13N-ammonia myocardial blood flow and uptake: Relation to functional outcome of asynergic regions after revascularization

Journal of the American College of Cardiology

Volumn 33, Issue 3, 1999, Pages 678-686

  Kitsiou, Anastasia N ^a,b   Bacharach, Stephen L ^a,b   Bartlett, Marissa L ^a,b   Srinivasan, Gopal ^a,b   Summers, Ronald M ^a,b   Quyyumi, Arshed A ^a,b   Dilsizian, Vasken ^a,b  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA N 13; FLUORODEOXYGLUCOSE F 18; RADIOPHARMACEUTICAL AGENT; THALLIUM; UNCLASSIFIED DRUG; AMMONIA; DIAGNOSTIC AGENT; NITROGEN;

ADULT; AGED; ARTICLE; CELL VIABILITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE COURSE; FEMALE; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE BLOOD FLOW; HEART MUSCLE CELL; HEART MUSCLE REVASCULARIZATION; HEART SCINTISCANNING; HEART VENTRICLE WALL MOTION; HUMAN; INTERMETHOD COMPARISON; INTRAVENOUS DRUG ADMINISTRATION; MALE; POSITRON EMISSION TOMOGRAPHY; PREDICTION; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TREATMENT OUTCOME; BLOOD FLOW VELOCITY; COMPARATIVE STUDY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CORONARY ARTERY BLOOD FLOW; GATED IMAGING; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; HEART VENTRICLE; METABOLISM; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; ROC CURVE; SCINTISCANNING;

ADULT; AGED; AMMONIA; BLOOD FLOW VELOCITY; CORONARY CIRCULATION; CORONARY DISEASE; FEMALE; FLUORODEOXYGLUCOSE F18; GATED BLOOD-POOL IMAGING; HEART VENTRICLES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MYOCARDIAL REVASCULARIZATION; NITROGEN RADIOISOTOPES; ROC CURVE; STROKE VOLUME; THALLIUM RADIOISOTOPES; TOMOGRAPHY, EMISSION-COMPUTED; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TREATMENT OUTCOME; VENTRICULAR DYSFUNCTION, LEFT;

EID: 0033084216     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(98)00630-5     Document Type: Article

References (33)

1. Rahimtoola S.H. Coronary bypass surgery for chronic angina - 1981 a perspective . Circulation. 65:1982;225-241.
2. Braunwald E., Rutherford J.D. Reversible ischemic left ventricular dysfunction: evidence for the "hibernating myocardium" J Am Coll Cardiol. 8:1986;1467-1470.
3. 3 myocardial extraction and clearance on flow and metabolism. Am J Physiol. 242:1982;H536-H542.
4. 3 by myocardium on metabolic factors and its implications for quantitative assessment of perfusion. Circulation. 61:1980;34-43.
5. Schelbert H.R., Phelps M.E., Huang S.-C., et al. N-13 ammonia as an indicator of myocardial blood flow. Circulation. 63:1981;1259-1272.
6. 18F-labeled fluorodeoxyglucose and N-13 ammonia. Circulation. 67:1983;766-778.
7. Hutchins G.D., Schwaiger M., Rosenspire K.C., Krivokapich J., Schelbert H.R., Kuhl D.E. Noninvasive quantification of regional blood flow in the human heart using N-13 ammonia and dynamic positron emission tomographic imaging. J Am Coll Cardiol. 15:1990;1032-1042.
8. 13N-ammonia and reoriented dynamic positron emission tomographic imaging. Circulation. 86:1992;1004-1017.
9. Gewirtz H., Fischman A.J., Abraham S., Gilson M., Strauss H.W., Alpert N.M. Positron emission tomographic measurements of absolute regional myocardial blood flow permits identification of nonviable myocardium in patients with chronic myocardial infarction. J Am Coll Cardiol. 23:1994;851-859.
10. Tamaki N., Kawamoto M., Tadamura E., et al. Prediction of reversible ischemia after revascularization perfusion and metabolic studies with positron emission tomography . Circulation. 91:1995;1697-1705.
11. Klocke R.A., Anderson K.K., Rotman H.H., Forster R.E. Permeability of human erythrocytes to ammonia and weak acids. Am J Physiol. 222:1972;1004-1013.
12. Post R.L., Jolly P.C. The linkage of sodium, potassium and ammonium active transport across the human erythrocyte membrane. Biochim Biophys Acta. 25:1957;118-128.
13. Davidson S., Sonnenblick E.H. Glutamine production by the isolated perfused rat heart during ammonium chloride perfusion. Cardiovasc Res. 9:1975;295-301.
14. Duda G.D., Handler P. Kinetics of ammonia metabolism in vivo. J Biol Chem. 232:1958;303-314.
15. 13N-ammonia uptake in myocardial single cells indicating potential limitations in its applicability as a marker of myocardial blood flow. Circulation. 71:1985;387-393.
16. Dilsizian V., Rocco T.P., Friedman N.M.T., Leon M.B., Bonow R.O. Enhanced detection of ischemic but viable myocardium by the reinjection of thallium after stress-redistribution imaging. N Engl J Med. 323:1990;141-146.
17. 18F-fluorodeoxyglucose . Circulation. 83:1991;26-37.
18. Borer J.S., Bacharach S.L., Green M.V., Kent K.M., Epstein S.E., Johnston G.S. Real-time radionuclide cineangiography in the noninvasive evaluation of global and regional left ventricular function at rest and during exercise in patients with coronary-artery disease. N Engl J Med. 296:1977;839-844.
19. Czernin J., Muller P., Chan S., et al. Influence of age and hemodynamics on myocardial blood flow and flow reserve. Circulation. 88:1993;62-69.
20. Gewirtz H., Skopicki H.A., Abraham S.A., et al. Quantitative PET measurements of regional myocardial blood flow observations in humans with ischemic heart disease . Cardiology. 88:1997;62-70.
21. Beanlands R.S., deKemp R., Scheffel A., et al. Can nitrogen-13 ammonia kinetic modeling define myocardial viability independent of fluorine-18 fluorodeoxyglucose? J Am Coll Cardiol. 29:1997;537-543.
22. Gould L.K., Yoshida K., Hess M.J., Haynie M., Mullani N., Smalling R.W. Myocardial metabolism of fluorodeoxyglucose compared to cell membrane integrity for the potassium analogue rubidium-82 for assessing infarct size in man by PET. J Nucl Med. 32:1991;1-9.
23. Pohost G.M., Zir L.M., Moore R.H., McKusick K.A., Guiney T.E., Beller G.A. Differentiation of transiently ischemic from infarcted myocardium by serial imaging after a single dose of thallium-201. Circulation. 55:1977;294-302.
24. Goldhaber S.Z., Newell J.B., Alpert N.M., Andrews E., Pohost G.M., Ingwall J.S. Effects of ischemic-like insult on myocardial thallium-201 accumulation. Circulation. 67:1983;778-786.
25. Gewirtz H., Sullivan M.J., Shearer D.R., et al. Analysis of proposed mechanisms of thallium redistribution comparison of a computer model of myocardial thallium kinetics with quantitative analysis of clinical scans . IEEE Computers Cardiol. 8:1981;75-80.
26. Nelson C.W., Wilson R.A., Angello D.A., Palac R.T. Effect of thallium-201 blood levels on reversible thallium defects. J Nucl Med. 30:1989;1172-1175.
27. Dilsizian V., Bonow R.O. Differential uptake and apparent thallium-201 "washout" after thallium reinjection options regarding early redistribution imaging before reinjection or late redistribution imaging after reinjection . Circulation. 85:1992;1032-1038.
28. Tillisch J.H., Brunken R., Marshall R., et al. Reversibility of cardiac wall-motion abnormalities predicted by positron tomography. N Engl J Med. 314:1986;884-888.
29. vom Dahl J., Eitzman D.T., Al-Aouar Z.R., et al. Relation of regional function, perfusion, and metabolism in patients with advanced coronary artery disease undergoing surgical revascularization. Circulation. 90:1994;2356-2366.
30. 18F]2-deoxy-2-fluoro-d-glucose for assessing myocardial glucose uptake. Circulation. 91:1995;2435-2444.
31. Schwarz E.R., Schaper J., vom Dahl J., et al. Myocyte degeneration and cell death in hibernating human myocardium. J Am Coll Cardiol. 27:1996;1577-1585.
32. Kitsiou A.N., Srinivasan G., Quyyumi A.A., Summers R.M., Bacharach S.L., Dilsizian V. Stress-induced reversible and mild-to-moderate irreversible thallium defects are they equally accurate for predicting recovery of regional left ventricular function after revascularization? Circulation. 98:1998;501-508.
33. Dilsizian V. Myocardial viability contractile reserve or cell membrane integrity? J Am Coll Cardiol. 28:1996;443-446.