Variability in the binding of anti-MAG and anti-SGPG antibodies to target antigens in demyelinating neuropathy and IgM paraproteinemia

Journal of Neuroimmunology

Volumn 95, Issue 1-2, 1999, Pages 174-184

  Weiss, M D ^a   Dalakas, M C ^b   Lauter, C J ^a   Willison, H J ^a   Quarles, R H ^a  

^a Lab Cell Molec Biophys   (United States)

^b Neuromuscular Diseases Section   (United States)

Author keywords

Anti MAG; Anti SGPG; Antibodies neuropathy; Variability

Indexed keywords

GLYCOCONJUGATE; IMMUNOGLOBULIN M;

ADULT; ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DEMYELINATING NEUROPATHY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNE RESPONSE; IMMUNOCHEMISTRY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOTHERAPY; PARAPROTEINEMIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SENSORIMOTOR FUNCTION;

AGED; ANTIBODY SPECIFICITY; AUTOANTIBODIES; CENTRAL NERVOUS SYSTEM; CHROMATOGRAPHY, THIN LAYER; DEMYELINATING DISEASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLOBOSIDES; HUMANS; IMMUNOGLOBULIN M; IMMUNOGLOBULINS, INTRAVENOUS; MALE; MIDDLE AGED; MYELIN SHEATH; MYELIN-ASSOCIATED GLYCOPROTEIN; PARAPROTEINEMIAS; PERIPHERAL NERVOUS SYSTEM;

EID: 0033104089     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(98)00247-1     Document Type: Article

References (45)

1. Ariga T., Kohriyama T., Freddo L., Latov N., Saito K., Kon T., Ando S., Suzuki M., Hemling M.E., Rinehart K.L., Kusunoki S., Yu R. Characterization of sulfated glucuronic acid containing glycolipids reacting with IgM M proteins in patients with neuropathy. J. Biol. Chem. 262:1987;848-853.
2. Bollensen E., Steck A.J., Schachner M. Reactivity with the peripheral myelin glycoprotein P0 in serum from patients with monoclonal IgM gammopathy and polyneuropathy. Neurology. 38:1988;1266-1270.
3. Blume G., Pestronk A., Goodnough L.T. Anti-Mag antibody-associated polyneuropathies: improvement following immunotherapy with monthly plasma exchange and IV cyclophosphamide. Neurology. 45:1995;1577-1580.
4. Brouet J.C., Mariette X., Chevalier A., Hauttecoeur B. Determination of the affinity of human IgM for myelin-associated glycoprotein and sulfated glucuronic acid paragloboside. J. Neuroimmunol. 36:1992;209-215.
5. Chassande B., Leger J.M., Younes-Chennoufi A.B., Bengoufa D., Maisonobe T., Bouche P., Baumann N. Peripheral neuropathy associated with IgM monoclonal gammopathy: correlations between M-protein antibody activity and clinical and electrophysiological features in 40 cases. Muscle Nerve. 21:1998;55-62.
6. Chou D.K.H., Ilyas A.A., Evans J.E., Costello C., Quarles R.H., Jungawala F.B. Structure of sulfated glucuronyl glycolipids in the nervous system reacting with HNK-1 antibody and some IgM paraproteins in neuropathy. J. Biol. Chem. 261:1986;11717-11725.
7. Dalakas M.C., Quarles R.H. Autoimmune ataxic neuropathies (sensory ganglionopathies): are glycolipids the responsible autoantigens? Ann. Neurol. 39:1996;419-422.
8. Dalakas M.C., Quarles R.H., Farrer R.G., Dambrosia J., Shawke S., Stein D.P., Cupler E., Sekul E.A., Otero C. A controlled study of intravenous immunoglobulin in demyelinating neuropathy with IgM gammopathy. Ann. Neurol. 40:1996;792-795.
9. Graus F., Bonaventura I., Uchuya M., Valls-Sole J., Rene R., Leger J.M., Tolosa E., Delattre J.Y. Indolent anti-Hu-associated paraneoplastic syndrome. Neurology. 44:1994;2258-2261.
10. Hammer J.A., O'Shannessy D.J., De Leon M., Gould R., Zand D., Daune G., Quarles R.H. Immunoreactivity of PMP-22, P0 and other 19 to 28 kDa glycoproteins in peripheral nerve myelin of mammals and fish with HNK1 and related antibodies. J. Neurosci. Res. 35:1993;546-558.
11. Hass D.C., Tatum A.H. Plasmapheresis alleviates neuropathy accompanying IgM anti-myelin associated glycoprotein paraproteinemia. Ann. Neurol. 23:1988;394-396.
12. Hays A.P., Latov N., Takatsu M., Sherman W.H. Experimental myelination of nerve induced by serum of patients with neuropathy and anti-MAG M-proteins. Neurology. 37:1987;242-256.
13. Hays A.P., Lee S.S.L., Latov N. Immunoreactive C3d on the surface of myelin sheaths in neuropathy. J. Neuroimmunol. 18:1988;231-244.
14. Johnson D., Sato S., Quarles R.H., Inuzuka T., Brady R.O., Tourtellotte W.W. Quantitation of myelin-associated glycoprotein in human nervous tissue from controls and multiple sclerosis patients. J. Neurochem. 46:1986;1086-1093.
15. Ilyas A.A., Dalakas M.C., Brady R.O., Quarles R.H. Sulfated glucuronyl glycolipids reacting with anti-myelin-associated glycoprotein monoclonal antibodies including IgM paraprotein in neuropathy: species distribution and partial characterization of epitopes. Brain Res. 385:1986;1-9.
16. Ilyas A.A., Chou D.K.H., Jungalwala F.B., Costello C., Quarles R.H. Variability in the structural requirements for binding of human monoclonal anti-myelin-associated glycoprotein immunoglobulin M antibodies and HNK-1 to sphingoglycolipid antigens. J. Neurochem. 55:1990;594-601.
17. Ilyas A.A., Cook S.D., Dalakas M.C., Mithern F.A. Anti-MAG IgM paraproteins from some patients with polyneuropathy associated with IgM paraproteinemia also react with sulfatide. J. Neuroimmunol. 37:1992;85-92.
18. Kanda T., Yoshino H., Ariga T., Yamawaki M., Yu R.K. Glycosphingolipid antigens in cultured bovine brain microvascular endothelial cells: sulfoglucuronosyl paragloboside as a target of monoclonal IgM in demyelinative neuropathy. J. Cell. Biol. 126:1994;235-246.
19. Kohriyama T., Kusunoki S., Ariga T., Yoshino J.E., DeVries G.H., Latov N., Yu R.K. Subcellular localization of sulfated glucuronic acid-containing glycolipids reacting with anti-myelin associated glycoprotein antibody. J. Neurochem. 48:1987;1516-1522.
20. Kusunoki S., Kohriyama T., Pachner A.R., Latov N., Yu R.K. Neuropathy and IgM paraproteinemia: differential binding of IgM M-proteins to peripheral nerve glycolipids. Neurology. 37:1987;1795-1797.
21. Kusunoki S., Shimizu J., Chiba A., Ugawa Y., Hitoshi S., Kanazawa I. Experimental sensory neuropathy induced by sensitization with ganglioside GD1b. Ann. Neurol. 39:1996;424-431.
22. Latov N. Pathogenesis and therapy of neuropathies associated with monoclonal gammopathies. Ann. Neurol. 37:1995;S32-S42.
23. Ledeen R.W., Yu R.K., Eng L.F. Gangliosides of human myelin: sialosylgalactosyl-ceramide (G7) as a major component. J. Neurochem. 21:1973;829-839.
24. Lieberman F., Marton L., Stefansson K. Patterns of reactivity of IgM from the sera of eight patients with IgM monoclonal gammopathy and neuropathy with components of neural tissue: evidence for interaction with more than one epitope. Acta Neuropathol. 68:1985;196-200.
25. Meier C., Roberts K., Steck A., Hess C., Miloni E., Tschopp L. Polyneuropathy in Waldenstrom's macroglobulinemia: reduction of endoneurial IgM deposits after treatment with chlorambucil and plasmapheresis. Acta Neuropathol. (Berlin). 64:1984;297-307.
26. Monaco S., Bonetti B., Ferrari S., Moretto G., Nardelli E., Tedesco F., Mollnes T.E., Nobile-Orazio E., Manfredini E., Bonazzi L., Rizzuto N. Complement dependent demyelination in patients with IgM monoclonal gammopathy and monoclonal gammopathy and polyneuropathy. N. Engl. J. Med. 322:1990;844-852.
27. Monaco S., Ferrari S., Bonetti B., Moretto G., Kirshfink M., Nardelli E., Nobile-Orazio E., Zanusso G., Rizzuto N., Tedesco F. Experimental induction of myelin changes by anti-MAG antibodies and terminal complement complex. J. Neuropathol. Exp. Neurol. 54:1995;96-104.
28. Nobile-Orazio E., Baldini L., Barbieri S., Marmiroli P., Spagnol G., Francomano E., Scarlato G. Treatment of patients with neuropathy and anti-MAG IgM M-proteins. Ann. Neurol. 24:1988;93-97.
29. Norton W.T., Poduslo S.E. Myelination in rat brain: method of myelin isolation. J. Neurochem. 21:1973;749-757.
30. Pestronk A., Li F., Griffin J., Feldman E.L., Cornblath D., Trotter J., Zhu S., Yee W.C., Phillips D., Peeples D.M., Winslow B. Polyneuropathy syndromes associated with serum antibodies to sulfatide and myelin-associated glycoprotein. Neurology. 41:1991;357-362.
31. Poltorak M., Sadoul R., Keilhauer G., Landa C., Fahrig T., Schachner M. Myelin-associated glycoprotein, a member of the L2/HNK-1 family of neural cell adhesion molecules, is involved in neuron-oligodendrocyte and oligodendrocyte-oligodendrocyte interaction. J. Cell. Biol. 105:1987;1893-1899.
32. Quarles R.H. Human monoclonal antibodies associated with neuropathy. Meth. Enzymol. 179:1989;291-299.
33. Quarles R.H. The spectrum and pathogenesis of antibody-mediated neuropathies. Neuroscientist. 3:1997;95-204.
34. Schachner M., Martini R. Glycans and the modulation of neural-recognition molecule function. Trends Neurosci. 18:1995;183-191.
35. Snipes G.J., Suter U., Shooter E.M. Human peripheral myelin protein-22 carries the L2/HNK-1 carbohydrate adhesion epitope. J. Neurochem. 61:1993;1961-1964.
36. Takatsu M., Hays A.P., Latov N., Abrams G.M., Sherman W.H., Nemni R., Nobile-Orazio E., Saito T. Immunofluorescence studies of patients with neuropathy and 181 patients with neuropathy and IgM M-proteins. Ann. Neurol. 181:1985;173-181.
37. Tatum A.H. Experimental paraprotein neuropathy: demyelination by passive transfer of human IgM anti-myelin-associated glycoprotein. Ann. Neurol. 33:1993;502-506.
38. Tucker G.C., Dellagi K., Schmitt C., Brouet J.-C., Thiery J.P. Heterogeneity of human MAG IgM as revealed by their reactivity on avian embryonic tissues. Clin. Exp. Immunol. 67:1987;352-361.
39. Trojaborg W., Hays A.P., Van Der Berg L., Younger D.S., Latov N. Motor conduction parameters in neuropathies associated with anti-MAG antibodies and other types of demyelinating and axonal neuropathies. Muscle Nerve. 18:1995;730-735.
40. Uyemura, K., Kitamura, K., 1991. Comparative studies on myelin proteins in mammalian peripheral nerve. Comp. Biochem. Physiol., 9863-72.
41. Van den Berg L., Sadiq S.A., Thomas F.P., Latov N. Characterization of HNK-1 bearing glycoproteins in human peripheral nerve myelin. J. Neurosci. Res. 25:1990;295-299.
42. Van Der Berg L.H., Hays A.P., Nobile-Orazio E., Kinsella L.J., Manfredini E., Corbo M., Rosoklija G., Younger D.S., Lovelace R.E., Trojaborg W., Lange D.E., Goldstein S., Delfiner J., Sadiq S.A., Sherman W.H., Latov N. Anti-MAG and anti-SGPG antibodies in neuropathy. Muscle Nerve. 19:1996;637-643.
43. Volshol H., van Zuylen C.W.E.M., Orberger G., Vliegenthart J.F.G., Schachner M. Structure of the HNK-1 carbohydrate epitope on bovine peripheral myelin glycoprotein P0. J. Biol. Chem. 271:1996;22957-22960.
44. Weiss, M., Dalakas, M., Willison, H., Quarles, R., 1997. Variability in the binding of monoclonal IgM anti-MAG/SGPG antibodies from neuropathy patients to nerve glycoconjugates. J. Neurochem., 69S, S91A.
45. Willison H.J., Trapp B.D., Bacher J.D., Dalakas M.C., Griffin J.W., Quarles R.H. Demyelination induced by intraneural injection of human anti-myelin-associated glycoprotein antibodies. Muscle Nerve. 11:1988;1169-1176.