Polyamines found in the inflamed periodontium inhibit priminq and apoptosis in human polymorphonuclear leukocytes

Journal of Periodontology

Volumn 70, Issue 2, 1999, Pages 179-184

  Ratasirayakorn, Waraporn ^a   Leone, Peter ^a   Leblebicioglu, Binnaz ^b   Walters, John D ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b Ohio State University ^*

Author keywords

Apoptosis; Neutrophils; Periodontal diseases physiopathology; Polyamines; Respiratory burst; Superoxides; Tumor necrosis factor

Indexed keywords

ACRIDINE ORANGE; CYTOCHROME C; DIAGNOSTIC AGENT; ETHIDIUM; FLUORESCENT DYE; POLYAMINE; PUTRESCINE; SPERMIDINE; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA;

ANALYSIS OF VARIANCE; APOPTOSIS; ARTICLE; CELL NUCLEUS; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; FLUORESCENCE MICROSCOPY; HUMAN; METABOLISM; NEUTROPHIL; OXIDATION REDUCTION REACTION; PATHOLOGY; PERIODONTITIS; RESPIRATORY BURST; TIME;

ACRIDINE ORANGE; ANALYSIS OF VARIANCE; APOPTOSIS; BIOGENIC POLYAMINES; CELL NUCLEUS; CYTOCHROME C GROUP; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHIDIUM; FLUORESCENT DYES; HUMANS; MICROSCOPY, FLUORESCENCE; NEUTROPHILS; OXIDATION-REDUCTION; PERIODONTAL POCKET; PERIODONTITIS; PUTRESCINE; RESPIRATORY BURST; SPERMIDINE; SUPEROXIDES; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033069280     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.1999.70.2.179     Document Type: Article

References (35)

1. Steinbeck MJ, Roth JA. Neutrophil activation by recombinant cytokines. Rev Infect Dis 1989;11:549-568.
2. Hallet MB, Lloyds D. Neutrophil priming: The cellular signals that say "amber" but not "green." Immunol Today 1995;16:264-268.
3. Savill J. Apoptosis in resolution of inflammation. J Leukoc Biol 1997;61:375-380.
4. Whyte MKB, Meagher LC, MacDermot J, Haslett C. Impairment of function in aging neutrophils is associated with apoptosis. J Immunol 1993;150:5124-5134.
5. Narayanan PK, Ragheb K, Lawler G, Robinson JP. Defects in intracellular oxidative metabolism of neutrophils undergoing apoptosis. J Leukoc Biol 1997;61:481-488.
6. Haslett C. Resolution of acute inflammation and the role of apoptosis in the tissue fate of granulocytes. Clin Sci 1992;83:639-648.
7. Savill JS, Wyllie AH, Henson JE, Walport MJ, Henson PM, Haslett C. Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages. J Clin Invest 1989;83:865-867.
8. Payne CM, Glasser L, Tischler ME, et al. Programmed cell death of the normal human neutrophil: An in vitro model of senescence. Microsc Res Tech 1994;28:327-344.
9. Colatta F, Re F, Polentarutti N, Sozzani S, Mantovani A. Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products. Blood 1992;80:2012-2020.
10. Lee A, Whyte MKB, Haslett C. Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators. J Leukoc Biol 1993;54:283-288.
11. Lamster IB, Mandella RD, Zove SM, Harper DS. The polyamines putrescine, spermidine, and spermine in human gingival crevicular fluid. Arch Oral Biol 1987;32:329-333.
12. Walters JD. Polyamine analysis of human gingival crevicular fluid. J Periodont Res 1987;22:522-523.
13. Schuber F. Influence of polyamines on membrane function. Biochem J 1989;260: 1-10.
14. Abraham AK, Pihl A. Role of polyamines in macromolecular synthesis. Trends Biochem Sci 1981;6:106-107.
15. Walters JD, Wojcik MS. Polyamine transport in human promyelocytic leukemia cells and polymorphonuclear leukocytes. Leukemia Res 1994;18:703-708.
16. Walters JD, Cario AC, Leblebicioglu B, Fernandez MC, Marucha PT. An inhibitor of polyamine biosynthesis impairs human polymorphonuclear leukocyte priming by tumor nerosis factor-α. J Leukoc Biol 1995;57:282-286.
17. Walters JD, Cario AC, Danne MM, Marucha PT. An inhibitor of ornithine decarboxylase antagonizes superoxide generation by primed human polymorphonuclear leukocyte. J Inflamm 1998;48:40-46.
18. Fuerstein BG, Williams LD, Basu HS, Marton LJ. Implications and concepts of polyamine-nucleic acid interactions. J Cell Biochem 1991;46:37-47.
19. Khan AU, Mei Y-H, Wilson T. A proposed function for spermine and spermidine: Protection of replicating DNA against damage by singlet oxygen. Proc Natl Acad Sci (USA) 1992;89:11426-11427.
20. Brune B, Hartzell P, Nicotera P, Orrenius S. Spermine prevents endonuclease activation and apoptosis in thymocytes. Exp Cell Res 1991;195:323-329.
21. Boyum A. Isolation of mononuclear cells and granulocytes from human peripheral blood. Scand J Clin Lab Invest 1968;21:77-89.
22. Babior B, Kipnes R, Curnette J. The production by leukocytes of superoxide: A potential bactericidal agent. J Clin Invest 1973;52:741-744.
23. Loser C, Wunderich U, Folsch UR. Reversed-phase liquid chromatographic separation and simultaneous fluorometric detection of polyamines and their monoacetyl derivatives in human and animal urine, serum and tissue samples: A rapid and sensitive method for routine application. J Chromatogr 1988;430:249-262.
24. Duke RC, Cohen JJ. Morphological and biochemical assays of apoptosis. Curr Protocols Immunol 1992;17:1-16.
25. Gu Y, Jow GM, Moulton GM, et al. Apoptosis in decidual tissue regression and reorganization. Endocrinol 1994;135:1272-1279.
26. McColl SR, Beauseigle D, Gilbert C, Naccache PH. Priming of the human neutrophil respiratory burst by granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-α involves regulation at a post-cell surface receptor level. J Immunol 1990;145:3047-3053.
27. Stashenko P, Jardinski JJ, Fujiyoshi P, Rynar J, Socransky SS. Tissue levels of bone resorptive cytokines in periodontal disease. J Periodontol 1991;62:504-509.
28. Rossomando EF, Kennedy JE, Hadjimichael J. Tumor necrosis factor alpha in gingival crevicular fluid as a possible indicator of periodontal disease in humans. Arch Oral Biol 1990;35:431-434.
29. Calkins C, Platt K, Potempa J, Travis J. Inactivation of TNF-α by proteinases (gingipains) from the periodontal pathogen, Porphyromonas gingivalis: Implications of immune evasion. J Biol Chem 1998;273:6611-6614.
30. Ishida H, Iwayama Y, Daikuhara Y. Changes in polyamine metabolism during experimental periodontitis in dogs and the role of putrescine in recovery. Arch Oral Biol 1983;28:51-60.
31. Tabor CW, Tabor H. Polyamines. Ann Rev Biochem 1984;53:749-790.
32. Walters JD, Chapman KJ. Polyamines found in gingival fluid enhance the secretory and oxidative function of human polymorphonuclear leukocytes in vitro. J Periodont Res 1995;29:167-171.
33. Hung DT, Marton LJ, Deen DF, Shafer RH. Depletion of intracellular polyamines may alter DNA conformation in 9L rat brain tumor cells. Science 1983;221:368-370.
34. Sharry JJ, Krasse B. Observations on the origin of salivary leukocytes. Acta Odontol Scand 1960;18:348-358.
35. 111 Indium-labelled polymorphonuclear leukocytes into the oral cavity of the rhesus monkey. J Periodont Res 1979;14:475-481.