Efficacy and effects of short- and medium-term contraception in the common marmoset (Callithrix jacchus) using melengestrol acetate implants

Journal of Medical Primatology

Volumn 28, Issue 1, 1999, Pages 36-47

  Mohle U ^a   Heistermann, M ^a   Einspanier, A ^a   Hodges, J K ^a  

^a GERMAN PRIMATE CENTER   (Germany)

Author keywords

Body weight; Decidualization; Endometrium; Ovarian activity; Progestin only contraception; Ultrasonography; Uterine morphology

Indexed keywords

CONTRACEPTIVE AGENT; DRUG DERIVATIVE; MELENGESTROL ACETATE; PREGNANEDIOL; PREGNANEDIOL 3 ALPHA GLUCURONIDE; PREGNANEDIOL-3 ALPHA-GLUCURONIDE;

ANIMAL; ANIMAL DISEASE; ARTICLE; CONTRACEPTION; DECIDUA; DRUG EFFECT; DRUG IMPLANT; ECHOGRAPHY; FEMALE; FERTILITY; HISTOLOGY; MARMOSET; METHODOLOGY; OVARY; PHYSIOLOGY; PREGNANCY; TIME; URINE; UTERUS;

ANIMALS; CALLITHRIX; CONTRACEPTION; CONTRACEPTIVE AGENTS, FEMALE; DECIDUA; DRUG IMPLANTS; FEMALE; FERTILITY; MELENGESTROL ACETATE; OVARY; PREGNANCY; PREGNANEDIOL; TIME FACTORS; UTERUS;

EID: 0033072156     PISSN: 00472565     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0684.1999.tb00087.x     Document Type: Article

References (37)

1. ALVAREZ F, BRACHE V, FAUNDES A, TEJADA AS, THEVENIN F: Ultrasonic and endocrine evaluation of ovarian function among Norplant® implant users with regular menses. Contraception 54:275-279, 1996.
2. ASA CS, PORTON I, BAKER AM, PLOTKA ED: Contraception as a management tool for controlling surplus animals. In: Wild Animals In Captivity. Principles and Techniques. DG Kleiman, ME Allen, KV Thompson, S Lumpkin (eds). Chicago: University of Chicago Press 451-467, 1996.
3. BELL RL, PETERLE TJ: Hormone implants control reproduction in white-tailed deer. Wildl Soc Bull 3:152-156, 1975.
4. BETTINGER T, COUGAR D, LEE DR, LASLEY B, WALLIS J: Ovarian hormone concentration and genital swelling patterns in female chimpanzees with Norplant implants. Zoo Biol 16:209-223, 1997.
5. CROXATTO HB, DIAZ S, PAVEZ M, MIRANDA P, BRANDEIS A: Plasma progesterone levels during long-term treatment with levonorgestrel silastic implant. Acta Endocrinol 101:307-311, 1982.
6. DARNEY PD: Hormonal implants: Contraception for a new century. Am J Obstet Gynecol 170:1536-1543, 1994.
7. DEMATTEO K: AZA Contraception advisory group contraception report. I. Primates. First edition. St. Louis Zoological Park, 1997.
8. DIAZ S, ZEPEDA A, MATURANA X, REYES MV, MIRANDA P, CASADO ME, PERALTA O, CROXATTO HB: Fertility regulation in nursing women. IX. Contraceptive performance, duration of lactation, infant growth, and bleeding patterns during use of progesterone vaginal rings, progestin-only pills, Norplant implants, and copper T380-A intrauterine devices. Contraception 56:223-232, 1997.
9. DUNCAN GW, LYSTER SC, HENDRIX JW, CLARK JJ, WEBSTER HD: Biologic effects of melengestrol acetate. Fertil Steril 15:419-432, 1964.
10. EASTMAN SAK, MAKAWITI DW, COLLINS WP, HODGES JK: Pattern of excretion of urinary steroid metabolises during the ovarian cycle and pregnancy in the marmoset monkey. J Endocrinol 102:19-26, 1984.
11. EINSPANIER A, ZARREH-HOSHYARI-KHAH MR, BALVERS M, KERR L, FUHRMANN K, IVELL R: Local relaxin biosynthesis in the ovary and uterus through the oestrous cycle and early pregnancy in the female marmoset monkey (Callithrix jacchus). Human Reprod 12(6):1325-1337, 1997.
12. GATESMAN TJ: Veterinary care of callitrichids. In: Marmosets and Tamarins in Biological and Biomedical Research. C Pryce, L Scott, C Schnell (eds). Salisbury, UK: DSSD Imagery, 78-101, 1997.
13. GERLOFSMA MH, ZWART P, KLAVER PSJ: Review of contraceptive methods in zoo mammals. Verhandlungsbericht des 36. Internationalen Symposiums über Erkrankungen der Zoo-und Wildtiere 36:25-36, 1994.
14. HARRENSTIEN LA, MUNSON L, SEAL US: The American Zoo and Aquarium Association Mammary Cancer Study Group: Mammary cancer in captive wild felids and risk factors for its development: A retrospective study of the clinical behavior of 31 cases. J Zoo Wildl Med 27:468-476, 1996.
15. HAYES KT, FEISTNER ATC, HALLIWELL EC: The effect of contraceptive implants on the behavior of female rodrigues fruit bats, Pteropus rodricensis. Zoo Biol 15:21-36, 1996.
16. HEISTERMANN M, HODGES JK: Endocrine monitoring of the ovarian cycle and pregnancy in the saddle-back tamarin (Saguinus fuscicollis) by measurement of steroid conjugates in urine. Am J Primatol 35:117-127, 1995.
17. HEISTERMANN M, TARI S, HODGES JK: Measurement of fecal steroids for monitoring ovarian function in New World primates, Callitrichidae. J Reprod Fertil 99:243-251, 1993.
18. JEFFCOATE SL: Use of rapid hormone assays in the prediction of ovulation. In: Ovulation: Methods for its Prediction and Detection. John Wiley and Sons, Ltd: Chichester 67-82, 1983.
19. KAZENSKY CA, MUNSON L, SEAL US: The effects of melengestrol acetate on the ovaries of captive wild felids. J Zoo Wildl Med 29:1-5, 1998.
20. KIRKPATRICK JF, TURNER JW JR: Reversible contraception in non-domestic animals. J Zoo Wildl Med 22:392-408, 1991.
21. LEE-PARRITZ DE, ROBERTS E: Efficacy of hormonal contraception in cotton-top tamarins (Saguinus oedipus). AZA Regional Conf Proc 387-390, 1994.
22. LINNEHAN RM, EDWARDS JL: Endometrial adenocarcinoma in a bengal tiger (Panthera tigris bengalensis) implanted with melengestrol acetate. J Zoo Wildlife Med 22:130-134, 1991.
23. MOLLAND JR, CASTRACANE VD, MOREHAEAD DB, LASLEY B, BALDWIN DM, BERGQUIST CA: Immediate postpartum insertion of the Norplant contraceptive device. Fertil Steril 66:4348, 1996.
24. MUNSON L: Adverse effects of contraceptives in carnivores, primates and ungulates. Proceedings of the annual meeting. Am Assoc Zoo Vet 284-289, 1993.
25. MURNANE RD, ZDZIARSKI JM, WALSH DF, KINSEL MJ, MEEHAN TP, KOVARIK P, BRIGGS M, RAVERTY SA, PHILLIPS LG: Melengestrol acetate-induced exuberant decidualization in Goeldi's marmoset (Callimico goeldii) and squirrel monkeys (Saimiri sciureus). J Zoo Wildl Med 27:315-324, 1996.
26. OERKE A-K, EINSPANIER A, HODGES JK: Detection of pregnancy and monitoring patterns of uterine and fetal growth in the marmoset monkey (Callithrix jacchus) by real-time ultrasonography. Am J Primatol 36:1-13, 1995.
27. OERKE A-K, EINSPANIER A, HODGES JK: Noninvasive monitoring of follicle development, ovulation, and corpus luteum formation in the marmoset monkey (Callithrix jacchus) by ultrasonography. Am J Primatol 39:99-113, 1996.
28. PLOTKA ED, SEAL US: Fertility control in white-tailed deer. J Wildl Dis 25:643-646, 1989.
29. PORTUGAL MM, ASA CS: Effects of chronic melengestrol acetate contraceptive treatment on perineal tumescence, body weight, and sociosexual behavior of hamadryas baboons (Papio hamadryas). Zoo Biol 14:251-259, 1995.
30. PRIEDKALNS J: Effect of melengestrol acetate on ovarian follicles, interstitial gland and corpora lutea in the rat: A qualitative morphological study. Z f Zellforschung 93:56-73, 1969.
31. SACHS L: Angewandte Statistik. Springer-Verlag: Berlin, 1975.
32. SAINSBURY T: The humane control of captive marmoset and tamarin populations. Anim welfare 6:231-242, 1997.
33. STABENFELDT GH: Physiologic, pathologic ant therapeutic roles of progestins in domestic animals. J Am Vet Med Assoc 164:311-316, 1974.
34. Progestogen-only contraceptives during lactation: I. Infant growth. World Health Organization Task Force for epidemiological research on reproductive health; special programme of research, development and research training in human reproduction. Contraception 50:35-53, 1994.
35. VALERIO MG: Comparative aspects of contraceptive steroids: Effects observed in the monkey. Toxicol Pathol 17:401-409, 1989.
36. VAN ELSACKER L, HEISTERMANN M, HODGES JK, DE LAET A, VERHEYEN RF: Preliminary results on the evaluation of contraceptive implants in golden-headed lion tamarins, Leontopithecus chrysomelas. Neotrop Primat 2 (suppl.):30-32, 1994.
37. YARBROUGH LW, TOLLETT JL, MONTREY RD, BEATTIE RJ: Serum biochemical, haematological and body measurement data for common marmosets. Lab Anim Sci 34:276-280, 1984.