CagA and cytotoxicity of Helicobacter pylori are not markers of peptic ulcer in Japanese patients

Helicobacter

Volumn 4, Issue 1, 1999, Pages 1-6

  Tokumaru, Kenkichi ^a   Kimura, Ken ^a   Saifuku, Kouji ^a   Kojima, Toshichika ^a   Satoh, Kiichi ^a   Kihira, Ken ^a   Ido, Kenichi ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL DNA; BACTERIAL PROTEIN; BIOLOGICAL MARKER; CAGA PROTEIN, HELICOBACTER PYLORI; CYTOTOXIN; VACA PROTEIN, HELICOBACTER PYLORI;

ADOLESCENT; ADULT; AGED; ARTICLE; BIOPSY; CELL DIVISION; CHILD; CHRONIC DISEASE; CLASSIFICATION; DRUG EFFECT; FEMALE; GASTRITIS; GENE FREQUENCY; GENETICS; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; MALE; MICROBIOLOGY; MIDDLE AGED; PATHOGENICITY; PATHOLOGY; PEPTIC ULCER; SPECIES DIFFERENCE; STOMACH MUCOSA;

ADOLESCENT; ADULT; AGED; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BIOLOGICAL MARKERS; BIOPSY; CELL DIVISION; CHILD; CHRONIC DISEASE; CYTOTOXINS; DNA, BACTERIAL; FEMALE; GASTRIC MUCOSA; GASTRITIS; GENE FREQUENCY; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MIDDLE AGED; PEPTIC ULCER; SPECIES SPECIFICITY;

EID: 0033085429     PISSN: 10834389     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-5378.1999.09003.x     Document Type: Article

References (4)

1. Figura N, Guglielmetti P, Rossolini A, Barberi A, Cusi G, Musmanno RA, Russi M, Quaranta S. Cytotoxin production by Campylobacter pylori strains isolated from patients with peptic ulcers and from patients with chronic gastritis only. J Clin Microbiol 1989;27:225-6.
2. Covacci A, Censini S, Bugnoli M, et al. Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci USA 1993;90:5791-5.
3. Labigne A, Lamouliatte H, Birac C, Sedaillian A, Megraud F. Distribution of the cagA gene among Helicobacter pylori strains associated with peptic ulcer. Am J Gastroenterol 1994;89:1526.
4. Atherton JC, Cao P, Peek RM, Tummuru MK, Blaser MJ, Cover TL. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori: association of specific vacA types with cytotoxin production and peptic ulceration. J Biol Chem 1995;270:17771-7.