E.G., Wahner H.W., O'Fallon W.M., Hodgson S.F., Kotowicz M.A., Lane A.W., Judd H.L., Caplan R.H., Riggs B.L. Treatment of postmenopausal osteoporosis with transdermal estrogen. Ann Intern Med. 117:1992;1-9.
11. Morishima A., Grumbach M.M., Simpson E.R., Fisher C., Qin K. Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens. J Clin Endocrinol Metabol. 80:1995;3689-3698.
12. Bilezikian J.P., Morishima A., Bell J., Grombach M.M. Increased bone mass as a result of estrogen therapy in a man with aromatase deficiency. N Engl J Med. 339:1998;599-603.
13. Parfitt A.M., Drenzer M.K., Glorieux F.H., et al. Bone histomorphometry: Standardisation of nomenclature, symbols and units Report of the ASBMR Histomorphometry Nomenclature Committee . J Bone Miner Res. 2:1987;595-610.
14. Patel S. Current and potential future drug treatment for osteoporosis. Ann Rheum Dis. 55:1996;700-714.
15. Simmons D.J., Pankovich A.M. Estrogen induced intramedullary bone formation in Japanese quail. Endocrinology. 74:1964;646-648.
16. Sims N.A., Morris H.A., Moore R.J., Durbridge T.C. Estradiol treatment transiently increases trabecular bone volume in ovariectomized rats. Bone. 19:1996;455-461.
17. Smith E.P., Boyd J., Frank G.R., Takahashi H., Cohen R.M., Specker B., Williams T.C., Lubahn D.B., Korach K.S. Estrogen resistance caused by a mutation in the estrogen receptor gene in man. N Eng J Med. 331:1994;1056-1061.
18. Steiniche T., Hasling C., Charles P., Eriksen E.F., Mosekilde L., Melsen F. A randomised study on the effects of estrogen/gestagen or high dose oral calcium on trabecular bone remodeling in postmenopausal osteoporosis. Bone. 10:1989;313-320.
19. Tobias, J. H., Chow, J., Colston, K. W., and Chambers, T. J. High concentrations of 17 beta-estradiol stimulate trabecular bone formation in adult female rats. Endocrinology 128:428-412; 1991.
20. Tobias J.H., Laversuch C.J., Chambers T.J., Gallagher A.C. Aminohexane bisphosphonate suppresses bone turnover in postmenopausal women more rapidly than oestrogen-gestagen therapy. Br J Rheumatol. 35:1996;636-641.
21. Turner R.T., Riggs B.L., Spelsberg T.C. Skeletal effects of estrogen. Endocrine Rev. 15:1994;275-300.
22. Vedi S., Ballard P., Bord S., Purdie D.W., Compston J.E. Anabolic effects of high dose oestrogen therapy in postmenopausal women A histomorphometric study . J Bone Miner Res. 12:1997;1520.
23. Vedi S., Compston J.E. The effects of long-term hormone replacement therapy on bone remodeling in postmenopausal women. Bone. 19:1996;535-539.
24. Wahab M., Ballard P., Purdie D.W., Cooper A., Willson J.C. The effect of long term oestradiol implantation on bone mineral density in postmenopausal women who have undergone hysterectomy and bilateral oophorectomy. Br J Obstet Gynaecol. 104:1997;728-731.
25. Westerlind K.C., Wakley G.K., Evans G.L., Turner R.T. Estrogen does not increase bone formation in growing rats. Endocrinology. 133:1993;2924-2934.
26. World Health Organisation . Assessment of Fracture Risk and Its Application to Screening for Postmenopausal Osteoporosis WHO Technical Report Series . 1994;WHO, Geneva.