Germ cell development in the XXY mouse: Evidence that X chromosome reactivation is independent of sexual differentiation

Developmental Biology

Volumn 207, Issue 1, 1999, Pages 229-238

  Mroz, K ^a   Carrel, L ^a   Hunt, P A ^a  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ANEUPLOIDY; ANIMAL TISSUE; ARTICLE; FEMALE; GAMETOGENESIS; GENE EXPRESSION; MALE; NONHUMAN; PRIORITY JOURNAL; SEX DIFFERENTIATION; X CHROMOSOME INACTIVATION;

ANIMALIA; MAMMALIA;

EID: 0033104435     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1998.9160     Document Type: Article

References (50)

1. Agulnik A. I., Mitchell M. J., Lerner J. L., Woods D. R., Bishop C. E. A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens. Hum. Mol. Genet. 3:1994a;873-878.
2. Agulnik A. I., Mitchell M. J., Mattei M.-G., Borsani G., Avner P. A., Lerner J. L., Bishop C. E. A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human. Hum. Mol. Genet. 3:1994b;879-884.
3. Bond D. J., Chandley A. C. Aneuploidy. 1983;Oxford Univ. Press, New York.
4. Bourne H., Stern K., Clarke G., Pertile M., Speirs A., Baker G. Delivery of normal twins following the intracytoplasmic injection of spermatozoa from a patient with 47, XXY Klinefelter's syndrome. Hum. Reprod. 12:1997;2447-2450.
5. Boyle A. L., Ward D. C. Isolation and initial characterization of a large repeat sequence element specific to mouse chromosome 8. Genomics. 12:1992;517-525.
6. Brinster R. L., Avarbock M. R. Germline transmission of donor haplotype following spermatogonial transplantation. Proc. Natl. Acad. Sci. USA. 91:1994;11303-11307.
7. Brinster R. L., Zimmermann J. W. Spermatogenesis following male germ-cell transplantation. Proc. Natl. Acad. Sci. USA. 91:1994;11298-11302.
8. Buehr M., McLaren A. Isolation and culture of primordial germ cells. Methods in Enzymology: Guide to Techniques in Mouse Development. 1993;Academic Press, San Diego. p. 58-77.
9. Burgoyne P. S., Baker T. G. Perinatal oocyte loss in XO mice and its implications for the aetiology of gonadal dysgenesis in XO women. J. Reprod. Fertil. 75:1985;633-645.
10. Burgoyne P. S., Buehr M., Koopman P., Rossant J., McLaren A. Cell-autonomous action of the testis-determining gene: Sertoli cells are exclusively XY in XX/XY chimaeric mouse testes. Development. 102:1988;443-450.
11. Burgoyne P. S., Mahadevaiah S. K. Unpaired sex chromosomes and gametogenic failure. Sumner A. T., Chandley A. C. Chromosomes Today. 1993;243-263 Chapman and Hall, London.
12. Carrel L., Clemson C. M., Dunn J. M., Miller A. P., Hunt P. A., Lawrence J. B., Willard H. F. X inactivation analysis and DNA methylation studies of the ubiquitin activating enzyme E1 and PCTAIRE-1 genes in human and mouse. Hum. Mol. Genet. 5:1996a;391-401.
13. Carrel L., Hunt P. A., Willard H. F. Tissue and lineage-specific variation in inactive X chromosome expression of the murineSmcx. Hum. Mol. Genet. 5:1996b;1361-1366.
14. Cattanach B., Pollard C., Hawkes S. Sex reversed mice: XX and XO males. Cytogenetics. 10:1971;318-337.
15. Davis C. A. Whole-Mount Immunohistochemistry. 1993;Academic Press, London.
16. Disteche C. M., Candy S. L., Aldre D. A. Translocation and amplification of an X-chromosome DNA repeat in inbred strains of mice. Nucleic Acids Res. 15:1987;4393-4401.
17. Downie N. M., Heath R. W. Basic Statistical Methods. 1983;Harper and Row, Philadelphia.
18. Enders G. C., May J. J. Developmentally regulated expression of a mouse germ cell nuclear antigen examined from embryonic day 11 to adult in male and female mice. Dev. Biol. 163:1994;331-340.
19. Epstein C. J. The Consequences of Chromosome Imbalance. 1986;Cambridge Univ. Press, Cambridge.
20. Estop A., Munne S., Cieply K., Vandermark K., Lamb A., Fisch H. Meiotic products of a Klinefelter 47,XXY male as determined by sperm fluorescence in-situ hybridization analysis. Hum. Reprod. 13:1998;124-127.
21. Foresta C., Galeazzi C., Bettella A., Stella M., Scandellari C. High incidence of sperm sex chromosome aneuploidies in two patients with Klinefelter's syndrome. J. Clin. Endocrinol. Metab. 83:1998;203-205.
22. Goetz P., Chandley A. C., Speed R. M. Morphological and temporal sequence of meiotic prophase development at puberty in the male mouse. J. Cell Sci. 65:1984;249-263.
23. Guttenbach M., Michelmann H. W., Hinney B., Engel W., Schmid M. Segregation of sex chromosomes into sperm nuclei in a man with 47, XXY Klinefelter's karyotype: A FISH analysis. Hum. Genet. 99:1997;474-477.
24. Handel M. A., Hunt P. A. Sex chromosome pairing and activity during mammalian meiosis. BioEssays. 14:1992;817-822.
25. Harari O., Gronow M., Bourne H., Johnston I., Baker G. High fertilization rate with intracytoplasmic sperm injection in mosaic Klinefelter's syndrome. Fertil. Steril. 63:1995;182-184.
26. Hunt P. A., Eicher E. M. Fertile male mice with three sex chromosomes: Evidence that infertility in XXY male mice is an effect of two Y chromosomes. Chromosoma. 100:1991;293-299.
27. Hunt P. A., Worthman C., Levinson H., Stallings J., LeMaire R., Mroz K., Park C., Handel M. A. Germ cell loss in the XXY male mouse: Altered X-chromosome dosage affects prenatal development. Mol. Reprod. Dev. 49:1998;101-111.
28. a. Dev. Biol. 199:1998;235-244.
29. Latham K. E. X chromosome inprinting and inactivation in the early mammalian embryo. Trends Genet. 12:1996;134-138.
30. Lyon M. Mechanism and evolutionary origin of variable X-chromosome activity in mammals. Proc. R. Soc. London Ser. B. 187:1974;243-268.
31. McKee B. D., Handel M. A. Sex chromosomes, recombination, and chromatin conformation. Chromosoma. 102:1993;71-80.
32. McLaren A. The fate of germ cells in the testis of fetal sex-reversed mice. J. Reprod. Fertil. 61:1981;461-467.
33. McLaren A. Of MIS and the mouse. Nature. 345:1990;111.
34. McLaren A., Monk M. X-Chromosome activity in the germ cells of sex-reversed mouse embryos. J. Reprod. Fertil. 63:1981;533-537.
35. McLaren A., Southee D. Entry of mouse embryonic germ cells into meiosis. Dev. Biol. 187:1997;107-113.
36. Monk M., McLaren A. X-chromosome activity in foetal germ cells of the mouse. J. Embryol. Exp. Morph. 63:1981;75-84.
37. Mroz, K. Hassold, T. J. Hunt, P. A. Meiotic Aneuploidy in the XXY Mouse: Evidence that a compromised testicular environment increases the incidence of meiotic errors, In, Human Reproduction.
38. Müller J., Skakkebaek N. E., Ratcliffe S. G. Quantified testicular histology in boys with sex chromosome abnormalities. Int. J. Androl. 18:1995;57-62.
39. Nagamine C. M., Capehart J., Carlisle C., Chang D. Ovotestes in B6-XX,Sxr. Dev. Biol. 196:1998;24-32.
40. Okuda T., Cleveland J. L., Downing J. R. PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase family. Oncogene. 7:1992;2249-2258.
41. Palmer S. J., Burgoyne P. S. In situ analysis of fetal, prepuberal and adult XX-XY chimaeric mouse testes: Sertoli cells are predominantly, but not exclusively, XY. Development. 112:1991;265-268.
42. Palmero G. D., Schlegel P. N., Sills E. S., Veeck L. L., Zaninovic N., Menendez S., Rosenwaks Z. Births after intracytoplasmic injection of sperm obtained by testicular extraction from men with nonmosaic Klinefelter's syndrome. N. Engl. J. Med. 338:1998;588-590.
43. Patek C. E., Kerr J. B., Gosden R. G., Jones K. W., Hardy K., Muggleton-Harris A. L., Hanyside A. H., Whittingham D. G., Hooper M. L. Sex chimaerism, fertility and sex determination in the mouse. Development. 113:1991;311-325.
44. Peters A. H. F. M., Plug A. W., van Vugt M. J., de Boer P. A drying down technique for spreading of mammalian meiocytes from the male and female germ line. Chromosome Res. 5:1997;1-3.
45. Singh L., Matsukuma S., Jones K. W. Testis development in a mouse with 10% of XY cells. Dev. Biol. 122:1987;287-290.
46. Speed R. M. Oocyte development in XO foetuses of man and mouse: The possible role of heterologous X-chromosome pairing in germ cell survival. Chromosoma. 94:1986;115-124.
47. Takagi N., Abe K. Detrimental effects of two active X chromosomes on early mouse development. Development. 109:1990;189-201.
48. Tam P. P. L., Zhou S. X., Tan S.-S. X-chromosome activity of the mouse primordial germ cells revealed by the expression of an X-linked lacZ transgene. Development. 120:1994;2925-2932.
49. Wolf N. G., Abdul-Karim F. W., Schork N. H., Schwartz S. Origins of heterogeneous ovarian carcinomas: A molecular cytogenetic analysis of histologically benign, low malignant potential and fully malignant components. Am. J. Pathol. 149:1996;511-520.
50. Zamboni L., Upadhyay S. Germ cell differentiation in mouse adrenal glands. J. Exp. Zool. 228:1983;173-193.