Evaluation of commercial and purified Pluronic(TM) F-68 in a human blood neutrophil bioassay

Artificial Cells, Blood Substitutes, and Immobilization Biotechnology

Volumn 27, Issue 2, 1999, Pages 171-177

  Edwards, C M ^a   Gambaretto, G P ^b   Conte, L ^b   Lowe, K C ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BLOOD; CHEMILUMINESCENCE; COPOLYMERS; FRACTIONATION; POLYETHYLENES; POLYPROPYLENES; SILICA GEL; STIMULATED EMISSION; SUPERCRITICAL FLUID EXTRACTION;

NEUTROPHIL; SUPERCRITICAL FLUID FRACTIONATION;

BLOOD SUBSTITUTES;

PHORBOL 13 ACETATE 12 MYRISTATE; POLOXAMER; SILICA GEL;

ARTICLE; BIOASSAY; CHEMOLUMINESCENCE; FRACTIONATION; NEUTROPHIL;

EID: 0033104664     PISSN: 10731199     EISSN: None     Source Type: Journal    
DOI: 10.3109/10731199909117691     Document Type: Article

References (19)

1. Lowe, K.C. Perfluorochemicals in vascular medicine. Vasc. Med. Rev. 5, 15-32 (1994).
2. Zuck, T.F. and Riess, J.G. Current status of injectable oxygen carriers. Crit. Rev. Clin. Lab. Sci. 31, 295-324 (1994).
3. Lowe, K.C. Perfluorochemical respiratory gas carriers: applications in medicine and biotechology. Science Prog. 80, 169-193 (1997).
4. Ingram, D.A., Forman, M.B. and Murray, J.J. Phagocytic activation of human neutrophils by the detergent component of Fluosol. Am. J. Pathol. 140, 1081-1087 (1992).
5. Ingram, D.A., Forman, M.B. and Murray, J.J. Activation of complement by Fluosol attributable to the Pluronic detergent micelle structure. J. Cardiovasc. Pharmacol. 22, 456-461 (1992).
6. Forman, M.B., Ingram, D.A. and Murray, J.J. Attenuation of myocardial reperfusion injury by perfluorochemical emulsions. Clin. Hemorheol. 12, 121-140 (1992).
7. Forman, M.B., Pitarys, C.J., Vildibill, H.D., Lambert, T.L., Ingram, D.A., Virmani, R. and Murray, J.J. Pharmacologic perturbation of neutrophils by Fluosol results in a sustained reduction in infarct size in the canine model of reperfusion. J. Am. Coll. Cardiol. 19, 205-216 (1992).
8. Schaer, G.L., Hursey, T.L., Abrahams, S.L., Buddemeier, K., Ennis, B., Rodriguez, R., Hubbell, J.P., Moy, J. and Parrillo, J.E. Reduction in reperfusion-induced myocardial injury in dogs by RheothRx® Injection (Poloxamer 188 N.F.), a hemorheological agent that alters neutrophil function. Circulation 90, 2964-2975 (1994).
9. Schaer, G.L., Spaccavento, L.J., Browne, K.F., Krueger, K.A., Krichbaum, D., Phelan, J.M., Fletcher, W.O., Grines, C.L., Edwards, S., Jolly, M.K. and Gibbons, R.J. Beneficial effects of RheothRx Injection in patients receivinf thrombolytic therapy for acute myocardial infarction. Circulation 94, 298-307 (1996).
10. Riess, J.G. and Le Blanc, M. Preparation of perfluorochemical emulsions for biomedical use: principles, materials and methods. In: Blood Substitutes: Preparation, Physiology and Medical Applications, Lowe, K.C. (Ed.), pp. 94-129, Chichester, Ellis Horwood, 1988.
11. Bentley, P.K., Davis, S.S., Johnson, O.L., Lowe, K.C. and Washington, C. Purification of Pluronic F-68 for perfluorochemical emulsification. J. Pharm. Pharmac. 41, 661-663 (1989).
12. Neilson, C.P., Crowley, J.J., Vestal, R.E. and Connolly, M.J. Impaired beta-adrenoceptor function, increased leukocyte respiratory burst, and bronchial hyperresponsiveness. J. Allergy Clin. Immunol. 90, 825-832 (1992).
13. Lane, T.A. and Krukonis, V. Reduction in the toxicity of a component of an artificial blood substitute by supercritical fluid fractionation. Transfusion 28, 375-378 (1988).
14. Edwards, C.M., Lowe, K.C., Trabelsi, H., Lucas, P. and Cambon, A. Novel fluorinated surfactants for perfluorochemical emulsification: biocompatibility assessments of glycosidic and polyol derivatives. Art. Cells, Blood Subs., and Immob. Biotech., 25, 255-260 (1997).
15. Snedecor, G.W. and Cochran, W.G. Statistical Methods, 8th Edn., Ames, Iowa State College Press, 1989.
16. Cawrse, N.W., de Pomerai, D.I. and Lowe, K.C. Effects of Pluronic F-68 on 2-deoxyglucose uptake and amino acid incorporation into chick embryonic fibroblasts in vitro. Biomed. Sci., 2, 180-182 (1991).
17. King, A.T., Davey, M.R., Mellor, I.R., Mulligan, B.J. and Lowe, K.C. Surfactant effects on yeast cells. Enzyme Microb. Technol., 13, 148-153 (1991).
18. ICI Surfactant Data Sheet, 'Synperonic' PE/F68, TPDS7KB2 (1994).
19. Smith, T.M., Steinhorn, D.M., Thusu, K., Fuhrman B.P. and Dandona, P. A liquid perfluorochemical decreases the in vitro production of reactive oxygen species by alveolar macrophages. Crit. Care Med. 23, 1533-1539 (1995).