Decreases in cAMP phosphodiesterase activity in hepatocytes cultured with herbimycin A due to cellular microtubule polymerization related to inhibition of tyrosine phosphorylation of α-tubulin

European Journal of Biochemistry

Volumn 260, Issue 2, 1999, Pages 398-408

  Ishibashi, Kaname ^a   Fujioka, Toshiyuki ^a   Ui, Michio ^a,b  

^a INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

CAMP phosphodiesterase; Hepatocytes; Herbimycin A; Microtubules; Phosphorylation of protein tyrosine residues

Indexed keywords

4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; ALPHA TUBULIN; COLCHICINE; CYCLIC AMP; CYCLIC AMP PHOSPHODIESTERASE; FORSKOLIN; GLUCAGON; HERBIMYCIN A; ISOBUTYLMETHYLXANTHINE; PACLITAXEL; ROLIPRAM; TYROSINE; VINBLASTINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CULTURE MEDIUM; ENZYME ACTIVITY; IMMUNOBLOTTING; LIVER CELL CULTURE; MALE; MICROTUBULE; MICROTUBULE ASSEMBLY; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; RAT;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; BENZOQUINONES; CELL-FREE SYSTEM; CELLS, CULTURED; CYCLIC AMP; ENZYME INHIBITORS; FORSKOLIN; GLUCAGON; LACTAMS, MACROCYCLIC; LIVER; MALE; MICROTUBULES; PHOSPHORYLATION; POLYMERS; PROTEIN-TYROSINE KINASES; QUINONES; RATS; RATS, WISTAR; TUBULIN;

ANIMALIA;

EID: 0033104887     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00163.x     Document Type: Article

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