Detection of melatonin, its precursors and related enzyme activities in rabbit lens

Experimental Eye Research

Volumn 68, Issue 2, 1999, Pages 255-262

  Abe, Mitsushi ^a   Itoh, Masanori T ^b   Miyata, Mikio ^a   Ishikawa, Satoshi ^a   Sumi, Yawara ^b  

^a KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Hydroxyindole O methyltransferase; Lens; Melatonin; Serotonin; Serotonin N acetyltransferase

Indexed keywords

ACETYLSEROTONIN METHYLTRANSFERASE; MELATONIN; SEROTONIN; SEROTONIN N ACETYLTRANSFERASE; TRYPTOPHAN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; FEMALE; FLUOROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE DETERMINATION; LENS; LIGHT DARK CYCLE; MICHAELIS CONSTANT; NONHUMAN; PINEAL BODY; PRIORITY JOURNAL; RABBIT; RADIOIMMUNOASSAY;

EID: 0033083439     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1998.0601     Document Type: Article

References (34)

1. Abe, M., Reiter, R. J., Orhii, P. B., Hara, M. and Poeggeler, B. (1994). Inhibitory effect of melatonin on cataract formation in newborn rats: Evidence for an anti- oxidative role for melatonin. J. Pineal. Res. 17, 94-100.
2. Axelrod, J. (1974). The pineal gland: A neurochemical transducer. Science 184, 1341-8.
3. Besharse, J. C. and Dunis, D. A. (1983). Methoxyindoles and photoreceptor metabolism: Activation of rod shedding. Science 219, 1341-3.
4. Binkley, S. (1993). Structures and molecules involved in generation and regulation of biological rhythms in vertebrates and invertebrates. Experimentia 49, 648-53.
5. Binkley, S., Hryshchyshyn, M. and Reilly, K. (1979). N- Acetyltransferase activity responds to environmental lighting in the eye as well as in the pineal gland. Nature 281, 479-81.
6. Bradford, M. M. (1976). A rapid and sensitive method for the titration of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-54.
7. Brezezinski, A. (1997). Melatonin in humans. N. Engl. J. Med. 336, 186-95.
8. Cahill, G. M., Grace, M. S. and Besharse, J. C. (1991). Rhythmic regulation of retinal melatonin: Metabolic pathways, neurochemical mechanisms, and the ocular circadian clock. Cell. Mol. Neurobiol. 11, 529-60.
9. Cardinali, D. P. and Wurtman, R. J. (1972). Hydroxyindole- O-methyl transferases in rat pineal, retina and Harderian gland. Endocrinology 91, 247-52.
10. Dierce, M. E. and Besharse, J. C. (1985). Circadian regulation of retinomotor movement I. Interaction of melatonin and dopamine in the control of cone length. J. Gen. Physiol. 86, 671-89.
11. Djeridane, Y., Vivien-Roels, B., Simonneaux, V., Miguez, J. M., and Pevét, P. (1998). Evidence for melatonin synthesis in rodent harderian gland : A dynamic in vitro study. J. Pineal Res. 25, 54-64.
12. Dollins, A. B., Zhdanova, I. V., Wurtman, R. J., Lynch, H. J. and Deng, M. H. (1994). Effect of inducting nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance. Proc. Natl. Acad. Sci. USA 91, 1824-8.
13. Dubocovich, M. L. (1985). Characterization of a retinal melatonin receptor. J. Pharmacol. Exp. Ther. 234, 395-401.
14. Heim, M. H., Blumn, M., Beer, M. and Meyer, U. A. (1991). Acetylation of serotonin in the rabbit pineal gland: An N-acetyltransferase with properties distinct from NAT1 and NAT2 is responsible. J. Neurochem. 57, 1095-9.
15. Heuther, G. (1993). The contribution of extrapineal sites of melatonin synthesis to circulating melatonin levels in higher vertebrates. Experimentia 49, 665-70.
16. Itoh, M. T., Hattori, A., Nomura, T., Sumi, Y. and Suzuki, T. (1995). Melatonin and arylalkylamine N-acetyltransferase activity in the silkworm, Bombyx Mori. Mol. Cell. Endocrinol. 115, 59-64.
17. Itoh, M. T., Ishizuka, B., Kudo, Y., Fusama, S., Amemiya, A. and Sumi, Y. (1977a). Detection of melatonin and serotonin N-acetyltransferase and hydroxyindole-O- methyltransferase activities in rat ovary. Mol. Cell. Endocrinol. 136, 7-13.
18. Itoh, M. T., Hattori, A. and Sumi, Y. (1997b). Hydroxyindole-O-methyltransferase activity assay using high-performance liquid chromatography with fluorometric detection: Determination of melatonin enzymatically formed from N-acetylserotonin and S- Adenosyl-L-methionine. J. Chromatogr. B. 692, 217-21.
19. Lee Chin, J. R. (1992). Determination of the catecholamines and serotonin, their precursors tyrosine and tryptophan, and their main metabolites in rat brain using reversed-phase high-performance liquid chromatography with fluorimetric and oxidative amperometric detection in series. J. Chromatogr. 578, 17-30.
20. Li, Z. R., Reiter, R. J., Fujimori, O., Oh, C. S. and Duan, Y. P. (1997). Cataractgenesis and lipid peroxidation in newborn rats treated with buthionine sulfoximine: Preventive actions of melatonin. J. Pineal Res. 22, 117-23.
21. Namboodiri, M. A. A., Dubbels, R. and Klein, D. C. (1987). Arylalkylamine N-acetyltransferase from mammalian pineal gland. Methods Enzymol. 142, 583-90.
22. Osborne, N. N., Chidlow, G. (1994). The presence of functional melatonin receptors in the iris-ciliary processes of the rabbit eye. Exp. Eye. Res. 59, 3-9.
23. Pang, S. F., Yu, H. S., Suen, H. C. and Brown, G. M. (1980). Melatonin in the retina of rats: A diurnal rhythm. J. Endocr. 87, 89-93.
24. Quay, W. B. (1965). Retinal and pineal hydroxyindole-O- methyltransferase activity in vertebrates. Life Sci. 4, 983-91.
25. Reiter, R. J. (1993). The melatonin rhythm: Both a clock and a calendar. Experimentia 49, 654-64.
26. Reiter, R. J., Carneiro, R. C. and Oh, C. S. (1997a). Melatonin in relation to cellular antioxidative defense mechanisms. Horm. Metab. Res. 29, 363-72.
27. Reiter, R. J., Tang, J., Garcia, J. J. and Huñoz-Hoyos, A. (1997b). Pharmacological actions of melatonin in oxygen radical pathophysiology. Life Sci. 60, 2255-71.
28. Rohde, B. H., McLaughlin, M. A. and Chiou, L. Y. (1985). Existence and role of endogenous ocular melatonin. J. Ocular. Pharmacol. 1, 235-343
29. Sugden, D., Ceña, V. and Klein, D. C. (1987). Hydroxyindole- O-methyltransferase. Methods Enzymol. 142, 590-6.
30. Tarmarkin, L., Baird, C. J. and Almeida, O. F. X. (1985). Melatonin: A coordinating signal for mammalian reproduction? Science 227, 714-20.
31. Tosini, G. and Menaker, M. (1996). Circadian rhythms in cultured mammalian retina. Science 272, 419-21.
32. Vaugham, G. M. (1993). New sensitive serum melatonin radioimmunoassay employing the Kennaway G280 antibody: Syrian hamster morning adrenergic response. J. Pineal Res. 15, 88-103.
33. Voisin, P., Namboodiri, M. A. A. and Klein, D. C. (1984). Arylamine N-acetyltransferase and arylalkylamine N- Acetyltransferase in the mammalian pineal gland. J. Biol. Chem. 259, 10913-18.
34. Yu, H. S., Yee, R. W., Howes, K. A. and Reiter, R. J. (1990). Diurnal rhythms of immunoreactive melatonin in the aqueous humor and serum of male pigmented rabbits. Neurosci. Lett. 116, 309-14.