Effect of granulocyte-colony stimulating factor on empiric therapy with flomoxef sodium and tobramycin in febrile neutropenic patients with hematological malignancies

International Journal of Hematology

Volumn 69, Issue 2, 1999, Pages 81-88

  Yoshida, Minoru ^a,b   Karasawa, Masamitsu ^c   Naruse, Takuji ^c   Fukuda, Masataka ^d   Hirashima, Kunitake ^d   Oh, Hakumei ^e   Ninomiya, Haruhiko ^f   Abe, Tsukasa ^f   Saito, Kenji ^g   Shishido, Hideo ^g   Moriyama, Yoshiaki ^h   Shibata, Akira ^h   Motoyoshi, Kazuo ⁱ   Nagata, Naokazu ⁱ   Miura, Yasusada ^b  

^a TEIKYO UNIVERSITY   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

^c GUNMA UNIVERSITY   (Japan)

^d SAITAMA MEDICAL UNIVERSITY   (Japan)

^e CHIBA UNIVERSITY   (Japan)

^f UNIVERSITY OF TSUKUBA   (Japan)

^g DOKKYO MEDICAL UNIVERSITY   (Japan)

^h NIIGATA UNIVERSITY   (Japan)

ⁱ NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

Acute myelogenous leukemia; Empiric therapy; Febrile neutropenia; Granulocyte colony stimulating factor

Indexed keywords

ANTIINFECTIVE AGENT; CEPHALOSPORIN DERIVATIVE; FLOMOXEF; GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT PROTEIN; TOBRAMYCIN;

ADOLESCENT; AGED; ARTICLE; BACTEREMIA; BACTERIAL INFECTION; BLOOD DISEASE; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG COMBINATION; DRUG EFFECT; FEMALE; FEVER; HUMAN; IMMUNE DEFICIENCY; LEUKOCYTE COUNT; MALE; MIDDLE AGED; MULTICENTER STUDY; NEUTROPENIA; PNEUMONIA; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADOLESCENT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BACTEREMIA; BACTERIAL INFECTIONS; CEPHALOSPORINS; DRUG THERAPY, COMBINATION; FEMALE; FEVER; FILGRASTIM; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOLOGIC NEOPLASMS; HUMANS; IMMUNOCOMPROMISED HOST; LEUKOCYTE COUNT; MALE; MIDDLE AGED; NEUTROPENIA; PNEUMONIA; RECOMBINANT PROTEINS; TOBRAMYCIN; TREATMENT OUTCOME;

EID: 0033073469     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Klastersky J. Therapy of infections in cancer patients. In: Klastersky J, Schimpff SC, Senn H-J, editors. Handbook of Supportive Care in Cancer. New York: Marcel Dekker, 1995;1-44.
2. Pizzo PA, Meyers J, Freifeld AG, Walsh T. Infections in cancer patients. In: Devita VT Jr, Hellman S, Rosenberg SA, editors. Cancer Principles and Practice of Oncology, 4th edition. Philadelphia, PA: Lippincott, 1993;2292-337.
3. Hughes WT, Armstrong D, Bodey GP, et al. From the Infectious Disease Society of America. Guidelines for the use of antimicrobial agents in neutropenic patients with unexplained fever. J Infect Dis 1990;161:381-96.
4. Bauernfeind A, Schweighart S, Eberlein E, Jungwirth R. In vitro activity and stability against novel beta-lactamases of investigational beta-lactams (Cefepime, Cefpirome, Flomoxef, SCE 2787 and Piperacillin plus Tazobactam) in comparison with established compounds (Cefotaxime, Latamoxef and Piperacillin). Infection 1991;19(suppl 5):S264-75.
5. Yoshida M. Infections in patients with hematological diseases: recent advances in serological diagnosis and empiric therapy. Int J Hematol 1997;66:279-89.
6. Bodey GP, Buckley M, Sathe YS, et al. Quantitative relationships between circulating leukocytes and infection in patients with acute leukemia. Ann Intern Med 1966;64:328-40.
7. Bodey GP, Fainstein V, Elting LS, et al. Beta-lactam regimens for the febrile neutropenic patient. Cancer 1990;65:9-16.
8. Lieschke GJ, Burgess AW. Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor. New Engl J Med 1992;327:28-35.
9. Sheridan WP, Morstyn G, Wolf M, et al. Granulocyte colony-stimulating factor and neutrophil recovery after high-dose chemotherapy and autologous bone marrow transplantation. Lancet 2:1989;891-5.
10. Crawford J, Ozer H, Stoller R. Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small cell lung cancer. New Engl J Med 1991;325:164-70.
11. Gerhartz HH, Engelhard M, Meusers P, et al. Randomized, double-blind, placebo-controlled, phase III study of recombinant human granulocyte-macrophage colony-stimulating factor as adjunct to induction treatment of high-grade malignant non-Hodgkin's lymphomas. Blood 1993;82:2329-39.
12. Maher DW, Lieschke GJ, Green M, et al. Filgrastim in patients with chemotherapy-induced febrile neutropenia: a double-blind, placebo-controlled trial. Ann Intern Med 1994;121:492-501.
13. Mitchell PLR, Morland B, Stevens MCG, et al. Granulocyte colony-stimulating factor in established febrile neutropenia: a randomized study of pediatric patients. J Clin Oncol 1997;15:1163-70.
14. Anaissie EJ, Vartivarian S, Bodey GP, et al. Randomized comparison between antibiotics alone and antibiotics plus granulocyte-macrophage colony-stimulating factor (Escherichia coli-derived) in cancer patients with fever and neutropenia. Am J Med 1996;100:17-23.
15. Vellenga E, Uyl-de Groot CA, deWit R, et al. Randomized placebo-controlled trial of granulocyte-macrophage colony stimulating factor in patients with chemotherapy-related febrile neutropenia. J Clin Oncol 1996;14:619-27.
16. Biesma B, de Vries EGE, Willemse PHB, et al. Efficacy and tolerability of recombinant human granulocyte-macrophage colony-stimulating factor in patients with chemotherapy-related leukopenia and fever. Eur J Cancer 1992;26:932-6.
17. Mayordomo JI, Rivera F, Diaz-Puente M, et al. Improving treatment of chemotherapy-induced neutropenic fever by administration of colony-stimulating factors. J Natl Cancer Inst 1995;87:803-7.
18. Riikonen P, Saarinen UM, Makipernaa A, et al. Recombinant human granulocyte-macrophage colony-stimulating factor in the treatment of febrile neutropenia: a double-blind placebo-controlled study in children. Pediatr Infect Dis J 1994;13:197-202.
19. Hoelzer D. Hematopoietic growth factors-not whether, but when and where. New Engl J Med 1997;336:1822-4.
20. The EORTC International Antimicrobial Therapy Project Group. Three antibiotic regimens in the treatment of infection in febrile granulocytopenic patients with cancer. J Infect Dis 1978;137:14-29.
21. Roilides E, Walsh TJ, Pizzo P, et al. Granulocyte colony-stimulating factor enhances the phagocytic and bactericidal activity of normal and defective human neutrophils. J Infect Dis 1991;163:579-83.
22. Hussein AM, Elkordy M, Peters WP. The use of growth factors with antibiotics in the setting of neutropenic fever. Am J Med 1996;100:15-6.
23. Bron D, Jacob F. Colony-stimulating factors: current applications and perspectives. In: Klastersky J, editor. Infectious Complications of Cancer. Boston: Kluwer Academic Publishers, 1995;245-54.
24. Hughes WT. Treatment of established bacterial and fungal infections in patients with hematologic malignancy. In: Wiernik PH, Canellos GP, Dutcher JP, Kyle RA, editors. Neoplastic Diseases of the Blood, 3rd edition. New York: Churchill Livingstone, 1996;1027-40.