Vernier zone residue 4 of mouse subgroup II kappa light chains is a critical determinant for antigen recognition

Immunotechnology

Volumn 4, Issue 3-4, 1999, Pages 203-215

  De Haard, Hans ^a   Kazemier, Bert ^a   Van der Bent, Arie ^b   Oudshoorn, Peter ^a   Boender, Piet ^a   Arends, Jan Willem ^c,d   Van Gemen, Bob ^a  

^a Bioscience Research Unit   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^d MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Antigen binding; Bacterial expression; Folding; Frame work residue; Single chain antibody; Vernier zone

Indexed keywords

IMMUNOGLOBULIN KAPPA CHAIN;

ANTIBODY STRUCTURE; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; GENE MUTATION; IMMUNOGLOBULIN STRUCTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY REACTIONS; CHORIONIC GONADOTROPIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION; PROTEIN FOLDING; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033103560     PISSN: 13802933     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1380-2933(98)00021-9     Document Type: Article

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