Isolation and characterization of four type-1 ribosome-inactivating proteins, with polynucleotide:adenosine glycosidase activity, from leaves of Phytolacca dioica L.

Planta

Volumn 208, Issue 1, 1999, Pages 125-131

  Di Maro, Antimo ^a   Valbonesi, Paola ^b   Bolognesi, Andrea ^b   Stirpe, Fiorenzo ^b   De Luca, Paolo ^c   Gigliano, Gesualdo Siaiscalco ^c   Gaudio, Luciano ^d   Delli Bovi, Pasquale ^d   Ferranti, Pasquale ^e   Malorni, Antonio ^e   Parente, Augusto ^a  

^a Dipartimento di Scienze della Vita   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c Dipartimento di Biologia Vegetale   (Italy)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^e ICMIB   (Italy)

Author keywords

Phytolacca; Polynucleotide:adenosine glycosidase; Ribosome inactivating protein

Indexed keywords

AMINO ACID SEQUENCE; ELECTROSPRAY MASS SPECTROMETRY; ENZYME KINETICS; ENZYME PURIFICATION; ISOELECTRIC POINT; MASS SPECTROMETRY; POLYNUCLEOTIDE ADENOSINE GLYCOSIDASE; PROTEIN ANALYSIS; PROTEIN ISOLATION; RIBOSOME; SDS POLYACRYLAMIDE GEL ELECTROPHORESIS;

AMINO ACID SEQUENCE; CHROMATOGRAPHY, ION EXCHANGE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MOLECULAR SEQUENCE DATA; N-GLYCOSYL HYDROLASES; PLANT LEAVES; PLANT PROTEINS; PROTEIN CONFORMATION; RIBOSOMES; SEQUENCE HOMOLOGY, AMINO ACID; TREES;

CLUPEA HARENGUS; ORYCTOLAGUS CUNICULUS; PHYTOLACCA; PHYTOLACCA AMERICANA; PHYTOLACCA DIOICA; PHYTOLACCACEAE;

EID: 0033103581     PISSN: 00320935     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004250050542     Document Type: Article

References (48)

1. Barbieri L, Battelli MG, Stirpe F (1993) Ribosome-inactivating proteins from plants. Biochim Biophys Acta 1154: 237-282
2. Barbieri L, Gorini P, Valbonesi P, Castiglioni P, Stirpe F (1994) Unexpected activity of saporins. Nature 372: 624
3. Barbieri L, Valbonesi P, Gorini P, Pession A, Stirpe F (1996) Polynucleotide: adenosine glycosidase activity of saporin L-I: effect on DNA, RNA and poly(A). Biochem J 319: 507-513
4. Barbieri L, Valbonesi P, Bonora E, Gorini P, Bolognesi A, Stirpe F (1997) Polynucleotide: adenosine glycosidase activity of ribosome-inactivating proteins: effect on DNA, RNA and poly(A). Nucleic Acids Res 25: 518-522
5. Bolognesi A, Tazzari PL, Olivieri F, Polito L, Falini B, Stirpe F (1996) Induction of apoptosis by ribosome-inactivating proteins and related immunotoxins. Int J Cancer 68: 349-355
6. Citores L, de Benito FM, Iglesias R, Ferreras JM, Argueso P, Zimenez P, Testera A, Camafeita E, Méndez E, Girbés T (1997) Characterization of a new non-toxic two-chain ribosome-inactivating protein and a structurally related lectin from rhizomes of dwarf elder (Sambucus ebulus L.). Cell Mol Biol 43: 485-499
7. de Benito FM, Citores L, Iglesias R, Ferreras JM, Camafeita E, Méndez E, Girbés T (1997) Isolation and partial characterization of a novel and uncommon two-chain 64-kDa ribosomeinactivating protein from the bark of elder (Sambucus nigra). FEBS Lett 413: 85-91
8. De Falco G (1992) Isolamento e caratterizzazione di proteine inattivanti i ribosomi da foglie di Phytolacca dioica L. Thesis dissertation, University of Naples, Federico II (in Italian)
9. Del Vecchio Blanco F, Bolognesi A, Malorni A, Sande MJW, Savino G, Parente A (1997) Complete amino acid sequence of PD-S2, a new ribosome-inactivating protein from seeds of Phytolacca dioica L. Biochim Biophys Acta 1338: 137-144
10. Duggar BM, Armstrong JK (1925) The effect of treating the virus of tobacco mosaic with the juices of various plants. Ann Mo Bot Gard 12: 359-366
11. Endo Y (1988) Mechanism of action of ricin and related toxins on the inactivation of eukaryotic ribosomes. In: Frankel AE (ed), Immunotoxins. Kluwer, Boston, pp 75-89
12. Endo Y, Tsurugi K (1987) RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes. J Biol Chem 262: 8128-8130
13. Endo Y, Tsurugi K, Ebert RF (1988) The mechanism of action of barley toxin: a type 1 ribosome-inactivating protein with RNA N-glycosidase activity. Biochim Biophys Acta 954: 224-226
14. Ferreras JM, Barbieri L, Girbés T, Battelli MG, Rojo MA, Arias FJ, Rocher MA, Soriano F, Méndez E, Stirpe F (1993) Distribution and properties of major ribosome-inactivating proteins (28 S rRNA N-glycosidases) of the plant Saponaria officinalis L. (Caryophyllaceae). Biochim Biophys Acta 1216: 31-42
15. Girbés T, Citores L, Iglesias R, Ferreras JM, Muñoz R, Rojo MA, Arias FJ, Garcia JR, Méndez E, Calonge M (1993a) Ebulin-1, a nontoxic novel type 2 ribosome-inactivating protein from Sambucus ebulus L. leaves. J Biol Chem 268: 18195-18199
16. Girbés T, Citores L, Ferreras JM, Rojo MA, Iglesias R, Muñoz R, Arias FJ, Calonge M, Garcia JR, Méndez E (1993b) Isolation and partial characterization of nigrin b, a non-toxic novel type-2 ribosome-inactivating protein from the bark of Sambucus nigra L. Plant Mol Biol 22: 1181-1186
17. Go TTM, Yeung HW, Fong WP (1992) Deoxyribonucleolytic activity of α-and β-momorcharins. Life Sci 51: 1347-1353
18. Hong Y, Saunders K, Hartley MR, Stanley J (1996) Resistance to geminivirus infection by virus-induced expression of dianthin in transgenic plants. Virology 220: 119-127
19. Jach G, Görnhardt B, Mundy J, Logemann J, Pinsdorf E, Leah R, Schell J, Mass C (1995) Enhanced quantitative resistance against disease by combinatorial expression of different barley antifungal proteins in transgenic tobacco. Plant J 8: 97-109
20. Lam YH, Wong YS, Wang B, Wong RNS, Yeung HW, Shaw PC (1996) Use of trichosantin to reduce infection by turnip mosaic virus. Plant Sci 114: 111-117
21. Li M-X, Yeuang H-W, Pan L-P, Chan S-I (1991) Trichosantin, a potent HIV-1 inhibitor, can cleave supercoiled DNA in vitro. Nucleic Acids Res 22: 6309-6312
22. Ling J, Liu W-Y, Wang TP (1994) Cleavage of supercoiled double-stranded DNA by several ribosome-inactivating proteins in vitro. FEBS Lett 345: 143-146
23. Lodge JK, Kaniewski WK, Turner NE (1993) Broad-spectrum virus resistance in transgenic plants expressing pokeweed antiviral protein. Proc Natl Acad Sci USA 90: 7089-7093
24. Massiah AJ, Hartley MR (1995) Wheat ribosome-inactivating proteins: seed and leaf forms with different specificities and cofactor requirements. Planta 197: 633-640
25. McCann WP, Hall LM, Nonidez WK (1983) Preparation, titration, and storage of chloroacetaldehyde for fluorometric determination of adenine and its derivatives. Anal Chem 55: 1455-1456
26. McCann WP, Hall LM, Siler W, Barton N, Whitley RJ (1985) High pressure liquid chromatographic methods for determining arabinosyladenine-5-monophosphate, arabinosyl adenine and arabinosylhypoxanthine in plasma and urine. Antimicrob Agents Chemother 28: 265-273
27. Moon YH, Jeon HS, Choi KW, Lee JS (1994) Development of virus-resistant potato by expression of Phytolacca antiviral protein. Mol Cells 4: 183-188
28. Moon YH, Song S-K, Choi KW, Lee JS (1997) Expression of a cDNA encoding Phytolacca insularis antiviral protein confers virus resistance on transgenic potato plants. Mol Cells 7: 807-815
29. Nicolas E, Beggs JM, Haltiwanger BM, Taraschi TF (1997a) Direct evidence for the deoxyribonuclease activity of the plant ribosome-inactivating protein gelonin. FEBS Lett 406, 162-164
30. Nicolas E, Goodyer ID, Taraschi TF (1997b) An additional mechanism of ribosome-inactivating protein cytotoxicity: degradation of extrachromosomal DNA. Biochem J 327: 413-417
31. Nicolas E, Beggs JM, Haltiwanger BM, Taraschi TF (1998) A new class of DNA glycosylase/apurinic/apyrimidinic lyases that act on specific adenines in single-stranded DNA. J Biol Chem 273: 17216-17220
32. Obrig TG, Irvin JD, Hardesty B (1973) The effect of an antiviral peptide on the ribosomal reactions of the peptide elongation enzymes-EF-I and EF-II. Arch Biochem Biophys 155: 278-289
33. Parente A, de Luca P, Bolognesi A, Barbieri L, Battelli MG, Abbondanza A, Sande MJW, Siniscalco Gigliano G, Tazzari PL, Stirpe F (1993) Purification and partial characterization of single-chain ribosome-inactivating proteins from the seeds of Phytolacca dioica L. Biochim Biophys Acta 1216: 43-49
34. Pu Z, Lu BY, Liu WY, Jin SW (1997) Characterization of the enzymatic mechanism of γ-momorcharin, a novel ribosome-inactivating protein with lower molecular weight of 11500 purified from the seeds of bitter gourd (Momordica charantia). Biochem Biophys Res Commun 229: 287-294
35. Robertson EF, Dannelly HK, Malloy PJ, Reeves HC (1987) Rapid isoelectric focusing in a vertical polyacrylamide minigel system. Anal Biochem 167: 290-294
36. Rojo MA, Yato M, Ishii-Minami N, Minami E, Kaku H, Citores L, Girbés T, Shibuya N (1997) Isolation, cDNA cloning, biological properties, and carbohydrate binding specificity of sieboldin-b, a type II ribosome-inactivating protein from the bark of Japanese elderberry (Sambucus sieboldiana). Arch Biochem Biophys 340: 185-194
37. Roncuzzi L, Gasperi-Campani A (1996) DNA-nuclease activity of the single-chain ribosome-inactivating proteins dianthin 30, saporin 6 and gelonin, FEBS Lett 392: 16-20
38. Smirnov S, Shulaev V, Tumer NE (1997) Expression of pokeweed antiviral protein in transgenic plants induces virus resistance in grafted wild-type plants independently of salicylic acid accumulation and pathogenesis-related protein synthesis. Plant Physiol 114: 1113-1121
39. Stillmark H (1888) Ueber Ricin, ein giftiges Ferment aus den Samen von Ricinus comm L. und einigen anderen Euphorbiaceen. Inaugural Dissertation, Dorpat
40. Stirpe F, Williams DG, Onyon LJ, Legg RF, Stevens WA (1981) Dianthins, ribosome-damaging proteins with anti-viral properties from Dianthus caryophyllus L. (carnation). Biochem J 195: 399-405
41. Stirpe F, Bailey S, Miller SP, Bodley JW (1988) Modification of ribosomal RNA by ribosome-inactivating proteins from plants. Nucleic Acid Res 16: 1349-1357
42. Tanigawa M, Yamagami T, Funatsu G (1995) The complete amino acid sequence of chitinase-B from the leaves of pokeweed (Phytolacca americana). Biosci Biotechnol Biochem 5: 841-847
43. Terawaki K, Nose M, Kondo T, Kojima K, Mizukama H, Ogihara Y (1997) Effect of karasurin-A on nitric oxide production by murine macrophages and mitogenic response of murine splenocytes in vitro. Biol Phamacol Bull 20: 435-437
44. Van Damme EJM, Barre A, Barbieri L, Valbonesi P, Rougé P, Van Leuven F, Stirpe F, Peumans WJ (1997a) Type-I ribosome-inactivating proteins are the most abundant proteins in iris (Iris hollandica var Professor Blaauw) bulbs: characterization and molecular cloning. Biochem J 324: 963-970
45. Van Damme EJM, Barre A, Rougé P, Van Leuven F, Peumans WJ (1997b) Isolation and molecular cloning of a novel type-2 ribosome-inactivating protein with an inactive B chain from elderberry (Sambucus nigra) bark. J Biol Chem 272: 8353-8360
46. Walsh TA, Morgan AE, Hey TD (1991) Characterization and molecular cloning of a proenzyme form of a ribosome-inactivating protein from maize. Novel mechanism of proenzyme activation by proteolytic removal of a 2.8-kilodalton internal peptide segment. J Biol Chem 266: 23422-23427
47. Williams JM, Lea N, Lord JM, Roberts JM, Milford DV, Taylor CV (1997) Comparison of ribosome-inactivating proteins in the induction of apoptosis. Toxicol Lett 91: 121-127
48. Zamboni M, Brigotti M, Rambelli F, Montanaro L, Sperti S (1989) High pressure liquid chromatographic and fluorimetric methods for the determination of adenine released from ribosomes by ricin and gelonin. Biochem J 259: 639-643