메뉴 건너뛰기




Volumn 267, Issue 1, 1999, Pages 24-29

Quantification of ribonucleotide reductase expression in wild-type and hydroxyurea-resistant cell lines employing in situ reverse transcriptase polymerase chain reaction and a computerized image analysis system

Author keywords

Drug resistance; Gene expression; Hydroxyurea; In situ RT PCR; Ribonucleotide reductase

Indexed keywords

CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; FREE RADICALS; GENE EXPRESSION; GROWTH KINETICS; IMAGE ANALYSIS; TRANSCRIPTION;

EID: 0033080769     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.1998.2890     Document Type: Article
Times cited : (5)

References (21)
  • 1
    • 0032562720 scopus 로고    scopus 로고
    • Visualization of single RNA transcripts in situ
    • Femino A. M., Fay F. S., Fogarty K., Singer R. H. Visualization of single RNA transcripts in situ. Science. 280:1998;585-590.
    • (1998) Science , vol.280 , pp. 585-590
    • Femino, A.M.1    Fay, F.S.2    Fogarty, K.3    Singer, R.H.4
  • 2
    • 0027473615 scopus 로고
    • Human immunodeficiency virus type I provirus is demonstrated in peripheral blood monocytes in vivo: A study utilizing an in situ polymerase chain reaction
    • Bagasra O., Pomerantz R. J. Human immunodeficiency virus type I provirus is demonstrated in peripheral blood monocytes in vivo: A study utilizing an in situ polymerase chain reaction. AIDS Res. Hum. Retroviruses. 9:1993;69-76.
    • (1993) AIDS Res. Hum. Retroviruses , vol.9 , pp. 69-76
    • Bagasra, O.1    Pomerantz, R.J.2
  • 3
    • 0028796668 scopus 로고
    • In situ DNA PCR and DNA hybridization detection of herpes simplex virus sequences in trigeminal ganglia of latently infected mice
    • Mehta A., Maggioncalda J., Bagasra O., Thikkavarapu S., Saikumari P., Valyi-Nagy T., Fraser N. W., Block T. R. In situ DNA PCR and DNA hybridization detection of herpes simplex virus sequences in trigeminal ganglia of latently infected mice. Virology. 206:1995;633-640.
    • (1995) Virology , vol.206 , pp. 633-640
    • Mehta, A.1    Maggioncalda, J.2    Bagasra, O.3    Thikkavarapu, S.4    Saikumari, P.5    Valyi-Nagy, T.6    Fraser, N.W.7    Block, T.R.8
  • 4
    • 0026510316 scopus 로고
    • Detection of human immunodeficiency virus type I provirus in mononuclear cells by in situ polymerase chain reaction
    • Bagasra O., Hauptman S. P., Lisohner H. W., Sachs M., Pomerantz R. J. Detection of human immunodeficiency virus type I provirus in mononuclear cells by in situ polymerase chain reaction. N. Engl. J. Med. 326:1992;1385-1391.
    • (1992) N. Engl. J. Med. , vol.326 , pp. 1385-1391
    • Bagasra, O.1    Hauptman, S.P.2    Lisohner, H.W.3    Sachs, M.4    Pomerantz, R.J.5
  • 6
    • 0025993916 scopus 로고
    • Detection of human papillomavirus DNA in formalin fixed tissues by in situ hybridization after PCR
    • Nuovo G. J., MacConnell P., Forde A. Detection of human papillomavirus DNA in formalin fixed tissues by in situ hybridization after PCR. Am. J. Pathol. 139:1991;847-854.
    • (1991) Am. J. Pathol. , vol.139 , pp. 847-854
    • Nuovo, G.J.1    MacConnell, P.2    Forde, A.3
  • 7
    • 0344490886 scopus 로고    scopus 로고
    • Micropreparation of cultured cells forin situ
    • Zhang H., Wadler S. Micropreparation of cultured cells forin situ. Biotechniques. 22:1997;619-624.
    • (1997) Biotechniques , vol.22 , pp. 619-624
    • Zhang, H.1    Wadler, S.2
  • 8
    • 0025214461 scopus 로고
    • Ribonucleotide reductases: Amazing and confusing
    • Stubbe J. Ribonucleotide reductases: Amazing and confusing. J. Biol. Chem. 265:1990;5329-5332.
    • (1990) J. Biol. Chem. , vol.265 , pp. 5329-5332
    • Stubbe, J.1
  • 9
    • 0022799261 scopus 로고
    • Isolation and characterization of expressible cDNA clones encoding the M1 and M2 subunits of mouse ribonucleotide reductase
    • Thelander L., Berg P. Isolation and characterization of expressible cDNA clones encoding the M1 and M2 subunits of mouse ribonucleotide reductase. Mol. Cell. Biol. 6:1986;3433-3442.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 3433-3442
    • Thelander, L.1    Berg, P.2
  • 10
    • 0021133987 scopus 로고
    • Cell-cycle dependent regulation of mammalian ribonucleotide reductase
    • Eriksson S., Graslund A., Skog S., Thelander L., Tribukait B. Cell-cycle dependent regulation of mammalian ribonucleotide reductase. J. Biol. Chem. 259:1984;11695-11700.
    • (1984) J. Biol. Chem. , vol.259 , pp. 11695-11700
    • Eriksson, S.1    Graslund, A.2    Skog, S.3    Thelander, L.4    Tribukait, B.5
  • 12
    • 0023712808 scopus 로고
    • Ribonucleotide reductase M1 subunit in cellular proliferation, quiescence and differentiation
    • Mann G. J., Musgrove E. A., Fox R. M., Thelander L. Ribonucleotide reductase M1 subunit in cellular proliferation, quiescence and differentiation. Cancer Res. 48:1988;5151-5156.
    • (1988) Cancer Res. , vol.48 , pp. 5151-5156
    • Mann, G.J.1    Musgrove, E.A.2    Fox, R.M.3    Thelander, L.4
  • 13
    • 0025366033 scopus 로고
    • S-phase-specific expression of mammalian ribonucleotide reductase R1 and R2 subunit mRNAs
    • Bjorklund S., Skog S., Tribukait B., Thelander L. S-phase-specific expression of mammalian ribonucleotide reductase R1 and R2 subunit mRNAs. Biochemistry. 29:1990;5452-5458.
    • (1990) Biochemistry , vol.29 , pp. 5452-5458
    • Bjorklund, S.1    Skog, S.2    Tribukait, B.3    Thelander, L.4
  • 14
    • 0023801509 scopus 로고
    • Molecular mechanisms responsible for the drug-induced post-transcriptional modulation of ribonucleotide reductase levels in a hydroxyurea-resistant mouse L cell line
    • McClarty G. M., Chan A. K., Choy B. K., Thelander L., Wright J. A. Molecular mechanisms responsible for the drug-induced post-transcriptional modulation of ribonucleotide reductase levels in a hydroxyurea-resistant mouse L cell line. Biochemistry. 27:1988;7524-7531.
    • (1988) Biochemistry , vol.27 , pp. 7524-7531
    • McClarty, G.M.1    Chan, A.K.2    Choy, B.K.3    Thelander, L.4    Wright, J.A.5
  • 15
    • 0026461365 scopus 로고
    • Sequence analysis of the large and small subunits of human ribonucleotide reductase: DNA Sequence
    • Pavloff N., Rivard D., Masson S., Shen S.-H., Mes-Masson A.-M. Sequence analysis of the large and small subunits of human ribonucleotide reductase: DNA Sequence. J. DNA Sequencing Mapping. 2:1992;227-234.
    • (1992) J. DNA Sequencing Mapping , vol.2 , pp. 227-234
    • Pavloff, N.1    Rivard, D.2    Masson, S.3    Shen, S.-H.4    Mes-Masson, A.-M.5
  • 16
    • 0029841978 scopus 로고    scopus 로고
    • Interferon augments the cytotoxicity of hydroxyurea without enhancing its activity against the M2 subunit of ribonucleotide reductase: Effects in wild-type and resistant human colon cancer cells
    • Wadler S., Horowitz R., Rao J., Mao X., Schlesinger K., Schwartz E. L. Interferon augments the cytotoxicity of hydroxyurea without enhancing its activity against the M2 subunit of ribonucleotide reductase: effects in wild-type and resistant human colon cancer cells. Cancer. Chemother. Pharmacol. 38:1996;522-528.
    • (1996) Cancer. Chemother. Pharmacol. , vol.38 , pp. 522-528
    • Wadler, S.1    Horowitz, R.2    Rao, J.3    Mao, X.4    Schlesinger, K.5    Schwartz, E.L.6
  • 18
    • 0023913190 scopus 로고
    • Molecular mechanisms of drug resistance involving ribonucleotide reductase: Hydroxyurea resistance in a series of clonally related mouse cell lines selected in the presence of increasing drug concentrations
    • Choy B. K., McClarty G. A., Chan A. K., Thelander L., Wright J. A. Molecular mechanisms of drug resistance involving ribonucleotide reductase: hydroxyurea resistance in a series of clonally related mouse cell lines selected in the presence of increasing drug concentrations. Cancer Res. 48:1988;2029-2035.
    • (1988) Cancer Res. , vol.48 , pp. 2029-2035
    • Choy, B.K.1    McClarty, G.A.2    Chan, A.K.3    Thelander, L.4    Wright, J.A.5
  • 19
    • 0028928261 scopus 로고
    • Overexpression of ribonucleotide reductase in transfected human KB cells increases their resistance to hydroxyurea: M2, but not M1 is sufficient to increase resistance to hydroxyurea in transfected cells
    • Zhou B.-S., Hsu N.-Y., Pan B.-C., Doroshow J. H., Yen Y. Overexpression of ribonucleotide reductase in transfected human KB cells increases their resistance to hydroxyurea: M2, but not M1 is sufficient to increase resistance to hydroxyurea in transfected cells. Cancer Res. 55:1995;1328-1333.
    • (1995) Cancer Res. , vol.55 , pp. 1328-1333
    • Zhou, B.-S.1    Hsu, N.-Y.2    Pan, B.-C.3    Doroshow, J.H.4    Yen, Y.5
  • 20
    • 0032499432 scopus 로고    scopus 로고
    • Depletion of deoxyribonucleotide triphospates fails to inhibit expression of the G1/S transition state enzyme, ribonucleotide reductase
    • Wadler S., Horowitz R., Zhang H. Y., Schwartz E. L. Depletion of deoxyribonucleotide triphospates fails to inhibit expression of the G1/S transition state enzyme, ribonucleotide reductase. Biochem. Pharmacol. 55:1998;1353-1360.
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1353-1360
    • Wadler, S.1    Horowitz, R.2    Zhang, H.Y.3    Schwartz, E.L.4
  • 21
    • 0030828684 scopus 로고    scopus 로고
    • Ribonucleotide reductase R2 gene expression and changes in drug sensitivity and genome stability
    • Huang A., Fan H., Taylor W. R., Wright J. A. Ribonucleotide reductase R2 gene expression and changes in drug sensitivity and genome stability. Cancer Res. 57:1997;4876-4881.
    • (1997) Cancer Res. , vol.57 , pp. 4876-4881
    • Huang, A.1    Fan, H.2    Taylor, W.R.3    Wright, J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.