Neutrophil dysfunction: The cellular mechanism of impaired immunity during total parenteral nutrition in infancy

Journal of Pediatric Surgery

Volumn 34, Issue 2, 1999, Pages 242-245

  Okada, Yasuhiro ^a   Klein, Nigel J ^a   Pierro, Agostino ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Coagulase negative staphylococci; Neutrophil intracellular killing; Total parenteral nutrition; Whole blood killing

Indexed keywords

BACTERIAL INFECTION; BACTERICIDAL ACTIVITY; CLINICAL ARTICLE; COAGULASE NEGATIVE STAPHYLOCOCCUS; CONFERENCE PAPER; DISEASE ASSOCIATION; FLOW CYTOMETRY; HUMAN; IMMUNE DEFICIENCY; INFANT; LEUKOCYTE FUNCTION; NEUTROPHIL; PEDIATRIC SURGERY; PRIORITY JOURNAL; TOTAL PARENTERAL NUTRITION; ADULT; ARTICLE; BACTEREMIA; IMMUNOLOGY; NEWBORN; NONPARAMETRIC TEST; SERUM BACTERICIDAL ACTIVITY; STAPHYLOCOCCUS;

ADULT; BACTEREMIA; BLOOD BACTERICIDAL ACTIVITY; FLOW CYTOMETRY; HUMANS; INFANT; INFANT, NEWBORN; NEUTROPHILS; PARENTERAL NUTRITION, TOTAL; STAPHYLOCOCCUS; STATISTICS, NONPARAMETRIC;

EID: 0033069523     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-3468(99)90182-3     Document Type: Conference Paper

References (25)

1. Baker CJ, Melish ME, Hall RT, et al: Intravenous immune globulin for the prevention of nosocomial infection in low-birth-weight neonates. N Engl J Med 327:213-219, 1992
2. Bhattacharyya N, Kosloske AM, Macarthur C: Nosocomial infection in pediatric surgical patients: A study of 608 infants and children. J Pediatr Surg 28:338-344, 1993
3. Alverdy JC, Aoys E, Moss GS: Total parenteral nutrition promotes bacterial translocation from the gut. Surgery 104:185-190, 1988
4. Pierro A, vanSaene HKF, Donnell SC, et al: Microbial translocation in neonates on long-term parenteral nutrition. Arch Surg 131:176-179, 1996
5. Pierro A, vanSaene HKF, Jones MO, et al: Clinical impact of abnormal gut flora in infants receiving parenteral nutrition. Ann Surg 227:547-552, 1998
6. Monson JRT, Ramsden CW, MacFie J, et al: Immunorestorative effects of lipid emulsion during total parenteral nutrition. Br J Surg 73:843-846, 1986
7. Sedman PC, Somers SS, Ramsden CW, et al: Effects of different lipid emulsions on lymphocyte function during total parenteral nutrition. Br J Surg 78:1396-1399, 1991
8. Palmblad J, Broström O, Lahnborg G, et al: Neutrophil functions during total parenteral nutrition and Intralipid infusion. Am J Clin Nutr 35:1430-1436, 1982
9. Fisher GW, Hunter KW, Wilson SR, et al: Diminished bacterial defences with intralipid. Lancet 2:819-820, 1980
10. Okada Y, Klein N, Pierro A, et al: The immune response to invading bacteria is impaired in neonates receiving parenteral nutrition. Proc Nutr Soc 56:p218A, 1997
11. Martin E, Bhakdi S: Flow cytometric assay for quantifying opsonophagocytosis and killing of Staphylococcus aureus by peripheral blood leukocytes. J Clin Microbiol 30:2246-2255, 1992
12. Klein NJ, Kalabalikis P, Curtis N, et al: Ex-vivo assessment of candidate anti-inflammatory agents in the treatment of Gram-negative sepsis. Immun Infect Dis 4:33-35, 1994
13. Ison CA, Heyderman R, Klein NJ, et al: Whole blood model of meningococcal bacteraemia - A method for exploring host-bacterial interactions. Microbiol Pathogenesis 18:97-107, 1995
14. Klein NJ, Ison CA, Peakman M, et al: The influence of capsulation and lipooligosaccarides structure on neutrophil adhesion molecule expression and endothelial injury by Neisseria meningitidis. J Infect Dis 173:172-179, 1996
15. Ogata ES, Schulman S, Raffensperger J, et al: Caval catheterization in the intensive care nursery: A useful means for providing patenteral nutrition to the extremely low birth-weight infant. J Pediatr Surg 19:258-262, 1984
16. Bos AP, Tibboel D, Hazebroeck FWJ, et al: Total parenteral nutrition associated cholestasis: A predisposing factor for sepsis in surgical neonates? Eur J Pediatr 149:351-353, 1990
17. Freeman J, Goldmann DA, Smith NE, et al: Association of intravenous lipid emulsion and coagulase-negative staphylococcal bacteremia in neonatal intensive care unit. N Engl J Med 323:301-308, 1990
18. Patrick CC: Coagulase-negative staphylococci: Pathogens with increasing clinical significance. J Pediatr 116:497-507, 1990
19. Fleer A, Gerards LJ, Aerts P, et al: Opsonic defence to Staphylococcus epidermidis in the premature neonate. J Infect Dis 152:930-937, 1985
20. Fleer A, Verhoef J, Hernandez AP: Coagulase-negative staphylococci as nasocomial pathogen in neonates. Am J Med 80:161-165, 1986 (Suppl 6B)
21. Shiro H, Muller E, Takeda S, et al: Potentiation of Staphylococcus epidermidis catheter-related bacteremia by lipid infusions. J Infect Dis 171:220-224, 1995
22. Nataro JP, Corcoran L, Zirin S, et al: Prospective analysis of coagulase-negative staphylococcal infection in hospitalised infants. J Pediatr 125:798-804, 1994
23. Vowells SJ, Sekhsaria S, Malech HL, et al: Flow cytometric analysis of the granulocyte respiratory burst: A comparison study of fluorescent probes: J Immunol Methods 178:89-97, 1995
24. Jaswon MS, Jones HM, Linch DC: The effect of recombinant human granulocyte-macrophage colony stimulating factor on the neutrophil respiratory burst in the term and preterm infant when studied in whole blood. Pediatr Res 36:623-627, 1994
25. Okada Y, Papp E, Klein N, et al: Total parenteral nutrition directly impairs cytokine production after bacterial challenge. J Pediatr Surg (in press)